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anti-CRYBB3 antibody :: Rabbit crystallin, beta B3 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS711067 anti-CRYBB3 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

crystallin, beta B3 (CRYBB3), Polyclonal Antibody

 Also Known As   

Rabbit anti-human crystallin, beta B3 polyclonal Antibody

 Product Synonym Names    crystallin; beta B3; CRYBB3; CATCN2; CRYB3; MGC125772; MGC125773; MGC125774Beta-B3 crystallin; Beta-crystallin B3
 Product Gene Name   

anti-CRYBB3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    gene 609741
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human CRYBB3
 Storage Buffer    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-22412 / sc-22413
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-CRYBB3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-CRYBB3 antibody   

ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)

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NCBI/Uniprot data below describe general gene information for CRYBB3. It may not necessarily be applicable to this product.
 NCBI GI #    77567630
 NCBI GeneID    1417
 NCBI Accession #    AAI07483.1 [Other Products]
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 UniProt Secondary Accession #    Q3B7S9; Q3T1B7; Q6ISK6; Q92965; Q9UH09 [Other Products]
 UniProt Related Accession #    P26998 [Other Products]
 Molecular Weight    24,252 Da [Similar Products]
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 NCBI Official Full Name    Crystallin, beta B3
 NCBI Official Synonym Full Names    crystallin, beta B3
 NCBI Official Symbol    CRYBB3 [Similar Products]
 NCBI Official Synonym Symbols   
CRYB3; CATCN2; CTRCT22
[Similar Products]
 NCBI Protein Information    beta-crystallin B3; eye lens structural protein
 UniProt Protein Name    Beta-crystallin B3
 UniProt Synonym Protein Names   
Beta-B3 crystallinCleaved into the following chain:Beta-crystallin B3, N-terminally processed
 Protein Family    Beta-crystallin
 UniProt Gene Name    CRYBB3 [Similar Products]
 UniProt Synonym Gene Names    CRYB3 [Similar Products]
 UniProt Entry Name    CRBB3_HUMAN
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 NCBI Summary for CRYBB3    Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta basic group member, is part of a gene cluster with beta-A4, beta-B1, and beta-B2. Mutations in this gene result in cataract congenital nuclear autosomal recessive type 2. [provided by RefSeq, Feb 2013]
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 UniProt Comments for CRYBB3    CRYBB3: a major structural protein of the eye lens. A member of the beta/gamma-crystallin family.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 22q11.23

Molecular Function: structural constituent of eye lens

Biological Process: visual perception

Disease: Cataract 22, Multiple Types
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 Research Articles on CRYBB3    1. For the first time, a mutation in CRYBB3 is reported in two consanguineous Pakistani families with autosomal recessive congenital cataracts.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CRYBB3 antibodyDiseases associated with anti-CRYBB3 antibody
 Reference Product  PubMed Publications
 CRYBB2 antibody  >20 publications with CRYBB3 and CRYBB2
 CRYBA1 antibody  >12 publications with CRYBB3 and CRYBA1
 CRYAA antibody  >10 publications with CRYBB3 and CRYAA
 CRYAB antibody  >9 publications with CRYBB3 and CRYAB
 GJA8 antibody  >8 publications with CRYBB3 and GJA8
 GJA3 antibody  >6 publications with CRYBB3 and GJA3
 CRYBA2 antibody  >5 publications with CRYBB3 and CRYBA2
 BFSP1 antibody  >2 publications with CRYBB3 and BFSP1
 TMEM114 antibody  >1 publications with CRYBB3 and TMEM114
 Disease Name  Pubmed Publications
 Muscular Diseases Antibodies  >1 publications with CRYBB3 and Muscular Diseases
 Disease Models, Animal Antibodies  >1 publications with CRYBB3 and Disease Models, Animal
Organs/Tissues associated with anti-CRYBB3 antibody
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >19 publications with CRYBB3 and Eye
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