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anti-ARPC1B antibody :: Rabbit actin related protein 2/3 complex, subunit 1B Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS710568 anti-ARPC1B antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

actin related protein 2/3 complex, subunit 1B (ARPC1B), Polyclonal Antibody

 Also Known As   

Rabbit anti-human actin related protein 2/3 complex, subunit 1B, 41kDa polyclonal Antibody

 Product Synonym Names    actin related protein 2/3 complex; subunit 1B; 41kDa; ARPC1B; ARC41; p40-ARC; p41-ARC
 Product Gene Name   

anti-ARPC1B antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    604223
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human ARPC1B
 Storage Buffer    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-65168 / sc-65169 / sc-65171 / sc-68395
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-ARPC1B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-ARPC1B antibody   

ELISA (EIA), Immunohistochemistry (IHC)

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NCBI/Uniprot data below describe general gene information for ARPC1B. It may not necessarily be applicable to this product.
 NCBI GI #    5031601
 NCBI GeneID    10095
 NCBI Accession #    NP_005711.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_005720.3 [Other Products]
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 UniProt Secondary Accession #    Q9BU00 [Other Products]
 UniProt Related Accession #    O15143 [Other Products]
 Molecular Weight    40,950 Da [Similar Products]
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 NCBI Official Full Name    actin-related protein 2/3 complex subunit 1B
 NCBI Official Synonym Full Names    actin related protein 2/3 complex, subunit 1B, 41kDa
 NCBI Official Symbol    ARPC1B [Similar Products]
 NCBI Official Synonym Symbols   
ARC41; p40-ARC; p41-ARC
[Similar Products]
 NCBI Protein Information    actin-related protein 2/3 complex subunit 1B; arp2/3 complex 41 kDa subunit; ARP2/3 protein complex subunit p41
 UniProt Protein Name    Actin-related protein 2/3 complex subunit 1B
 UniProt Synonym Protein Names   
Arp2/3 complex 41 kDa subunit; p41-ARC
 Protein Family    Actin-related protein 2/3 complex
 UniProt Gene Name    ARPC1B [Similar Products]
 UniProt Synonym Gene Names    ARC41 [Similar Products]
 UniProt Entry Name    ARC1B_HUMAN
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 NCBI Summary for ARPC1B    This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase. [provided by RefSeq, Mar 2011]
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 UniProt Comments for ARPC1B    ARPC1B: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC. Belongs to the WD repeat ARPC1 family.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 7q22.1

Cellular Component: Arp2/3 protein complex; focal adhesion; cytoplasm; actin cytoskeleton

Molecular Function: actin filament binding; structural constituent of cytoskeleton

Biological Process: cell motility
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 Research Articles on ARPC1B    1. p41-Arc activates a senescence program in p53- and Rb-independent ways.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ARPC1B antibodyPathways associated with anti-ARPC1B antibody
 Reference Product  PubMed Publications
 ACTR2 antibody  >1 publications with ARPC1B and ACTR2
 ACTR3 antibody  >1 publications with ARPC1B and ACTR3
 ARPC3 antibody  >1 publications with ARPC1B and ARPC3
 ARPC2 antibody  >1 publications with ARPC1B and ARPC2
 Products by Pathway  Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 Bacterial Invasion Of Epithelial Cells Pathway antibodies  Bacterial Invasion Of Epithelial Cells Pathway Diagram
 Bacterial Invasion Of Epithelial Cells Pathway antibodies  Bacterial Invasion Of Epithelial Cells Pathway Diagram
 CDC42 Signaling Events Pathway antibodies  CDC42 Signaling Events Pathway Diagram
 ErbB1 Downstream Signaling Pathway antibodies  ErbB1 Downstream Signaling Pathway Diagram
 Fc Gamma R-mediated Phagocytosis Pathway antibodies  Fc Gamma R-mediated Phagocytosis Pathway Diagram
 Fc Gamma R-mediated Phagocytosis Pathway antibodies  Fc Gamma R-mediated Phagocytosis Pathway Diagram
 Pathogenic Escherichia Coli Infection Pathway antibodies  Pathogenic Escherichia Coli Infection Pathway Diagram
 Pathogenic Escherichia Coli Infection Pathway antibodies  Pathogenic Escherichia Coli Infection Pathway Diagram
 Pathogenic Escherichia Coli Infection Pathway antibodies  Pathogenic Escherichia Coli Infection Pathway Diagram
Diseases associated with anti-ARPC1B antibodyOrgans/Tissues associated with anti-ARPC1B antibody
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >3 publications with ARPC1B and Carcinoma
 Ovarian Diseases Antibodies  >1 publications with ARPC1B and Ovarian Diseases
 Lung Neoplasms Antibodies  >1 publications with ARPC1B and Lung Neoplasms
 Breast Neoplasms Antibodies  >1 publications with ARPC1B and Breast Neoplasms
 Inflammation Antibodies  >1 publications with ARPC1B and Inflammation
 Adenocarcinoma Antibodies  >1 publications with ARPC1B and Adenocarcinoma
 Necrosis Antibodies  >1 publications with ARPC1B and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Stomach Antibodies  >4 publications with ARPC1B and Stomach
 Bone Antibodies  >2 publications with ARPC1B and Bone
 Blood Antibodies  >2 publications with ARPC1B and Blood
 Nerve Antibodies  >1 publications with ARPC1B and Nerve
 Esophagus Antibodies  >1 publications with ARPC1B and Esophagus
 Vascular Antibodies  >1 publications with ARPC1B and Vascular
 Bone Marrow Antibodies  >1 publications with ARPC1B and Bone Marrow
 Pancreas Antibodies  >1 publications with ARPC1B and Pancreas
 Lung Antibodies  >1 publications with ARPC1B and Lung
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