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anti-Lgals1 antibody :: Goat galectin-1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS422589
Western Blot (WB)
Unit / Price
0.1 mg  /  $300 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

galectin-1 (Lgals1), Polyclonal Antibody

 Also Known As   

Goat anti-galectin-1 (mouse) Antibody

 Product Synonym Names    Goat Anti-galectin-1 (mouse) (aa100-112) Antibody; Lgals1; lectin, galactose binding, soluble 1; AA410090; Gal-1; Galbp; L-14.5; L14; Lect14; galectin-1; 14 kDa lectin; S-Lac lectin 1; beta-galactoside binding protein; beta-galactoside-binding lectin L-14-I; galaptin; galectin-1; lactose-binding lectin 1; Lgals1 antibody; lectin; galactose binding; soluble 1 antibody; AA410090 antibody; Gal-1 antibody; Galbp antibody; L-14.5 antibody; L14 antibody; Lect14 antibody; galectin-1 antibody; S-Lac lectin 1 antibody; beta-galactoside binding protein antibody; beta-galactoside-binding lectin L-14-I antibody; galaptin antibody; galectin-1 antibody; lactose-binding lectin 1 antibody; Galectin-1; galectin-1 (mouse)
 Product Gene Name   

anti-Lgals1 antibody

[Similar Products]
 Antibody/Peptide Pairs    galectin-1 peptide (MBS428599) is used for blocking the activity of galectin-1 antibody (MBS422589)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    KPGECLKVRG EVASD
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 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Tested: Mouse, Rat; Expected from sequence similarity: Human, Mouse, Rat, Pig, Cow
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 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
 Concentration    100ug specific antibody in 200ul (lot specific)
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 Immunogen    Peptide with sequence KPGECLKVRGEVASD, from the N Terminus (near) of the protein sequence according to NP_032521.1.
 Epitope    N Terminus (near)
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 Preparation and Storage    Aliquot and store at -20 degree C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-Lgals1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-Lgals1 antibody   

Peptide ELISA (EIA), Western Blot (WB)

 Application Notes for anti-Lgals1 antibody    Peptide ELISA: Antibody detection limit dilution 1: 8000.
Western Blot: Approx 15kDa band observed in lysates of Mouse and Rat Pancreas and of cell line NIH3T3 (calculated MW of 14.9kDa according to NP_032521.1). Recommended concentration: 0.1-0.3ug/ml.
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 Western Blot (WB) of anti-Lgals1 antibody    (0.1ug/ml) staining of Mouse (A) and Rat (B) Pancreas lysates and NIH3T3 (C) lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
anti-Lgals1 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for Lgals1. It may not necessarily be applicable to this product.
 NCBI GI #    6678682
 NCBI GeneID    16852
 NCBI Accession #    NP_032521.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_008495.2 [Other Products]
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 UniProt Secondary Accession #    P05163; P11946; P17601; Q4FZH4; Q99M27; Q9D0X0 [Other Products]
 UniProt Related Accession #    P16045 [Other Products]
 Molecular Weight    14,866 Da
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 NCBI Official Full Name    galectin-1
 NCBI Official Synonym Full Names    lectin, galactose binding, soluble 1
 NCBI Official Symbol    Lgals1 [Similar Products]
 NCBI Official Synonym Symbols   
L14; Gal-1; Galbp; L-14.5; Lect14; AA410090; galectin-1
[Similar Products]
 NCBI Protein Information    galectin-1
 UniProt Protein Name    Galectin-1
 UniProt Synonym Protein Names   
14 kDa lectin; Beta-galactoside-binding lectin L-14-I; Galaptin; Lactose-binding lectin 1; Lectin galactoside-binding soluble 1; S-Lac lectin 1
 Protein Family    Galectin
 UniProt Gene Name    Lgals1 [Similar Products]
 UniProt Synonym Gene Names    Gbp; Gal-1 [Similar Products]
 UniProt Entry Name    LEG1_MOUSE
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 UniProt Comments for Lgals1    galectin-1: May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Homodimer. Binds LGALS3BP. Interacts with CD2, CD3, CD4, CD7, CD43 and CD45. Interacts with laminin (via poly-N- acetyllactosamine). Expressed in placenta, maternal decidua and fetal membranes. Within placenta, expressed in trophoblasts, stromal cells, villous endothelium, syncytiotrophoblast apical membrane and villous stroma. Within fetal membranes, expressed in amnion, chorioamniotic mesenchyma and chorion. Expressed in cardiac, smooth, and skeletal muscle, neurons, thymus, kidney and hematopoietic cells.

