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anti-ATF6B antibody :: Rabbit activating transcription factor 6 beta Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS716761 anti-ATF6B antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

activating transcription factor 6 beta (ATF6B), Polyclonal Antibody

 Also Known As   

Rabbit anti-human activating transcription factor 6 beta polyclonal Antibody

 Product Synonym Names    activating transcription factor 6 beta; ATF6B; CREB-RP; CREBL1; FLJ10066; G13
 Product Gene Name   

anti-ATF6B antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    600984
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human ATF6B
 Storage Buffer    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-30597
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-ATF6B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-ATF6B antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

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NCBI/Uniprot data below describe general gene information for ATF6B. It may not necessarily be applicable to this product.
 NCBI GI #    50604104
 NCBI GeneID    1388
 NCBI Accession #    AAH77075.1 [Other Products]
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 UniProt Secondary Accession #    Q13269; Q14343; Q14345; Q5SSW7; Q99635; Q99637; Q9H3V9; Q9H3W1; Q9NPL0; B0UYX6 [Other Products]
 UniProt Related Accession #    Q99941 [Other Products]
 Molecular Weight    76,412 Da [Similar Products]
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 NCBI Official Full Name    Activating transcription factor 6 beta
 NCBI Official Synonym Full Names    activating transcription factor 6 beta
 NCBI Official Symbol    ATF6B [Similar Products]
 NCBI Official Synonym Symbols   
G13; CREBL1; CREB-RP
[Similar Products]
 NCBI Protein Information    cyclic AMP-dependent transcription factor ATF-6 beta; protein G13; Creb-related protein; cAMP responsive element binding protein-like 1; cAMP-dependent transcription factor ATF-6 beta; cAMP-responsive element-binding protein-like 1; cAMP response element-binding protein-related protein
 UniProt Protein Name    Cyclic AMP-dependent transcription factor ATF-6 beta
 UniProt Synonym Protein Names   
Activating transcription factor 6 beta; ATF6-beta; Protein G13; cAMP response element-binding protein-related protein; Creb-rp; cAMP-responsive element-binding protein-like 1Cleaved into the following chain:Processed cyclic AMP-dependent transcription factor ATF-6 beta
 Protein Family    Cyclic AMP-dependent transcription factor
 UniProt Gene Name    ATF6B [Similar Products]
 UniProt Synonym Gene Names    CREBL1; G13; cAMP-dependent transcription factor ATF-6 beta; ATF6-beta; Creb-rp [Similar Products]
 UniProt Entry Name    ATF6B_HUMAN
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 NCBI Summary for ATF6B    The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
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 UniProt Comments for ATF6B    ATF6B: Transcriptional factor that acts in the unfolded protein response (UPR) pathway by activating UPR target genes induced during ER stress. Binds DNA on the 5'-CCAC[GA]-3' half of the ER stress response element (ERSE) (5'-CCAATN(9)CCAC[GA]-3') when NF-Y is bound to ERSE. Belongs to the bZIP family. ATF subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Transcription factor

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Component: Golgi apparatus; endoplasmic reticulum membrane; integral to endoplasmic reticulum membrane; intracellular; nucleus

Molecular Function: protein binding; sequence-specific DNA binding; transcription factor activity

Biological Process: transcription, DNA-dependent; unfolded protein response; signal transduction
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 Research Articles on ATF6B    1. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-ATF6B antibodyDiseases associated with anti-ATF6B antibody
 Products by Pathway  Pathway Diagram
 Adrenergic Signaling In Cardiomyocytes Pathway antibodies  Adrenergic Signaling In Cardiomyocytes Pathway Diagram
 Adrenergic Signaling In Cardiomyocytes Pathway antibodies  Adrenergic Signaling In Cardiomyocytes Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Cocaine Addiction Pathway antibodies  Cocaine Addiction Pathway Diagram
 Cocaine Addiction Pathway antibodies  Cocaine Addiction Pathway Diagram
 Dopaminergic Synapse Pathway antibodies  Dopaminergic Synapse Pathway Diagram
 Dopaminergic Synapse Pathway antibodies  Dopaminergic Synapse Pathway Diagram
 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >1 publications with ATF6B and Brain Diseases
 Nervous System Diseases Antibodies  >1 publications with ATF6B and Nervous System Diseases
 Cognition Disorders Antibodies  >1 publications with ATF6B and Cognition Disorders
Organs/Tissues associated with anti-ATF6B antibody
 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >2 publications with ATF6B and Heart
 Prostate Antibodies  >1 publications with ATF6B and Prostate
 Lung Antibodies  >1 publications with ATF6B and Lung
 Brain Antibodies  >1 publications with ATF6B and Brain
 Thyroid Antibodies  >1 publications with ATF6B and Thyroid
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