View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Add To Compare List anti-c-Jun antibody :: Rabbit anti-Human c-Jun Polyclonal Antibody Catalog # MBS8000542 Unit / Price DISCONTINUEDClick here to view our similar product(s) OR click here to contact our technical support team for suitable replacement. Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name c-Jun, Polyclonal Antibody Full Product Name c-Jun Antibody: ATTO 680 Product Synonym Names Rabbit Anti-Human c-Jun Polyclonal; AP 1 Antibody; Proto-oncogene c-Jun Antibody; cJun Antibody; Enhancer Binding Protein AP1 Antibody; p39 Antibody; JUN Antibody; JUN_HUMAN Antibody; V jun avian sarcoma virus 17 oncogene homolog Antibody; Jun Activation Domain Binding Protein Antibody; JUNC Antibody; Transcription Factor AP 1 Antibody; Oncogene JUN Antibody; V-jun avian sarcoma virus 17 oncogene homolog Antibody; Jun proto oncogene Antibody; Proto oncogene c jun Antibody; Transcription Factor AP1 Antibody; V jun sarcoma virus 17 oncogene homolog Antibody; Proto-oncogene c-jun Antibody; Proto oncogene cJun Antibody; V jun sarcoma virus 17 oncogene homolog (avian) Antibody; AP1 Antibody; Activator protein 1 Antibody; JUN protein Antibody; Jun oncogene Antibody; Transcription factor AP-1 Antibody; vJun Avian Sarcoma Virus 17 Oncogene Homolog Antibody Product Gene Name anti-c-Jun antibody[Similar Products] Matching Pairs Unconjugated Antibody: c-Jun (MBS8000535)ATTO 680 Conjugated Antibody: c-Jun (MBS8000542) Matching Pairs Unconjugated Antibody: N/A (MBS8000542)ATTO 680 Conjugated Antibody: c-Jun (MBS8000542) Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP OMIM 165160 3D Structure ModBase 3D Structure for P05412 Clonality Polyclonal Host Rabbit Species Reactivity Human Specificity Detects 35.7 kDa, band at 25 kDa is possible degradation product. Purity/Purification Peptide Affinity Purified Concentration 1 mg/ml (lot specific) Target c-Jun Immunogen Synthetic peptide of Human c-Jun (200-300 aa), conjugated to Keyhole Limpet Haemocyanin (KLH). Immunogen Species Human Cellular Localization Nucleus Conjugate ATTO 680 Storage Buffer PBS pH 7.4, 50% glycerol, 0.09% Sodium Azide Preparation and Storage Store at -20 degree C. Other Notes Small volumes of anti-c-Jun antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Product Categories/Family for anti-c-Jun antibody Antibodies; Cell Signaling; Epigenetics and Nuclear Signaling; Transcription; Domain Families; Hlh; Cell Signaling; Epigenetics and Nuclear Signaling; Nuclear Signaling Pathways; SMADs; Cell Signaling; Epigenetics and Nuclear Signaling; Transcription; Tra Applications Tested/Suitable for anti-c-Jun antibody Western Blot (WB) Application Notes for anti-c-Jun antibody WB: 1:1000 Western Blot (WB) of anti-c-Jun antibody Western blot analysis of Human Cervical cancer cell line (HeLa) lysate showing detection of ~35.7 kDa c-Jun protein using Rabbit Anti-c-Jun Polyclonal Antibody (SPC-728). Lane 1: Molecular Weight Ladder (MW). Lane 2: Cervical Cancer cell line (HeLa) lysate. Load: 10 ug. Block: 5% Skim Milk in 1X TBST. Primary Antibody: Rabbit Anti-c-Jun Polyclonal Antibody (SPC-728) at 1:1000 for 2 hours at RT. Secondary Antibody: Goat Anti-Rabbit HRP:IgG at 1:3000 for 1 hour at RT. Color Development: ECL solution for 5 min at RT. Predicted/Observed Size: ~35.7 kDa. Other Band(s): ~25 kDa potential degradation product. TOP NCBI/Uniprot data below describe general gene information for c-Jun. It may not necessarily be applicable to this product. NCBI GI # 4758616 NCBI GeneID 3725 NCBI Accession # NP_002219.1 [Other Products] NCBI GenBank Nucleotide # NM_002228.3 [Other Products] UniProt Primary Accession # P05412 [Other Products] UniProt Secondary Accession # Q6FHM7; Q96G93[Other Products] UniProt Related Accession # P05412[Other Products] Molecular Weight 35,676 Da TOP NCBI Official Full Name transcription factor AP-1 NCBI Official Synonym Full Names Jun proto-oncogene, AP-1 transcription factor subunit NCBI Official Symbol JUN [Similar Products] NCBI Official Synonym Symbols AP1; p39; AP-1; c-Jun [Similar