AAH33674.1
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Bol, boule-like (Drosophila)
NCBI Official Synonym Full Names
boule-like RNA-binding protein
NCBI Official Synonym Symbols
NCBI Protein Information
protein boule-like; bol, boule-like
UniProt Protein Name
Protein boule-like
UniProt Synonym Gene Names
UniProt Entry Name
BOLL_HUMAN
NCBI Summary for BOLL
This gene belongs to the DAZ gene family required for germ cell development. It encodes an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes DAZ (deleted in azoospermia) or DAZL (deleted in azoospermia-like). Loss of this gene function results in the absence of sperm in semen (azoospermia). Histological studies demonstrated that the primary defect is at the meiotic G2/M transition. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for BOLL
BOLL: Probable RNA-binding protein, which may be required during spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation. Belongs to the RRM DAZ family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Translation
Chromosomal Location of Human Ortholog: 2q33
Cellular Component: cytoplasm
Molecular Function: protein binding; translation activator activity; RNA binding; nucleotide binding
Biological Process: positive regulation of translational initiation; meiosis; multicellular organismal development; spermatogenesis; cell differentiation
Research Articles on BOLL
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Products associated with anti-BOLL antibody
Diseases associated with anti-BOLL antibody
Organs/Tissues associated with anti-BOLL antibody
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