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anti-ASGR2 antibody :: Rabbit anti-Human asialoglycoprotein receptor 2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS711746 anti-ASGR2 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

asialoglycoprotein receptor 2 (ASGR2), Polyclonal Antibody

 Also Known As   

Rabbit anti-human asialoglycoprotein receptor 2 polyclonal Antibody

 Product Synonym Names    asialoglycoprotein receptor 2; ASGR2; ASGP-R; CLEC4H2; Hs.1259; L-H2
 Product Gene Name   

anti-ASGR2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    108361
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human ASGR2
 Storage Buffer    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-13471 / sc-13472 / sc-292647 / sc-130964
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-ASGR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-ASGR2 antibody   

ELISA (EIA), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for ASGR2. It may not necessarily be applicable to this product.
 NCBI GI #    16878088
 NCBI GeneID    433
 NCBI Accession #    AAH17251.1 [Other Products]
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 UniProt Secondary Accession #    O00448; Q03969; A6NLV8; A8MT12; D3DTM9; D3DTN0 [Other Products]
 UniProt Related Accession #    P07307 [Other Products]
 Molecular Weight    32,550 Da [Similar Products]
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 NCBI Official Full Name    Asialoglycoprotein receptor 2
 NCBI Official Synonym Full Names    asialoglycoprotein receptor 2
 NCBI Official Symbol    ASGR2 [Similar Products]
 NCBI Official Synonym Symbols   
HL-2; HBXBP; ASGPR2; ASGP-R2; CLEC4H2
[Similar Products]
 NCBI Protein Information    asialoglycoprotein receptor 2; hepatic lectin H2; HBxAg-binding protein; C-type lectin domain family 4 member H2
 UniProt Protein Name    Asialoglycoprotein receptor 2
 UniProt Synonym Protein Names   
C-type lectin domain family 4 member H2; Hepatic lectin H2; HL-2
 Protein Family    Asialoglycoprotein receptor
 UniProt Gene Name    ASGR2 [Similar Products]
 UniProt Synonym Gene Names    CLEC4H2; ASGP-R 2; ASGPR 2; HL-2 [Similar Products]
 UniProt Entry Name    ASGR2_HUMAN
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 NCBI Summary for ASGR2    This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
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 UniProt Comments for ASGR2    ASGP-R: cell surface receptor that mediates the endocytosis of plasma glycoproteins in which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociates. Then the receptor is recycled back to the cell surface. There are four alternatively spliced transcript variants of this gene.

Protein type: Receptor, misc.; Membrane protein, integral

Chromosomal Location of Human Ortholog: 17p

Cellular Component: integral to membrane

Molecular Function: protein binding; asialoglycoprotein receptor activity; carbohydrate binding

Biological Process: receptor-mediated endocytosis; cell surface receptor linked signal transduction; glycoprotein metabolic process; lipid homeostasis; regulation of protein stability; bone mineralization
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 Research Articles on ASGR2    1. the distribution of ASGR in human testis, was investigated.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ASGR2 antibodyPathways associated with anti-ASGR2 antibody
 Reference Product  PubMed Publications
 ASGR1 antibody  >3 publications with ASGR2 and ASGR1
 Products by Pathway  Pathway Diagram
 Thyroid Hormone Synthesis Pathway antibodies  Thyroid Hormone Synthesis Pathway Diagram
 Thyroid Hormone Synthesis Pathway antibodies  Thyroid Hormone Synthesis Pathway Diagram
Diseases associated with anti-ASGR2 antibodyOrgans/Tissues associated with anti-ASGR2 antibody
 Disease Name  Pubmed Publications
 Hepatitis Antibodies  >1 publications with ASGR2 and Hepatitis
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >3 publications with ASGR2 and Liver
 Blood Antibodies  >2 publications with ASGR2 and Blood
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