Products] NCBI Protein Information transcription factor AP-1 UniProt Protein Name Transcription factor AP-1 UniProt Synonym Protein Names Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39 Protein Family C-Jun-amino-terminal kinase-interacting protein UniProt Gene Name JUN [Similar Products] UniProt Synonym Gene Names AP1 [Similar Products] TOP NCBI Summary for c-Jun This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. [provided by RefSeq, Jul 2008] TOP UniProt Comments for c-Jun Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306). Research Articles on c-Jun 1. Increased c-jun expression is associated with nasopharyngeal carcinoma. 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TOP Products associated with anti-c-Jun antibody Reference Product PubMed Publications FOS antibody >8726 publications with c-Jun and FOS MAPK8 antibody >920 publications with c-Jun and MAPK8 FOSB antibody >371 publications with c-Jun and FOSB ATF3 antibody >262 publications with c-Jun and ATF3 MAPK1 antibody >240 publications with c-Jun and MAPK1 FOSL2 antibody >116 publications with c-Jun and FOSL2 NFATC2 antibody >51 publications with c-Jun and NFATC2 FOSL1 antibody >31 publications with c-Jun and FOSL1 MAPK9 antibody >17 publications with c-Jun and MAPK9 MAPK10 antibody >10 publications with c-Jun and MAPK10 Pathways associated with anti-c-Jun antibody Products by Pathway Pathway Diagram AGE-RAGE Signaling Pathway In Diabetic Complications antibodies AGE-RAGE Signaling Pathway In Diabetic Complications Diagram AGE-RAGE Signaling Pathway In Diabetic Complications antibodies AGE-RAGE Signaling Pathway In Diabetic Complications Diagram AGE/RAGE Pathway antibodies AGE/RAGE Pathway Diagram ATF-2 Transcription Factor Network Pathway antibodies ATF-2 Transcription Factor Network Pathway Diagram ATM Signaling Pathway antibodies ATM Signaling Pathway Diagram Activated TLR4 Signalling Pathway antibodies Activated TLR4 Signalling Pathway Diagram Activation Of HOX Genes During Differentiation Pathway antibodies Activation Of HOX Genes During Differentiation Pathway Diagram Activation Of Anterior HOX Genes In Hindbrain Development During Early Embryogenesis Pathway antibodies Activation Of Anterior HOX Genes In Hindbrain Development During Early Embryogenesis Pathway Diagram Activation Of The AP-1 Family Of Transcription Factors Pathway antibodies Activation Of The AP-1 Family Of Transcription Factors Pathway Diagram Amphetamine Addiction Pathway antibodies Amphetamine Addiction Pathway Diagram Diseases associated with anti-c-Jun antibody Disease Name Pubmed Publications Nervous System Diseases Antibodies >199075 publications with c-Jun and Nervous System Diseases Brain Diseases Antibodies >99198 publications with c-Jun and Brain Diseases Heart Diseases Antibodies >94069 publications with c-Jun and Heart Diseases Pain Antibodies >64101 publications with c-Jun and Pain Inflammation Antibodies >52936 publications with c-Jun and Inflammation Liver Diseases Antibodies >50561 publications with c-Jun and Liver Diseases Kidney Diseases Antibodies >42883 publications with c-Jun and Kidney Diseases Hypertension Antibodies >39525 publications with c-Jun and Hypertension Necrosis Antibodies >33226 publications with c-Jun and Necrosis Hemorrhage Antibodies >32206 publications with c-Jun and Hemorrhage Organs/Tissues associated with anti-c-Jun antibody Organ/Tissue Name Pubmed Publications Blood Antibodies >340404 publications with c-Jun and Blood Brain Antibodies >145346 publications with c-Jun and Brain Heart Antibodies >113988 publications with c-Jun and Heart Vascular Antibodies >103021 publications with c-Jun and Vascular Bone Antibodies >99156 publications with c-Jun and Bone Liver Antibodies >88634 publications with c-Jun and Liver Muscle Antibodies >85388 publications with c-Jun and Muscle Lung Antibodies >69440 publications with c-Jun and Lung Kidney Antibodies >65558 publications with c-Jun and Kidney Skin Antibodies >63058 publications with c-Jun and Skin TOP © 2006-24 MyBioSource.com. 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