NP_056151.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
22,845 Da
NCBI Official Full Name
palmitoyltransferase ZDHHC17
NCBI Official Synonym Full Names
zinc finger, DHHC-type containing 17
NCBI Protein Information
palmitoyltransferase ZDHHC17
UniProt Protein Name
Palmitoyltransferase ZDHHC17
UniProt Synonym Protein Names
Huntingtin yeast partner H
UniProt Synonym Gene Names
UniProt Entry Name
ZDH17_HUMAN
UniProt Comments for ZDHHC17
HIP14: a palmitoyltransferase specific for a subset of neuronal proteins, including SNAP25, PSD-95, GAD2, SYT1 and Huntingtin. May be involved in the sorting or targeting of critical proteins involved in the initiating events of endocytosis at the plasma membrane. May be involved in the NF-kappa-B signaling pathway. Can cause cellular transformation, and is up-regulated in a number of types of human tumors. Expressed in all brain regions. Expression is highest in the cortex, cerebellum, occipital lobe and caudate, and lowest in the spinal cord. Expression is also seen in testis, pancreas, heart and kidney. Three alternatively spliced isoforms have been described.
Protein type: EC 2.3.1.225; Tumor suppressor; Transferase; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 12q21.2
Cellular Component: cytoplasm; Golgi apparatus; Golgi membrane; integral to membrane; intracellular membrane-bound organelle
Molecular Function: identical protein binding; magnesium ion transmembrane transporter activity; palmitoyltransferase activity; protein binding; protein-cysteine S-palmitoleyltransferase activity; signal transducer activity; zinc ion binding
Biological Process: lipoprotein transport; positive regulation of I-kappaB kinase/NF-kappaB cascade; protein palmitoylation; signal transduction
Product References and Citations for anti-ZDHHC17 antibody
Singaraja R.R.,et al.Hum. Mol. Genet. 11:2815-2828(2002). Nagase T.,et al.DNA Res. 6:63-70(1999). Matsuda A.,et al.Oncogene 22:3307-3318(2003). Ota T.,et al.Nat. Genet. 36:40-45(2004). Faber P.W.,et al.Hum. Mol. Genet. 7:1463-1474(1998).
Research Articles on ZDHHC17
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Products associated with anti-ZDHHC17 antibody
Diseases associated with anti-ZDHHC17 antibody
Organs/Tissues associated with anti-ZDHHC17 antibody
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