Protein type: Extracellular matrix; Cell adhesion; Secreted

Cellular Component: cell surface; cytoplasm; extracellular matrix; extracellular region; extracellular space; intracellular; nucleus; proteinaceous extracellular matrix

Molecular Function: carbohydrate binding; galactose binding; glycoprotein binding; lactose binding; laminin binding; protein binding; protein homodimerization activity; signal transducer activity

Biological Process: apoptosis; heterophilic cell adhesion; maintenance of protein localization; myoblast differentiation; plasma cell differentiation; positive regulation of erythrocyte aggregation; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of virion penetration into host cell; signal transduction; T cell costimulation
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 Research Articles on Lgals1    1. The authors found that exposure of HL-1 cardiac cells to Gal-1 reduced the percentage of infection by two different Trypanosoma cruzi strains, Tulahuen (TcVI) and Brazil (TcI).
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-Lgals1 antibodyPathways associated with anti-Lgals1 antibody
 Reference Product  PubMed Publications
 Jun antibody  >139 publications with Lgals1 and Jun
 Tdg antibody  >9 publications with Lgals1 and Tdg
 Trpv5 antibody  >6 publications with Lgals1 and Trpv5
 Gemin4 antibody  >4 publications with Lgals1 and Gemin4
 Kras antibody  >3 publications with Lgals1 and Kras
 Ptprc antibody  >2 publications with Lgals1 and Ptprc
 Anxa5 antibody  >2 publications with Lgals1 and Anxa5
 Pou2af1 antibody  >1 publications with Lgals1 and Pou2af1
 Tnc antibody  >1 publications with Lgals1 and Tnc
 Products by Pathway  Pathway Diagram
 PodNet: Protein-protein Interactions In The Podocyte Pathway antibodies  PodNet: Protein-protein Interactions In The Podocyte Pathway Diagram
 XPodNet - Protein-protein Interactions In The Podocyte Expanded By STRING Pathway antibodies  XPodNet - Protein-protein Interactions In The Podocyte Expanded By STRING Pathway Diagram
Diseases associated with anti-Lgals1 antibodyOrgans/Tissues associated with anti-Lgals1 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >146 publications with Lgals1 and Inflammation
 Neoplasm Metastasis Antibodies  >81 publications with Lgals1 and Neoplasm Metastasis
 Disease Models, Animal Antibodies  >78 publications with Lgals1 and Disease Models, Animal
 Adenocarcinoma Antibodies  >72 publications with Lgals1 and Adenocarcinoma
 Neoplasms, Experimental Antibodies  >54 publications with Lgals1 and Neoplasms, Experimental
 Breast Neoplasms Antibodies  >45 publications with Lgals1 and Breast Neoplasms
 Lung Neoplasms Antibodies  >37 publications with Lgals1 and Lung Neoplasms
 Necrosis Antibodies  >33 publications with Lgals1 and Necrosis
 Liver Diseases Antibodies  >25 publications with Lgals1 and Liver Diseases
 Kidney Diseases Antibodies  >24 publications with Lgals1 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >396 publications with Lgals1 and Blood
 Brain Antibodies  >102 publications with Lgals1 and Brain
 Muscle Antibodies  >73 publications with Lgals1 and Muscle
 Lung Antibodies  >59 publications with Lgals1 and Lung
 Liver Antibodies  >56 publications with Lgals1 and Liver
 Embryonic Tissue Antibodies  >53 publications with Lgals1 and Embryonic Tissue
 Kidney Antibodies  >48 publications with Lgals1 and Kidney
 Bone Marrow Antibodies  >40 publications with Lgals1 and Bone Marrow
 Heart Antibodies  >34 publications with Lgals1 and Heart
 Spleen Antibodies  >34 publications with Lgals1 and Spleen
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