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anti-Ttpa antibody :: Rabbit a-Tocopherol Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS612102 anti-Ttpa antibody
Unit / Price
0.1 mg  /  $845 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

a-Tocopherol (Ttpa), Polyclonal Antibody

★Popular Item★
 Also Known As   

a-Tocopherol (Vitamin E), Conjugated

 Product Synonym Names    Anti -a-Tocopherol (Vitamin E), Conjugated
 Product Gene Name   

anti-Ttpa antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 5; NC_005104.2 (34638551..34659077). Location: 5q21
 3D Structure    ModBase 3D Structure for P41034
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
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 Specificity    Recognizes protein-linked alpha-Tocopherol (vitamin E). ELISA test results:
 Purity/Purification    Purified
Antiserum previously preabsobed on protein carriers, and purified by ammonium sulfate precipitation and gel filtration.
 Form/Format    Supplied as a liquid, pH 7.2. No preservative added.
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 Immunogen    Synthetic alpha-Tocopherol acid succinate, conjugated with BSA.
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 Preparation and Storage    May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
 Other Notes    Small volumes of anti-Ttpa antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-Ttpa antibody

   alpha-Tocopherol is a form of vitamin E that is preferentially absorbed and accumulated in humans. The measurement of "vitamin E" activity in international units (IU) was based on fertility enhancement by the prevention of spontaneous abortions in pregnant rats relative to alpha-Tocopherol.
 Product Categories/Family for anti-Ttpa antibody    Antibodies; Abs to Vitamins
 Applications Tested/Suitable for anti-Ttpa antibody   

ELISA (EL/EIA), Immunohistochemistry (IHC)

 Application Notes for anti-Ttpa antibody    Suitable for use in ELISA and Immunohistochemistry.
Dilution: Immunohistochemistry: 1:500-1:2000
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NCBI/Uniprot data below describe general gene information for Ttpa. It may not necessarily be applicable to this product.
 NCBI GI #    6981682
 NCBI GeneID    25571
 NCBI Accession #    NP_037180.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_013048.2 [Other Products]
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 UniProt Primary Accession #    P41034 [Other Products]
 UniProt Related Accession #    P41034 [Other Products]
 Molecular Weight    31,846 Da [Similar Products]
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 NCBI Official Full Name    alpha-tocopherol transfer protein
 NCBI Official Synonym Full Names    tocopherol (alpha) transfer protein
 NCBI Official Symbol    Ttpa [Similar Products]
 NCBI Official Synonym Symbols   
TTP
[Similar Products]
 NCBI Protein Information    alpha-tocopherol transfer protein; alpha-TTP; Tocopherol transfer protein alpha
 UniProt Protein Name    Alpha-tocopherol transfer protein
 Protein Family    Alpha-tocopherol transfer protein
 UniProt Gene Name    Ttpa [Similar Products]
 UniProt Synonym Gene Names    Tpp1 [Similar Products]
 UniProt Entry Name    TTPA_RAT
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 NCBI Summary for Ttpa    binds the vitamin tocopherol and enhances its transfer between separate membranes [RGD, Feb 2006]
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 UniProt Comments for Ttpa    TTPA: Binds alpha-tocopherol and enhances its transfer between separate membranes. Defects in TTPA are the cause of ataxia with isolated vitamin E deficiency (AVED). AVED is an autosomal recessive disease characterized by spinocerebellar degeneration. It causes ataxia and peripheral neuropathy that resembles Friedreich ataxia. AVED patients have markedly reduced plasma levels of vitamin E.

Protein type: Transporter

Cellular Component: late endosome; cytosol

Molecular Function: phosphatidylinositol-4,5-bisphosphate binding; transporter activity; vitamin binding; phosphatidylinositol-3,4-bisphosphate binding; vitamin E binding

Biological Process: vitamin E metabolic process; embryonic placenta development; response to toxin; intracellular pH reduction; intermembrane transport; vitamin transport; developmental process; response to nutrient; response to pH; placenta development
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 Research Articles on Ttpa    1. findings show that intracellular processing of tocopherol involves a functional interaction between TTP and an ABC-type transporter.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-Ttpa antibodyOrgans/Tissues associated with anti-Ttpa antibody
 Disease Name  Pubmed Publications
 Heart Diseases Antibodies  >3878 publications with Ttpa and Heart Diseases
 Inflammation Antibodies  >1110 publications with Ttpa and Inflammation
 Venous Thrombosis Antibodies  >991 publications with Ttpa and Venous Thrombosis
 Hypertension Antibodies  >711 publications with Ttpa and Hypertension
 Arteriosclerosis Antibodies  >489 publications with Ttpa and Arteriosclerosis
 Fibrosis Antibodies  >470 publications with Ttpa and Fibrosis
 Kidney Diseases Antibodies  >425 publications with Ttpa and Kidney Diseases
 Liver Diseases Antibodies  >404 publications with Ttpa and Liver Diseases
 Neoplasm Metastasis Antibodies  >358 publications with Ttpa and Neoplasm Metastasis
 Adenocarcinoma Antibodies  >315 publications with Ttpa and Adenocarcinoma
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2399 publications with Ttpa and Brain
 Liver Antibodies  >798 publications with Ttpa and Liver
 Lung Antibodies  >703 publications with Ttpa and Lung
 Inner Ear Antibodies  >6 publications with Ttpa and Inner Ear
 Uncharacterized Tissue Antibodies  >5 publications with Ttpa and Uncharacterized Tissue
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