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anti-BVES antibody :: Rabbit blood vessel epicardial substance Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS713119 anti-BVES antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

blood vessel epicardial substance (BVES), Polyclonal Antibody

 Also Known As   

Rabbit anti-human blood vessel epicardial substance polyclonal Antibody

 Product Synonym Names    blood vessel epicardial substance; BVES; HBVES; MGC42413; POP1; POPDC1
 Product Gene Name   

anti-BVES antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    604577
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human BVES
 Storage Buffer    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-49889
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-BVES antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-BVES antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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NCBI/Uniprot data below describe general gene information for BVES. It may not necessarily be applicable to this product.
 NCBI GI #    313760596
 NCBI GeneID    11149
 NCBI Accession #    NP_001186492.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001199563.1 [Other Products]
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 UniProt Secondary Accession #    Q5T550; Q5T551; Q8IWC6; Q9HBV0; Q9UNG6; A8K1R4; E1P5D8 [Other Products]
 UniProt Related Accession #    Q8NE79 [Other Products]
 Molecular Weight    41,451 Da [Similar Products]
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 NCBI Official Full Name    blood vessel epicardial substance
 NCBI Official Synonym Full Names    blood vessel epicardial substance
 NCBI Official Symbol    BVES [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    blood vessel epicardial substance; popeye protein 1; popeye domain containing 1; popeye domain-containing protein 1
 UniProt Protein Name    Blood vessel epicardial substance
 UniProt Synonym Protein Names   
Popeye domain-containing protein 1; Popeye protein 1
 Protein Family    Blood vessel epicardial substance
 UniProt Gene Name    BVES [Similar Products]
 UniProt Synonym Gene Names    POP1; POPDC1; hBVES; Popeye protein 1 [Similar Products]
 UniProt Entry Name    POPD1_HUMAN
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 NCBI Summary for BVES    This gene encodes a member of the POP family of proteins containing three putative transmembrane domains. This gene is expressed in cardiac and skeletal muscle and may play an important role in development of these tissues. The mouse ortholog may be involved in the regeneration of adult skeletal muscle and may act as a cell adhesion molecule in coronary vasculogenesis. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2010]
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 UniProt Comments for BVES    BVES: Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells. Plays a role in VAMP3- mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and in the regulation of cell spreading. Belongs to the popeye family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 6q21

Cellular Component: tight junction; integral to membrane; plasma membrane; lateral plasma membrane

Molecular Function: cAMP binding; structural molecule activity

Biological Process: vesicle-mediated transport; regulation of cell shape; positive regulation of locomotion; muscle development; regulation of membrane potential; regulation of heart rate; hemopoietic progenitor cell differentiation; positive regulation of receptor recycling
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 Research Articles on BVES    1. These results suggest that down-regulation of BVES in hepatocellular carcinoma induces epithelial-mesenchymal transition, thus promoting invasion and metastasis in HCC cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-BVES antibodyDiseases associated with anti-BVES antibody
 Reference Product  PubMed Publications
 KCNH5 antibody  >2 publications with BVES and KCNH5
 ZDHHC5 antibody  >1 publications with BVES and ZDHHC5
 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >4 publications with BVES and Adenocarcinoma
 Heart Defects, Congenital Antibodies  >2 publications with BVES and Heart Defects, Congenital
 Congenital Abnormalities Antibodies  >2 publications with BVES and Congenital Abnormalities
 Liver Neoplasms Antibodies  >1 publications with BVES and Liver Neoplasms
 Intestinal Neoplasms Antibodies  >1 publications with BVES and Intestinal Neoplasms
 Fibrosis Antibodies  >1 publications with BVES and Fibrosis
 Liver Diseases Antibodies  >1 publications with BVES and Liver Diseases
Organs/Tissues associated with anti-BVES antibody
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >30 publications with BVES and Muscle
 Heart Antibodies  >22 publications with BVES and Heart
 Blood Antibodies  >20 publications with BVES and Blood
 Embryonic Tissue Antibodies  >15 publications with BVES and Embryonic Tissue
 Lung Antibodies  >5 publications with BVES and Lung
 Skin Antibodies  >3 publications with BVES and Skin
 Brain Antibodies  >2 publications with BVES and Brain
 Liver Antibodies  >1 publications with BVES and Liver
 Uterus Antibodies  >1 publications with BVES and Uterus
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