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anti-Defb1 antibody :: Goat defensin, beta 1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS422721 anti-Defb1 antibody
Unit / Price
0.1 mg  /  $225 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

defensin, beta 1 (Defb1), Polyclonal Antibody

★Popular Item★
 Also Known As   

Goat anti-defensin, beta 1 (mouse) Antibody

 Product Synonym Names    Defb1; defensin beta 1; AL590630.1; AW260221; BD-1; beta-defensin 1; AL590630.1 antibody; BD-1 antibody; defensin beta 1 antibody; AW260221 antibody; beta-defensin 1 antibody; Defb1 antibody; Defensin, beta 1; defensin, beta 1 (mouse)
 Product Gene Name   

anti-Defb1 antibody

[Similar Products]
 Antibody/Peptide Pairs    defensin, beta 1 peptide (MBS427558) is used for blocking the activity of defensin, beta 1 antibody (MBS422721)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    TKLQGTCKPD KPN
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 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Expected from sequence similarity: Mouse, Rat
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 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
 Concentration    100ug specific antibody in 200ul (lot specific)
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 Immunogen    Peptide with sequence TKLQGTCKPDKPN, from the C Terminus of the protein sequence according to NP_031869.1.
 Epitope    C Terminus
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 Preparation and Storage    Aliquot and store at -20 degree C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-Defb1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-Defb1 antibody   

Peptide ELISA (EIA)

 Application Notes for anti-Defb1 antibody    Peptide ELISA: Antibody detection limit dilution 1: 4000.
Western Blot: Not yet tested - our routinely used western blotting protocol does not allow detection of proteins as small as the calculated size of 7.75kDa according to NP_031869.1. Therefore we cannot recommend an optimal concentration and the antibody is an aspiring product.
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NCBI/Uniprot data below describe general gene information for Defb1. It may not necessarily be applicable to this product.
 NCBI GI #    6681161
 NCBI GeneID    13214
 NCBI Accession #    NP_031869.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_007843.3 [Other Products]
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 UniProt Related Accession #    P56386 [Other Products]
 Molecular Weight    7,749 Da
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 NCBI Official Full Name    beta-defensin 1
 NCBI Official Synonym Full Names    defensin beta 1
 NCBI Official Symbol    Defb1 [Similar Products]
 NCBI Official Synonym Symbols   
BD-1; AW260221
[Similar Products]
 NCBI Protein Information    beta-defensin 1
 UniProt Protein Name    Beta-defensin 1
 UniProt Synonym Protein Names   
Defensin, beta 1
 Protein Family    Beta-defensin
 UniProt Gene Name    Defb1 [Similar Products]
 UniProt Synonym Gene Names    BD-1; mBD-1 [Similar Products]
 UniProt Entry Name    DEFB1_MOUSE
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 UniProt Comments for Defb1    defensin, beta 1: Has bactericidal activity. Belongs to the beta-defensin family.

Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Cellular Component: extracellular region; extracellular space

Biological Process: defense response; defense response to bacterium; innate immune response; response to bacterium
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 Research Articles on Defb1    1. Fenofibrate and gemfibrozil inhibit LPS-induced inflammatory activation of macrophages via PPARalpha/beta-defensin 1/TLR4 pathway.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-Defb1 antibodyDiseases associated with anti-Defb1 antibody
 Products by Pathway  Pathway Diagram
 Beta Defensins Pathway antibodies  Beta Defensins Pathway Diagram
 Defensins Pathway antibodies  Defensins Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >69 publications with Defb1 and Inflammation
 Immune System Diseases Antibodies  >47 publications with Defb1 and Immune System Diseases
 Necrosis Antibodies  >37 publications with Defb1 and Necrosis
 Lung Diseases Antibodies  >33 publications with Defb1 and Lung Diseases
 Carcinoma Antibodies  >24 publications with Defb1 and Carcinoma
 Fibrosis Antibodies  >18 publications with Defb1 and Fibrosis
 Kidney Diseases Antibodies  >9 publications with Defb1 and Kidney Diseases
 Precancerous Conditions Antibodies  >5 publications with Defb1 and Precancerous Conditions
 Neoplasms, Experimental Antibodies  >4 publications with Defb1 and Neoplasms, Experimental
 Prostatic Neoplasms Antibodies  >4 publications with Defb1 and Prostatic Neoplasms
Organs/Tissues associated with anti-Defb1 antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >80 publications with Defb1 and Blood
 Kidney Antibodies  >31 publications with Defb1 and Kidney
 Embryonic Tissue Antibodies  >16 publications with Defb1 and Embryonic Tissue
 Uterus Antibodies  >13 publications with Defb1 and Uterus
 Eye Antibodies  >8 publications with Defb1 and Eye
 Heart Antibodies  >6 publications with Defb1 and Heart
 Prostate Antibodies  >6 publications with Defb1 and Prostate
 Pancreas Antibodies  >2 publications with Defb1 and Pancreas
 Thymus Antibodies  >1 publications with Defb1 and Thymus
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