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anti-ZBTB8A antibody :: Rabbit anti-Human, Mouse ZBTB8 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS150061
Unit / Price
0.1 mg  /  $365 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ZBTB8 (ZBTB8A), Polyclonal Antibody

 Also Known As   

ZBTB8 Antibody

 Product Synonym Names    ZBTB8; BOZF1; ZBTB8; ZNF916A; BOZF1; Zinc finger and BTB domain-containing protein 8A; BOZ-F1; zinc finger and BTB domain containing 8
 Product Gene Name   

anti-ZBTB8A antibody

[Similar Products]
 Antibody/Peptide Pairs    ZBTB8 peptide (MBS152713) is used for blocking the activity of ZBTB8 antibody (MBS150061)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q96BR9
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Specificity    At least two isoforms of ZBTB8 are known to exist; this antibody will recognize both isoforms. This antibody is predicted to not cross-react with other ZBTB protein family members.
 Purity/Purification    ZBTB8 Antibody is affinity chromatography purified via peptide column.
 Form/Format    Liquid
 Concentration    1 mg/mL (lot specific)
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 Conjugate    Unconjugated
 Immunogen    ZBTB8 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human ZBTB8.
 Buffer    ZBTB8 Antibody is supplied in PBS containing 0.02% sodium azide.
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 Preparation and Storage    ZBTB8 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
 Other Notes    Small volumes of anti-ZBTB8A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-ZBTB8A antibody

   ZBTB8 Antibody: The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB8, also known as BOZ-F1, is present in multiple tissues, and is highly expressed in the cytoplasm of the placenta. While little is known about ZBTB8, other ZBTB proteins, such as ZBTB4 bind methylated DNA and repress transcription. Another ZBTB proteins, ZBTB7A, has been implicated as a proto-oncogene whose overexpression contributes to malignancy in breast cancer, suggesting that ZBTB8 may act as a transcriptional repressor or be involved in tumorigenesis.
 Applications Tested/Suitable for anti-ZBTB8A antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

 Application Notes for anti-ZBTB8A antibody    ZBTB8 antibody can be used for detection of ZBTB8 by Western blot at 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 5 mug/mL.
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 Western Blot (WB) of anti-ZBTB8A antibody    Western blot analysis of ZBTB8 in mouse spleen tissue lysate with ZBTB8 antibody at 1 μg/mL.
anti-ZBTB8A antibody Western Blot (WB) (WB) image
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 Immunofluorescence (IF) of anti-ZBTB8A antibody    Immunofluorescence ofZBTB8 in human spleen tissue with ZBTB8 antibody at 20 μg/mL.
anti-ZBTB8A antibody Immunofluorescence (IF) image
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 Immunohistochemistry (IHC) of anti-ZBTB8A antibody    Immunohistochemistry of ZBTB8 in human spleen tissue with ZBTB9 antibody at 2.5 μg/mL.
anti-ZBTB8A antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for ZBTB8A. It may not necessarily be applicable to this product.
 NCBI GI #    94721342
 NCBI GeneID    653121
 NCBI Accession #    CAI20024 [Other Products]
 NCBI GenBank Nucleotide #    NM_001040441.1 [Other Products]
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 UniProt Primary Accession #    Q96BR9 [Other Products]
 UniProt Secondary Accession #    Q8IUL5; Q8IWR9; Q8N2Y5; Q96BX0 [Other Products]
 UniProt Related Accession #    Q96BR9 [Other Products]
 Molecular Weight    38,344 Da
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 NCBI Official Full Name    zinc finger and BTB domain-containing protein 8A
 NCBI Official Synonym Full Names    zinc finger and BTB domain containing 8A
 NCBI Official Symbol    ZBTB8A [Similar Products]
 NCBI Official Synonym Symbols   
BOZF1; ZBTB8; ZNF916A
[Similar Products]
 NCBI Protein Information    zinc finger and BTB domain-containing protein 8A; zinc finger and BTB domain containing 8; BTB/POZ and zinc-finger domain-containing factor; BTB/POZ and zinc-finger domains factor on chromosome 1
 UniProt Protein Name    Zinc finger and BTB domain-containing protein 8A
 UniProt Synonym Protein Names   
BTB/POZ and zinc-finger domain-containing factor; BTB/POZ and zinc-finger domains factor on chromosome 1; BOZ-F1
 Protein Family    Zinc finger and BTB domain-containing protein
 UniProt Gene Name    ZBTB8A [Similar Products]
 UniProt Synonym Gene Names    BOZF1; BOZ-F1 [Similar Products]
 UniProt Entry Name    ZBT8A_HUMAN
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 UniProt Comments for ZBTB8A    ZBTB8: May be involved in transcriptional regulation. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 1p35.1

Cellular Component: nucleus

Molecular Function: DNA binding; metal ion binding

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent
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 Research Articles on ZBTB8A    1. Data indicate BOZF1 represses transcription of CDKN1A by inhibition of p53 acetylation and Sp1 binding.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Organs/Tissues associated with anti-ZBTB8A antibody
 Organ/Tissue Name  Pubmed Publications
 Prostate Antibodies  >1 publications with ZBTB8A and Prostate
 Brain Antibodies  >1 publications with ZBTB8A and Brain
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