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anti-ADRBK2 antibody :: Rabbit adrenergic, beta, receptor kinase 2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS713681 anti-ADRBK2 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

adrenergic, beta, receptor kinase 2 (ADRBK2), Polyclonal Antibody

 Also Known As   

Rabbit anti-human adrenergic, beta, receptor kinase 2 polyclonal Antibody

 Product Synonym Names    adrenergic; beta; receptor kinase 2; ADRBK2; BARK2; GRK3
 Product Gene Name   

anti-ADRBK2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    109636
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human ADRBK2
 Storage Buffer    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-28891 / sc-563
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-ADRBK2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-ADRBK2 antibody   

ELISA (EIA), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for ADRBK2. It may not necessarily be applicable to this product.
 NCBI GI #    119580104
 NCBI GeneID    157
 NCBI Accession #    EAW59700.1 [Other Products]
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 UniProt Secondary Accession #    Q9UGW9 [Other Products]
 UniProt Related Accession #    P35626 [Other Products]
 Molecular Weight    79,710 Da [Similar Products]
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 NCBI Official Full Name    adrenergic, beta, receptor kinase 2, isoform CRA_b
 NCBI Official Synonym Full Names    adrenergic, beta, receptor kinase 2
 NCBI Official Symbol    ADRBK2 [Similar Products]
 NCBI Official Synonym Symbols   
GRK3; BARK2
[Similar Products]
 NCBI Protein Information    beta-adrenergic receptor kinase 2; beta-ARK-2; G-protein-coupled receptor kinase 3
 UniProt Protein Name    Beta-adrenergic receptor kinase 2
 UniProt Synonym Protein Names   
G-protein-coupled receptor kinase 3
 Protein Family    Beta-adrenergic receptor kinase
 UniProt Gene Name    ADRBK2 [Similar Products]
 UniProt Synonym Gene Names    BARK2; GRK3; Beta-ARK-2 [Similar Products]
 UniProt Entry Name    ARBK2_HUMAN
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 NCBI Summary for ADRBK2    The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ADRBK2    GRK3: Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

Protein type: Protein kinase, AGC; EC 2.7.11.15; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; AGC group; GRK family; BARK subfamily

Chromosomal Location of Human Ortholog: 22q12.1

Molecular Function: G-protein coupled receptor kinase activity; beta-adrenergic receptor kinase activity; ATP binding; protein kinase activity

Biological Process: receptor internalization; signal transduction; protein amino acid phosphorylation
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 Research Articles on ADRBK2    1. data are consistent with the possibility that oncogenes can induce cellular stiffness via an HDAC6-induced reorganization of the vimentin intermediate filament network
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ADRBK2 antibodyPathways associated with anti-ADRBK2 antibody
 Reference Product  PubMed Publications
 ADRB2 antibody  >19 publications with ADRBK2 and ADRB2
 CXCR4 antibody  >8 publications with ADRBK2 and CXCR4
 TBXA2R antibody  >2 publications with ADRBK2 and TBXA2R
 CCR5 antibody  >1 publications with ADRBK2 and CCR5
 CCR4 antibody  >1 publications with ADRBK2 and CCR4
 Products by Pathway  Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Corticotropin-releasing Hormone Pathway antibodies  Corticotropin-releasing Hormone Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Glutamatergic Synapse Pathway antibodies  Glutamatergic Synapse Pathway Diagram
 Glutamatergic Synapse Pathway antibodies  Glutamatergic Synapse Pathway Diagram
 IL-4 Signaling Pathway antibodies  IL-4 Signaling Pathway Diagram
 Morphine Addiction Pathway antibodies  Morphine Addiction Pathway Diagram
 Morphine Addiction Pathway antibodies  Morphine Addiction Pathway Diagram
Diseases associated with anti-ADRBK2 antibodyOrgans/Tissues associated with anti-ADRBK2 antibody
 Disease Name  Pubmed Publications
 Bipolar Disorder Antibodies  >14 publications with ADRBK2 and Bipolar Disorder
 Heart Diseases Antibodies  >8 publications with ADRBK2 and Heart Diseases
 Hypertension Antibodies  >7 publications with ADRBK2 and Hypertension
 Brain Diseases Antibodies  >6 publications with ADRBK2 and Brain Diseases
 Hypertrophy Antibodies  >4 publications with ADRBK2 and Hypertrophy
 Inflammation Antibodies  >4 publications with ADRBK2 and Inflammation
 Asthma Antibodies  >3 publications with ADRBK2 and Asthma
 Respiratory Tract Diseases Antibodies  >2 publications with ADRBK2 and Respiratory Tract Diseases
 Movement Disorders Antibodies  >2 publications with ADRBK2 and Movement Disorders
 Necrosis Antibodies  >2 publications with ADRBK2 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >39 publications with ADRBK2 and Brain
 Muscle Antibodies  >25 publications with ADRBK2 and Muscle
 Blood Antibodies  >22 publications with ADRBK2 and Blood
 Heart Antibodies  >20 publications with ADRBK2 and Heart
 Kidney Antibodies  >10 publications with ADRBK2 and Kidney
 Eye Antibodies  >9 publications with ADRBK2 and Eye
 Vascular Antibodies  >9 publications with ADRBK2 and Vascular
 Nerve Antibodies  >8 publications with ADRBK2 and Nerve
 Embryonic Tissue Antibodies  >4 publications with ADRBK2 and Embryonic Tissue
 Ovary Antibodies  >3 publications with ADRBK2 and Ovary
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