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anti-MYC antibody :: Rabbit c-myc HRP Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS194208 anti-MYC antibody
Unit / Price
0.1 mg  /  $350 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

c-myc HRP, Polyclonal Antibody

 Also Known As   

c-myc Affinity Purified Antibody, HRP Conjugated

 Product Synonym Names    c-myc HRP
 Product Gene Name   

anti-MYC antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 8; NC_000008.10 (128748315..128753680). Location: 8q24.21
 3D Structure    ModBase 3D Structure for Q6LBK7
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 Clonality    Polyclonal
 Host    Rabbit
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 Specificity    c-myc HRP [Rabbit polyclonal antibody to c-myc HRP Conjugate]
 Concentration    1 mg/ml (lot specific)
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 Antigen    c-myc (EQKLISEEDL) coupled to KLH.
 Buffer    50mM HEPES, pH 7.1, 0.1M NaCl
 Stabilizer    0.2% BSA
 Preservatives    0.01% thimerosal
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 Preparation and Storage    Store at 4 degree C; stable for one year
 Other Notes    Small volumes of anti-MYC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-MYC antibody    Epitope Tag Antibodies
 Applications Tested/Suitable for anti-MYC antibody   

ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry

 Application Notes for anti-MYC antibody    ELISA: 0.01 - 0.1 ug/ml
Western Blot: Colorimetric: 0.1-1 ug/ml, Chemiluminescent: 0.03-1 ug/ml
Immunohistochemistry/Immunocytochemistry: 0.5-2 ug/ml
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NCBI/Uniprot data below describe general gene information for MYC. It may not necessarily be applicable to this product.
 NCBI GI #    396512
 NCBI GeneID    4609
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 UniProt Primary Accession #    Q6LBK7 [Other Products]
 UniProt Related Accession #    P01106; Q14899; Q14901; Q16591; Q6LBK7; Q7KZ54 [Other Products]
 Molecular Weight    7,012 Da [Similar Products]
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 NCBI Official Full Name    c-myc
 NCBI Official Synonym Full Names    v-myc myelocytomatosis viral oncogene homolog (avian)
 NCBI Official Symbol    MYC [Similar Products]
 NCBI Official Synonym Symbols   
MRTL; c-Myc; bHLHe39
[Similar Products]
 NCBI Protein Information    myc proto-oncogene protein; OTTHUMP00000158589; OTTHUMP00000227763; proto-oncogene c-Myc; transcription factor p64; class E basic helix-loop-helix protein 39; avian myelocytomatosis viral oncogene homolog; v-myc avian myelocytomatosis viral oncogene homolog; myc-related translation/localization regulatory factor
 UniProt Protein Name    C-myc protein
 Protein Family    Myc protein
 UniProt Gene Name    c-myc [Similar Products]
 UniProt Entry Name    Q6LBK7_HUMAN
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 NCBI Summary for MYC    The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq]
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 UniProt Comments for MYC    Myc: a proto-oncogenic transcription factor that plays a role in cell proliferation, apoptosis and in the development of human tumors. Seems to activate the transcription of growth-related genes.

Protein type: Nucleolus; Oncoprotein; Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 8q24.21

Cellular Component: nucleoplasm; protein complex; nucleolus; nucleus; cytosol

Molecular Function: protein dimerization activity; protein binding; DNA binding; protein complex binding; transcription factor binding; transcription factor activity

Biological Process: cellular iron ion homeostasis; oxygen transport; positive regulation of transcription, DNA-dependent; positive regulation of caspase activity; Wnt receptor signaling pathway through beta-catenin; negative regulation of transcription from RNA polymerase II promoter; chromosome organization and biogenesis; positive regulation of fibroblast proliferation; transforming growth factor beta receptor signaling pathway; positive regulation of mesenchymal cell proliferation; positive regulation of cell proliferation; response to gamma radiation; cell cycle arrest; response to drug; transcription initiation from RNA polymerase II promoter; Notch signaling pathway; regulation of telomere maintenance; transcription, DNA-dependent; MAPKKK cascade; negative regulation of cell division; negative regulation of monocyte differentiation; negative regulation of stress-activated MAPK cascade; chromatin remodeling; regulation of gene expression; ureteric bud branching; negative regulation of fibroblast proliferation; energy reserve metabolic process; gene expression; positive regulation of transcription from RNA polymerase II promoter; response to DNA damage stimulus; positive regulation of epithelial cell proliferation; negative regulation of apoptosis

Disease: Burkitt Lymphoma
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 Research Articles on MYC    1. MYC amplification is a prognostic marker of patients with early-stage lung adenocarcinoma
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-MYC antibodyPathways associated with anti-MYC antibody
 Reference Product  PubMed Publications
 MAX antibody  >892 publications with MYC and MAX
 CDKN1A antibody  >458 publications with MYC and CDKN1A
 CDKN2A antibody  >378 publications with MYC and CDKN2A
 BCL2 antibody  >287 publications with MYC and BCL2
 SP1 antibody  >256 publications with MYC and SP1
 CDK4 antibody  >227 publications with MYC and CDK4
 E2F1 antibody  >211 publications with MYC and E2F1
 BRCA1 antibody  >112 publications with MYC and BRCA1
 MXI1 antibody  >107 publications with MYC and MXI1
 MAPK3 antibody  >98 publications with MYC and MAPK3
 Products by Pathway  Pathway Diagram
 Acute Myeloid Leukemia Pathway antibodies  Acute Myeloid Leukemia Pathway Diagram
 Acute Myeloid Leukemia Pathway antibodies  Acute Myeloid Leukemia Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Bladder Cancer Pathway antibodies  Bladder Cancer Pathway Diagram
 Bladder Cancer Pathway antibodies  Bladder Cancer Pathway Diagram
 C-MYB Transcription Factor Network Pathway antibodies  C-MYB Transcription Factor Network Pathway Diagram
 C-MYC Pathway antibodies  C-MYC Pathway Diagram
 CD40/CD40L Signaling Pathway antibodies  CD40/CD40L Signaling Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
Diseases associated with anti-MYC antibodyOrgans/Tissues associated with anti-MYC antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >13089 publications with MYC and Neoplasms
 Carcinoma Antibodies  >3240 publications with MYC and Carcinoma
 Cell Transformation, Neoplastic Antibodies  >2340 publications with MYC and Cell Transformation, Neoplastic
 Neoplasms, Experimental Antibodies  >2016 publications with MYC and Neoplasms, Experimental
 Neuroectodermal Tumors Antibodies  >1972 publications with MYC and Neuroectodermal Tumors
 Neuroblastoma Antibodies  >1390 publications with MYC and Neuroblastoma
 Adenocarcinoma Antibodies  >1373 publications with MYC and Adenocarcinoma
 Skin Diseases Antibodies  >1285 publications with MYC and Skin Diseases
 Disease Models, Animal Antibodies  >1235 publications with MYC and Disease Models, Animal
 Breast Neoplasms Antibodies  >1198 publications with MYC and Breast Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2925 publications with MYC and Blood
 Liver Antibodies  >1585 publications with MYC and Liver
 Lung Antibodies  >1146 publications with MYC and Lung
 Bone Antibodies  >1065 publications with MYC and Bone
 Muscle Antibodies  >955 publications with MYC and Muscle
 Brain Antibodies  >899 publications with MYC and Brain
 Bone Marrow Antibodies  >774 publications with MYC and Bone Marrow
 Kidney Antibodies  >719 publications with MYC and Kidney
 Vascular Antibodies  >709 publications with MYC and Vascular
 Embryonic Tissue Antibodies  >535 publications with MYC and Embryonic Tissue
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