AAH01467.1
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Acireductone dioxygenase 1
NCBI Official Synonym Full Names
acireductone dioxygenase 1
NCBI Official Synonym Symbols
ARD; APL1; SIPL; mtnD; Fe-ARD; MTCBP1; Ni-ARD; HMFT1638 [Similar Products]
NCBI Protein Information
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; ARD; ADI1; fe-ARD; MTCBP-1; submergence induced protein 2; submergence-induced protein-like factor; MT1-MMP cytoplasmic tail-binding protein-1; acireductone dioxygenase (Fe(2+)-requiring); acireductone dioxygenase (Ni(2+)-requiring); membrane-type 1 matrix metalloproteinase cytoplasmic tail binding protein-1
UniProt Protein Name
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase
UniProt Synonym Protein Names
Acireductone dioxygenase (Fe(2+)-requiring); Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1
UniProt Entry Name
MTND_HUMAN
NCBI Summary for ADI1
This gene encodes an enzyme that belongs to the aci-reductone dioxygenase family of metal-binding enzymes, which are involved in methionine salvage. This enzyme may regulate mRNA processing in the nucleus, and may carry out different functions depending on its localization. Related pseudogenes have been defined on chromosomes 8 and 20. [provided by RefSeq, May 2010]
UniProt Comments for ADI1
ADI1: Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Necessary for hepatitis C virus replication in an otherwise non-permissive cell line. Belongs to the acireductone dioxygenase (ARD) family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Oxidoreductase; Amino Acid Metabolism - cysteine and methionine; EC 1.13.11.54
Chromosomal Location of Human Ortholog: 2p25.3
Cellular Component: nucleoplasm; Golgi apparatus; cytoplasm; plasma membrane; nucleus; cytosol
Molecular Function: acireductone dioxygenase [iron(II)-requiring] activity; protein binding; iron ion binding; oxidoreductase activity
Biological Process: methionine salvage; sulfur amino acid metabolic process; polyamine metabolic process
Research Articles on ADI1
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with anti-ADI1 antibody
Diseases associated with anti-ADI1 antibody
Organs/Tissues associated with anti-ADI1 antibody
|