NP_061060.3
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
chondroitin sulfate N-acetylgalactosaminyltransferase 2
NCBI Official Synonym Full Names
chondroitin sulfate N-acetylgalactosaminyltransferase 2
NCBI Official Synonym Symbols
CHGN2; PRO0082; GALNACT2; GALNACT-2 [Similar Products]
NCBI Protein Information
chondroitin sulfate N-acetylgalactosaminyltransferase 2; beta 4 GalNAcT-2; chondroitin beta1,4 N-acetylgalactosaminyltransferase 2
UniProt Protein Name
Chondroitin sulfate N-acetylgalactosaminyltransferase 2
UniProt Synonym Protein Names
Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2; Beta4GalNAcT-2; GalNAcT-2
UniProt Synonym Gene Names
UniProt Entry Name
CGAT2_HUMAN
NCBI Summary for CSGALNACT2
This gene encodes a member of the chondroitin N-acetylgalactosaminyltransferase family. The encoded protein is involved in elongation during chondroitin sulfate synthesis. A related pseudogene has been identified on chromosome X. [provided by RefSeq, Dec 2012]
UniProt Comments for CSGALNACT2
GALNACT2: Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP- GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. Belongs to the chondroitin N- acetylgalactosaminyltransferase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transferase; Membrane protein, integral; Glycan Metabolism - chondroitin sulfate biosynthesis; EC 2.4.1.174
Chromosomal Location of Human Ortholog: 10q11.21
Cellular Component: Golgi membrane; membrane; integral to Golgi membrane
Molecular Function: metal ion binding; acetylgalactosaminyltransferase activity; glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity
Biological Process: chondroitin sulfate metabolic process; dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; chondroitin sulfate biosynthetic process; glycosaminoglycan metabolic process; proteoglycan biosynthetic process; chondroitin sulfate proteoglycan biosynthetic process; carbohydrate metabolic process; pathogenesis; chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; dermatan sulfate proteoglycan biosynthetic process
Research Articles on CSGALNACT2
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Products associated with anti-CSGALNACT2 antibody
Pathways associated with anti-CSGALNACT2 antibody
Organs/Tissues associated with anti-CSGALNACT2 antibody
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