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anti-FZD9 antibody :: Rabbit frizzled homolog 9 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS716474 anti-FZD9 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

frizzled homolog 9 (FZD9), Polyclonal Antibody

 Also Known As   

Rabbit anti-human frizzled homolog 9 (Drosophila) polyclonal Antibody

 Product Synonym Names    frizzled homolog 9 (Drosophila); FZD9; CD349; FZD3
 Product Gene Name   

anti-FZD9 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    601766
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human FZD9
 Storage Buffer    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-33506 / sc-33508 / sc-33509
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-FZD9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-FZD9 antibody   

ELISA (EIA), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for FZD9. It may not necessarily be applicable to this product.
 NCBI GI #    4503835
 NCBI GeneID    8326
 NCBI Accession #    NP_003499.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_003508.2 [Other Products]
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 UniProt Related Accession #    O00144 [Other Products]
 Molecular Weight    64,466 Da [Similar Products]
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 NCBI Official Full Name    frizzled-9
 NCBI Official Synonym Full Names    frizzled class receptor 9
 NCBI Official Symbol    FZD9 [Similar Products]
 NCBI Official Synonym Symbols   
FZD3; CD349
[Similar Products]
 NCBI Protein Information    frizzled-9; fz-9; fzE6; hFz9; frizzled homolog 9; frizzled family receptor 9; frizzled 9, seven transmembrane spanning receptor
 UniProt Protein Name    Frizzled-9
 UniProt Synonym Protein Names   
FzE6; CD_antigen: CD349
 Protein Family    Frizzled
 UniProt Gene Name    FZD9 [Similar Products]
 UniProt Synonym Gene Names    FZD3; Fz-9; hFz9 [Similar Products]
 UniProt Entry Name    FZD9_HUMAN
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 NCBI Summary for FZD9    Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD9 gene is located within the Williams syndrome common deletion region of chromosome 7, and heterozygous deletion of the FZD9 gene may contribute to the Williams syndrome phenotype. FZD9 is expressed predominantly in brain, testis, eye, skeletal muscle, and kidney. [provided by RefSeq, Jul 2008]
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 UniProt Comments for FZD9    FZD9: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK- 3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Belongs to the G-protein coupled receptor Fz/Smo family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; GPCR, Fz/Smo family; Receptor, GPCR

Chromosomal Location of Human Ortholog: 7q11.23

Cellular Component: filopodium membrane; cell surface; perinuclear region of cytoplasm; cytoplasm; integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; Wnt-protein binding; Wnt receptor activity; protein homodimerization activity; protein heterodimerization activity

Biological Process: G-protein coupled receptor protein signaling pathway; nervous system development; learning and/or memory; B cell differentiation; neuroblast proliferation; Wnt receptor signaling pathway through beta-catenin
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 Research Articles on FZD9    1. The activity of the Sprouty4 promoter is increased by Wnt7A/Fzd9 signaling through peroxisome proliferator-activated receptor gamma in lung cancer cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-FZD9 antibodyPathways associated with anti-FZD9 antibody
 Reference Product  PubMed Publications
 WNT1 antibody  >6 publications with FZD9 and WNT1
 LRP6 antibody  >5 publications with FZD9 and LRP6
 WNT2 antibody  >5 publications with FZD9 and WNT2
 WNT2B antibody  >4 publications with FZD9 and WNT2B
 LRP5 antibody  >4 publications with FZD9 and LRP5
 WNT3A antibody  >4 publications with FZD9 and WNT3A
 WNT7A antibody  >4 publications with FZD9 and WNT7A
 WNT9A antibody  >2 publications with FZD9 and WNT9A
 WNT9B antibody  >1 publications with FZD9 and WNT9B
 Products by Pathway  Pathway Diagram
 Basal Cell Carcinoma Pathway antibodies  Basal Cell Carcinoma Pathway Diagram
 Basal Cell Carcinoma Pathway antibodies  Basal Cell Carcinoma Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Melanogenesis Pathway antibodies  Melanogenesis Pathway Diagram
 Melanogenesis Pathway antibodies  Melanogenesis Pathway Diagram
Diseases associated with anti-FZD9 antibodyOrgans/Tissues associated with anti-FZD9 antibody
 Disease Name  Pubmed Publications
 Respiratory Tract Diseases Antibodies  >5 publications with FZD9 and Respiratory Tract Diseases
 Disease Models, Animal Antibodies  >4 publications with FZD9 and Disease Models, Animal
 Inflammation Antibodies  >4 publications with FZD9 and Inflammation
 Growth Disorders Antibodies  >3 publications with FZD9 and Growth Disorders
 Liver Diseases Antibodies  >3 publications with FZD9 and Liver Diseases
 Death Antibodies  >3 publications with FZD9 and Death
 Breast Neoplasms Antibodies  >2 publications with FZD9 and Breast Neoplasms
 Atrophy Antibodies  >2 publications with FZD9 and Atrophy
 Memory Disorders Antibodies  >2 publications with FZD9 and Memory Disorders
 Learning Disorders Antibodies  >2 publications with FZD9 and Learning Disorders
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >16 publications with FZD9 and Brain
 Lung Antibodies  >6 publications with FZD9 and Lung
 Connective Tissue Antibodies  >4 publications with FZD9 and Connective Tissue
 Skin Antibodies  >2 publications with FZD9 and Skin
 Testis Antibodies  >2 publications with FZD9 and Testis
 Mixed Antibodies  >1 publications with FZD9 and Mixed
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