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anti-SLC39A2 antibody :: Rabbit anti-Human Zinc Transporter ZIP2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS630429 anti-SLC39A2 antibody
Unit / Price
0.1 mL  /  $745 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Zinc Transporter ZIP2 (SLC39A2), Polyclonal Antibody

 Also Known As   

Anti-Zinc Transporter ZIP2 (Solute Carrier Family 39 Member 2, Zrt- and Irt-like Protein 2, ZIP-2, hZIP2, SLC39A2, 6A1, Eti-1, ZIP2)

 Product Synonym Names    Solute Carrier Family 39 Member 2; Zrt- and Irt-like Protein 2; ZIP-2; hZIP2; SLC39A2; 6A1; Eti-1; ZIP2
 Product Gene Name   

anti-SLC39A2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 14; NC_000014.8 (21467414..21470034). Location: 14q11.2
 3D Structure    ModBase 3D Structure for Q9NP94
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    Recognizes human ZIP2. Species sequence homology: mouse (84%).
 Purity/Purification    Affinity Purified
 Form/Format    Supplied as a liquid in PBS, 0.1% BSA.
 Concentration    ~1mg/ml (lot specific)
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 Immunogen    Synthetic peptide corresponding to 19aa of human ZIP2 (Accession #AAI13770), N-terminal, Extracellular domain (KLH).
 Source Information    Human
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 Preparation and Storage    May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Shipping Temperature: Blue Ice
 Other Notes    Small volumes of anti-SLC39A2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-SLC39A2 antibody

   Zinc is an essential nutrient for all organisms because of the many important roles this metal plays. Movement of zinc into and out of cells and subcellular organelles is mediated by zinc transporter proteins. In many organisms, zinc uptake is mediated by members of the ZIP family of metal ion transporters. In mammals, the Zip1, Zip2, Zip3, Zip4, Zip5, LIV- 1 (Zip6), KE4 (Zip7), and BIGM103 (Zip8) proteins have been implicated in zinc uptake in a variety of cell and tissue types.

ZIP2 ((SLC39A2; Eti-1; 6A1)) encodes a protein of 309aa, includes an amino terminal signal peptide of 26aa, and has the predicted topology of Zip proteins. The human or mouse Zip2 overexpression in transfected K562 and human embryonic kidney (HEK293) cells, respectively, increased 65Zn uptake in these cells. hZIP2-induced Zn uptake was shown to be highly inhibited by Mn2+ and Co2+, metals that did not substantially affect hZIP1-, mZIP1-, or mZIP2-induced Zn uptake. Zn uptake mediated by hZIP2 appears to be stimulated by HCO 3, non-ATP dependent, but sensitive to N-ethylmaleimide, a sulfhydryl-reactive agent.
 Product Categories/Family for anti-SLC39A2 antibody    Abs to Ion Transport
 Applications Tested/Suitable for anti-SLC39A2 antibody   

ELISA; Western Blot; Immunohistochemistry

 Application Notes for anti-SLC39A2 antibody    Suitable for use in Western Blot, ELISA, and Immunohistochemistry.
Recommended Dilutions: Western Blot: 1-10ug/ml (Chemiluminescence)
ELISA: 1:100,000
Immunohistochemistry: 2-10ug/ml
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NCBI/Uniprot data below describe general gene information for SLC39A2. It may not necessarily be applicable to this product.
 NCBI GI #    156415986
 NCBI GeneID    29986
 NCBI Accession #    NP_055394.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_014579.3 [Other Products]
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 UniProt Primary Accession #    Q9NP94 [Other Products]
 UniProt Secondary Accession #    Q4QQJ1; Q4V9S4; Q96JT6; Q9UD20; B2RC76 [Other Products]
 UniProt Related Accession #    Q9NP94 [Other Products]
 Molecular Weight    32,742 Da [Similar Products]
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 NCBI Official Full Name    zinc transporter ZIP2
 NCBI Official Synonym Full Names    solute carrier family 39 (zinc transporter), member 2
 NCBI Official Symbol    SLC39A2 [Similar Products]
 NCBI Official Synonym Symbols   
6A1; ZIP2; Eti-1; ZIP-2; MGC119190
[Similar Products]
 NCBI Protein Information    zinc transporter ZIP2; OTTHUMP00000164402; Zrt- and Irt-like protein 2; solute carrier family 39 member 2
 UniProt Protein Name    Zinc transporter ZIP2
 UniProt Synonym Protein Names   
6A1; Eti-1; Solute carrier family 39 member 2; Zrt- and Irt-like protein 2
 Protein Family    Zinc transporter
 UniProt Gene Name    SLC39A2 [Similar Products]
 UniProt Synonym Gene Names    ZIP2 [Similar Products]
 UniProt Entry Name    S39A2_HUMAN
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-SLC39A2 antibodyPathways associated with anti-SLC39A2 antibody
 Reference Product  PubMed Publications
 SLC39A1 antibody  >6 publications with SLC39A2 and SLC39A1
 Products by Pathway  Pathway Diagram
 Metal Ion SLC Transporters Pathway antibodies  Metal Ion SLC Transporters Pathway Diagram
 SLC-mediated Transmembrane Transport Pathway antibodies  SLC-mediated Transmembrane Transport Pathway Diagram
 Senescence And Autophagy Pathway antibodies  Senescence And Autophagy Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway antibodies  Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway Diagram
 Zinc Influx Into Cells By The SLC39 Gene Family Pathway antibodies  Zinc Influx Into Cells By The SLC39 Gene Family Pathway Diagram
 Zinc Transporters Pathway antibodies  Zinc Transporters Pathway Diagram
Diseases associated with anti-SLC39A2 antibodyOrgans/Tissues associated with anti-SLC39A2 antibody
 Disease Name  Pubmed Publications
 Skin Diseases Antibodies  >1 publications with SLC39A2 and Skin Diseases
 Asthma Antibodies  >1 publications with SLC39A2 and Asthma
 Prostatic Neoplasms Antibodies  >1 publications with SLC39A2 and Prostatic Neoplasms
 Lung Diseases Antibodies  >1 publications with SLC39A2 and Lung Diseases
 Mammary Neoplasms, Experimental Antibodies  >1 publications with SLC39A2 and Mammary Neoplasms, Experimental
 Cardiovascular Diseases Antibodies  >1 publications with SLC39A2 and Cardiovascular Diseases
 Acrodermatitis Antibodies  >1 publications with SLC39A2 and Acrodermatitis
 Organ/Tissue Name  Pubmed Publications
 Prostate Antibodies  >2 publications with SLC39A2 and Prostate
 Embryonic Tissue Antibodies  >1 publications with SLC39A2 and Embryonic Tissue
 Placenta Antibodies  >1 publications with SLC39A2 and Placenta
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