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anti-NS5 antibody :: Rabbit Zika Virus NS5 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS5400284 anti-NS5 antibody
Unit / Price
0.1 mg Affinity-Purified  /  $390 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Zika Virus NS5, Polyclonal Antibody

 Also Known As   

Rabbit Polyclonal Anti-ZIKANS5 antibody

 Product Synonym Names    NS5 zika virus; RNA-dependent RNA polymerase NS5; nonstructural protein 5 antibody
 Product Gene Name   

anti-NS5 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
 Matching Pairs    Antibody: Zika Virus NS5 (MBS5400284)
Positive Control: Zika Virus NS5 (MBS543408)
 Antibody/Peptide Pairs    Zika Virus NS5 peptide (MBS544673) is used for blocking the activity of Zika Virus NS5 antibody (MBS5400284)
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Zika virus
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 Form/Format    Affinity Purified
 Concentration    0.65 mg/ml IgG in antibody stabilization buffer (lot specific)
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 Immunogen    Synthetic pepitde taken within amino acid region 3230-3280 on Zika virus NS5 protein.
 Immunoglobulin    IgG
 Molecular Function    ATP binding; RNA-directed RNA polymerase activity
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 Preparation and Storage    -20 degree C for long term storage
 Other Notes    Small volumes of anti-NS5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-NS5 antibody

   Zika virus (ZIKV) is an arthropod-borne virus (arbovirus) in the genus Flavivirus and the family Flaviviridae. The Zika virus is a sense single-stranded RNA virus (sssRNA) (also described as SSRNA positive sense virus, no DNA stage). The rapid spread of Zika virus through the Americas, together with the association of infection with microcephaly and Guillain-Barré syndrome, has resulted in the World Health Organization declaring a public health emergency. Its >10,000 bases code for three structural proteins (capsid (C), precursor membrane (prM), envelop (E)) and seven nonstructural proteins (NS). The NS2A, NS2B, NS4A, and NS4B proteins are smaller, hydrophobic proteins while NS1, NS3, and NS5 are large and highly conserved. Zika virus has the potential to spread to new areas where the Aedes mosquito vector is present and therefore presents a risk to the United States (1). Using single-cell RNA-seq and immunohistochemistry, it has been found that the candidate viral entry receptor AXL is highly expressed by human radial glial cells, astrocytes, endothelial cells, and microglia in developing human cortex and by progenitor cells in developing retina. It is also reported that AXL expression in radial glia is conserved in developing mouse and ferret cortex and in human stem cell-derived cerebral organoids, highlighting multiple experimental systems that could be applied to study mechanisms of ZIKV infectivity and effects on brain development (2).
 Product Categories/Family for anti-NS5 antibody    Primary Antibodies; Cell Biology; Host Virus Interaction; Zika Virus NS5 Antibody
 Applications Tested/Suitable for anti-NS5 antibody   

ELISA (EIA)

 Application Notes for anti-NS5 antibody    ELISA: 1:10,000
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NCBI/Uniprot data below describe general gene information for NS5. It may not necessarily be applicable to this product.
 NCBI GI #    973447405
 NCBI Accession #    ALX35659.1 [Other Products]
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 NCBI Official Full Name    polyprotein
 UniProt Protein Name    Genome polyprotein
 UniProt Entry Name    A0A0U4DG08_ZIKV
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products related to Rabbit Polyclonal Anti-ZIKANS5 antibody
 Catalog #  Product Name  Catalog #  Product Name
 MBS5400284  Rabbit Polyclonal Anti-ZIKANS5 antibody  MBS5400286  Zika Virus NS5 Antibody FITC-Conjugated
 MBS5400285  Zika Virus NS5 Antibody BIOTIN-Conjugated  MBS544673  Zika Virus NS5 Peptide
 MBS543408  Zika Virus NS5 Positive Control
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