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anti-ASNS antibody :: Rabbit asparagine synthetase Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS719220 anti-ASNS antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

asparagine synthetase (ASNS), Polyclonal Antibody

 Also Known As   

Rabbit anti-human asparagine synthetase polyclonal Antibody

 Product Synonym Names    asparagine synthetase; ASNS; TS11
 Product Gene Name   

anti-ASNS antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    gene 615574
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human ASNS
 Storage Buffer    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-46787 / sc-46785 / sc-135183
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-ASNS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-ASNS antibody   

ELISA (EIA), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for ASNS. It may not necessarily be applicable to this product.
 NCBI GI #    533200
 NCBI GeneID    440
 NCBI Accession #    AAA52756.1 [Other Products]
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 UniProt Secondary Accession #    P08184; Q15666; Q549T9; Q96HD0; A4D1I8; B4DXZ1; B7ZAA9; D6W5R3; E9PCI3; E9PCX6 [Other Products]
 UniProt Related Accession #    P08243 [Other Products]
 Molecular Weight    54,818 Da [Similar Products]
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 NCBI Official Full Name    asparagine synthetase
 NCBI Official Synonym Full Names    asparagine synthetase (glutamine-hydrolyzing)
 NCBI Official Symbol    ASNS [Similar Products]
 NCBI Official Synonym Symbols   
TS11; ASNSD
[Similar Products]
 NCBI Protein Information    asparagine synthetase [glutamine-hydrolyzing]; asparagine synthetase [glutamine-hydrolyzing]; TS11 cell cycle control protein; glutamine-dependent asparagine synthetase
 UniProt Protein Name    Asparagine synthetase [glutamine-hydrolyzing]
 UniProt Synonym Protein Names   
Cell cycle control protein TS11; Glutamine-dependent asparagine synthetase
 Protein Family    Asparagine synthetase
 UniProt Gene Name    ASNS [Similar Products]
 UniProt Synonym Gene Names    TS11 [Similar Products]
 UniProt Entry Name    ASNS_HUMAN
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 NCBI Summary for ASNS    The protein encoded by this gene is involved in the synthesis of asparagine. This gene complements a mutation in the temperature-sensitive hamster mutant ts11, which blocks progression through the G1 phase of the cell cycle at nonpermissive temperature. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2010]
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 UniProt Comments for ASNS    ASNS: 3 isoforms of the human protein are produced by alternative splicing

Protein type: Cell cycle regulation; Energy Metabolism - nitrogen; EC 6.3.5.4; Ligase; Amino Acid Metabolism - alanine, aspartate and glutamate

Chromosomal Location of Human Ortholog: 7q21.3

Cellular Component: cytosol

Molecular Function: protein homodimerization activity; asparagine synthase (glutamine-hydrolyzing) activity; cofactor binding; ATP binding

Biological Process: response to light stimulus; unfolded protein response; response to toxin; glutamine metabolic process; liver development; positive regulation of mitotic cell cycle; response to amino acid stimulus; cellular response to hormone stimulus; cellular response to glucose starvation; unfolded protein response, activation of signaling protein activity; asparagine biosynthetic process; cellular protein metabolic process; response to mechanical stimulus; amino acid biosynthetic process; response to methotrexate; response to follicle-stimulating hormone stimulus; negative regulation of apoptosis

Disease: Asparagine Synthetase Deficiency
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 Research Articles on ASNS    1. ASNS deficiency is correlated with poor therapeutic response and worse survivals in patients with rectal cancer receiving neoadjuvant CCRT
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ASNS antibodyPathways associated with anti-ASNS antibody
 Reference Product  PubMed Publications
 ATF4 antibody  >20 publications with ASNS and ATF4
 ASS1 antibody  >2 publications with ASNS and ASS1
 GOT1 antibody  >1 publications with ASNS and GOT1
 Products by Pathway  Pathway Diagram
 ATF4 Activates Genes Pathway antibodies  ATF4 Activates Genes Pathway Diagram
 Alanine, Aspartate And Glutamate Metabolism Pathway antibodies  Alanine, Aspartate And Glutamate Metabolism Pathway Diagram
 Alanine, Aspartate And Glutamate Metabolism Pathway antibodies  Alanine, Aspartate And Glutamate Metabolism Pathway Diagram
 Amino Acid Synthesis And Interconversion (transamination) Pathway antibodies  Amino Acid Synthesis And Interconversion (transamination) Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 PERK Regulates Gene Expression Pathway antibodies  PERK Regulates Gene Expression Pathway Diagram
 Unfolded Protein Response (UPR) Pathway antibodies  Unfolded Protein Response (UPR) Pathway Diagram
Diseases associated with anti-ASNS antibodyOrgans/Tissues associated with anti-ASNS antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >6 publications with ASNS and Nervous System Diseases
 Breast Neoplasms Antibodies  >4 publications with ASNS and Breast Neoplasms
 Brain Diseases Antibodies  >4 publications with ASNS and Brain Diseases
 Liver Neoplasms Antibodies  >3 publications with ASNS and Liver Neoplasms
 Liver Diseases Antibodies  >3 publications with ASNS and Liver Diseases
 Cardiovascular Diseases Antibodies  >3 publications with ASNS and Cardiovascular Diseases
 Carcinoma, Hepatocellular Antibodies  >2 publications with ASNS and Carcinoma, Hepatocellular
 Hypertension Antibodies  >2 publications with ASNS and Hypertension
 Seizures Antibodies  >2 publications with ASNS and Seizures
 Fibrosis Antibodies  >2 publications with ASNS and Fibrosis
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >16 publications with ASNS and Blood
 Liver Antibodies  >6 publications with ASNS and Liver
 Lung Antibodies  >6 publications with ASNS and Lung
 Bone Antibodies  >6 publications with ASNS and Bone
 Brain Antibodies  >5 publications with ASNS and Brain
 Bone Marrow Antibodies  >4 publications with ASNS and Bone Marrow
 Vascular Antibodies  >4 publications with ASNS and Vascular
 Nerve Antibodies  >3 publications with ASNS and Nerve
 Thyroid Antibodies  >3 publications with ASNS and Thyroid
 Kidney Antibodies  >3 publications with ASNS and Kidney
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