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anti-EIF3M antibody :: Rabbit eukaryotic translation initiation factor 3, subunit M Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS714971 anti-EIF3M antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

eukaryotic translation initiation factor 3, subunit M (EIF3M), Polyclonal Antibody

 Also Known As   

Rabbit anti-human eukaryotic translation initiation factor 3, subunit M polyclonal Antibody

 Product Synonym Names    eukaryotic translation initiation factor 3; subunit M; EIF3M; B5; FLJ29030; GA17; PCID1; hfl-B5
 Product Gene Name   

anti-EIF3M antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    609641
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human EIF3M
 Storage Buffer    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-133541
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-EIF3M antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-EIF3M antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

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NCBI/Uniprot data below describe general gene information for EIF3M. It may not necessarily be applicable to this product.
 NCBI GI #    23397429
 NCBI GeneID    10480
 NCBI Accession #    NP_006351.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_006360.4 [Other Products]
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 UniProt Secondary Accession #    O60735; Q2F836; Q53HL6; Q9BXW1; A8K7X4; B4E2Q4 [Other Products]
 UniProt Related Accession #    Q7L2H7 [Other Products]
 Molecular Weight    27,865 Da [Similar Products]
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 NCBI Official Full Name    eukaryotic translation initiation factor 3 subunit M
 NCBI Official Synonym Full Names    eukaryotic translation initiation factor 3, subunit M
 NCBI Official Symbol    EIF3M [Similar Products]
 NCBI Official Synonym Symbols   
B5; GA17; PCID1; TANGO7; hfl-B5
[Similar Products]
 NCBI Protein Information    eukaryotic translation initiation factor 3 subunit M; EIF3M; B5 receptor; fetal lung protein B5; dendritic cell protein; PCI domain-containing protein 1; transport and golgi organization 7 homolog; PCI domain containing 1 (herpesvirus entry mediator)
 UniProt Protein Name    Eukaryotic translation initiation factor 3 subunit M
 UniProt Synonym Protein Names   
Fetal lung protein B5; hFL-B5; PCI domain-containing protein 1
 UniProt Gene Name    EIF3M [Similar Products]
 UniProt Synonym Gene Names    ; hFL-B5 [Similar Products]
 UniProt Entry Name    EIF3M_HUMAN
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 NCBI Summary for EIF3M    This gene encodes a protein that is part of the eurkaryotic translation initiation factor 3 complete (eIF-3) required for protein synthesis. Elevated levels of the encoded protein are present in cancer cell lines. Inactivation of the encoded protein has been shown to interfere with translation of herpes virus mRNAs by preventing the association of mRNAs with the ribosomes. A pseudogene of this gene is located on the X chromosome. [provided by RefSeq, Dec 2011]
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 UniProt Comments for EIF3M    EIF3M: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. May favor virus entry in case of infection with herpes simplex virus 1 (HSV1) or herpes simplex virus 2 (HSV2). Belongs to the eIF-3 subunit M family.

Protein type: Translation initiation

Chromosomal Location of Human Ortholog: 11p13

Cellular Component: eukaryotic translation initiation factor 3 complex

Molecular Function: protein binding; translation initiation factor binding; translation initiation factor activity

Biological Process: translational initiation; formation of translation preinitiation complex; regulation of translational initiation
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 Research Articles on EIF3M    1. POLR2J interacts with three different subunits of eIF3, eIF3a, eIF3i, and eIF3m.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-EIF3M antibodyOrgans/Tissues associated with anti-EIF3M antibody
 Reference Product  PubMed Publications
 EIF3E antibody  >10 publications with EIF3M and EIF3E
 EIF3A antibody  >4 publications with EIF3M and EIF3A
 EIF3I antibody  >2 publications with EIF3M and EIF3I
 EIF3G antibody  >2 publications with EIF3M and EIF3G
 EIF3F antibody  >2 publications with EIF3M and EIF3F
 EIF3H antibody  >2 publications with EIF3M and EIF3H
 EIF3B antibody  >1 publications with EIF3M and EIF3B
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >1 publications with EIF3M and Liver
 Uncharacterized Tissue Antibodies  >1 publications with EIF3M and Uncharacterized Tissue
 Lung Antibodies  >1 publications with EIF3M and Lung
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