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anti-EFNB1 antibody :: Rabbit ephrin-B1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS714590 anti-EFNB1 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ephrin-B1 (EFNB1), Polyclonal Antibody

 Also Known As   

Rabbit anti-human ephrin-B1 polyclonal Antibody

 Product Synonym Names    ephrin-B1; EFNB1; CFND; CFNS; EFL3; EPLG2; Elk-L; LERK2; MGC8782
 Product Gene Name   

anti-EFNB1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    gene 304110
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human EFNB1
 Storage Buffer    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-20723 / sc-1011 / sc-910
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-EFNB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-EFNB1 antibody   

ELISA (EIA), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for EFNB1. It may not necessarily be applicable to this product.
 NCBI GI #    4758248
 NCBI GeneID    1947
 NCBI Accession #    NP_004420.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_004429.4 [Other Products]
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 UniProt Secondary Accession #    D3DVU0 [Other Products]
 UniProt Related Accession #    P98172 [Other Products]
 Molecular Weight    38,007 Da [Similar Products]
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 NCBI Official Full Name    ephrin-B1
 NCBI Official Synonym Full Names    ephrin-B1
 NCBI Official Symbol    EFNB1 [Similar Products]
 NCBI Official Synonym Symbols   
CFND; CFNS; EFB1; EFL3; EPLG2; Elk-L; LERK2
[Similar Products]
 NCBI Protein Information    ephrin-B1; EFL-3; LERK-2; ELK ligand; ligand of eph-related kinase 2; eph-related receptor tyrosine kinase ligand 2
 UniProt Protein Name    Ephrin-B1
 UniProt Synonym Protein Names   
EFL-3; ELK ligand; ELK-L; EPH-related receptor tyrosine kinase ligand 2; LERK-2
 Protein Family    Ephrin
 UniProt Gene Name    EFNB1 [Similar Products]
 UniProt Synonym Gene Names    EFL3; EPLG2; LERK2; ELK-L; LERK-2 [Similar Products]
 UniProt Entry Name    EFNB1_HUMAN
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 NCBI Summary for EFNB1    The protein encoded by this gene is a type I membrane protein and a ligand of Eph-related receptor tyrosine kinases. It may play a role in cell adhesion and function in the development or maintenance of the nervous system. [provided by RefSeq, Jul 2008]
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 UniProt Comments for EFNB1    EFNB1: a type I membrane protein of the ephrin family. A ligand of Eph-related receptor tyrosine kinases EphB1 and EphA1. Ephrins and ephrin receptors mediate numerous developmental processes, particularly in the nervous system. Ephrin-B1 may play a role in cell adhesion and functions in the development or maintenance of the nervous system. Binding to its receptor induces the collapse of commissural axons/growth cones in vitro. Induced by TNF-alpha. Expressed in brain, heart, placenta, lung, liver, skeletal muscle, kidney, and pancreas.

Protein type: Membrane protein, integral; Ligand, receptor tyrosine kinase

Chromosomal Location of Human Ortholog: Xq12

Cellular Component: integral to plasma membrane; cytoplasm; plasma membrane; synapse; nucleus; lipid raft

Molecular Function: protein binding; ephrin receptor binding

Biological Process: axon guidance; cell-cell signaling; ephrin receptor signaling pathway; positive regulation of T cell proliferation; cell adhesion; embryonic pattern specification; neural crest cell migration

Disease: Craniofrontonasal Syndrome
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 Research Articles on EFNB1    1. CNK1 mediates ephrinB1 signaling that promotes cell migration through RhoA and JNK activity.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-EFNB1 antibodyPathways associated with anti-EFNB1 antibody
 Reference Product  PubMed Publications
 EPHB2 antibody  >12 publications with EFNB1 and EPHB2
 EPHB1 antibody  >9 publications with EFNB1 and EPHB1
 EPHB3 antibody  >3 publications with EFNB1 and EPHB3
 EPHB6 antibody  >3 publications with EFNB1 and EPHB6
 SRC antibody  >3 publications with EFNB1 and SRC
 PTPN13 antibody  >2 publications with EFNB1 and PTPN13
 RGS3 antibody  >1 publications with EFNB1 and RGS3
 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 EPH-Ephrin Signaling Pathway antibodies  EPH-Ephrin Signaling Pathway Diagram
 EPH-ephrin Mediated Repulsion Of Cells Pathway antibodies  EPH-ephrin Mediated Repulsion Of Cells Pathway Diagram
 EPHB Forward Signaling Pathway antibodies  EPHB Forward Signaling Pathway Diagram
 EPHB-mediated Forward Signaling Pathway antibodies  EPHB-mediated Forward Signaling Pathway Diagram
 Ephrin B Reverse Signaling Pathway antibodies  Ephrin B Reverse Signaling Pathway Diagram
 Ephrin Signaling Pathway antibodies  Ephrin Signaling Pathway Diagram
Diseases associated with anti-EFNB1 antibodyOrgans/Tissues associated with anti-EFNB1 antibody
 Disease Name  Pubmed Publications
 Craniosynostoses Antibodies  >16 publications with EFNB1 and Craniosynostoses
 Hypertelorism Antibodies  >12 publications with EFNB1 and Hypertelorism
 Frontonasal dysplasia Antibodies  >8 publications with EFNB1 and Frontonasal dysplasia
 Craniofrontonasal dysplasia Antibodies  >7 publications with EFNB1 and Craniofrontonasal dysplasia
 Nervous System Diseases Antibodies  >7 publications with EFNB1 and Nervous System Diseases
 Abnormalities, Multiple Antibodies  >5 publications with EFNB1 and Abnormalities, Multiple
 Inflammation Antibodies  >4 publications with EFNB1 and Inflammation
 Necrosis Antibodies  >3 publications with EFNB1 and Necrosis
 Brain Diseases Antibodies  >3 publications with EFNB1 and Brain Diseases
 Neurobehavioral Manifestations Antibodies  >2 publications with EFNB1 and Neurobehavioral Manifestations
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >20 publications with EFNB1 and Brain
 Bone Antibodies  >18 publications with EFNB1 and Bone
 Embryonic Tissue Antibodies  >8 publications with EFNB1 and Embryonic Tissue
 Vascular Antibodies  >7 publications with EFNB1 and Vascular
 Connective Tissue Antibodies  >4 publications with EFNB1 and Connective Tissue
 Muscle Antibodies  >4 publications with EFNB1 and Muscle
 Spleen Antibodies  >3 publications with EFNB1 and Spleen
 Eye Antibodies  >3 publications with EFNB1 and Eye
 Ovary Antibodies  >2 publications with EFNB1 and Ovary
 Kidney Antibodies  >2 publications with EFNB1 and Kidney
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