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anti-GSTA1 antibody :: Rabbit glutathione S-transferase alpha 1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS712341 anti-GSTA1 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

glutathione S-transferase alpha 1 (GSTA1), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-human glutathione S-transferase alpha 1 polyclonal Antibody

 Product Synonym Names    glutathione S-transferase alpha 1; GSTA1; GST2; GSTA1-1; GTH1; MGC131939
 Product Gene Name   

anti-GSTA1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    138359
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human GSTA1
 Storage Buffer    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-GSTA1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-GSTA1 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

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NCBI/Uniprot data below describe general gene information for GSTA1. It may not necessarily be applicable to this product.
 NCBI GI #    83406048
 NCBI GeneID    2938
 NCBI Accession #    AAI10892.1 [Other Products]
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 UniProt Secondary Accession #    Q14750; Q5GHF8; Q5SZC1 [Other Products]
 UniProt Related Accession #    P08263 [Other Products]
 Molecular Weight    25,631 Da [Similar Products]
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 NCBI Official Full Name    Glutathione S-transferase alpha 1
 NCBI Official Synonym Full Names    glutathione S-transferase alpha 1
 NCBI Official Symbol    GSTA1 [Similar Products]
 NCBI Official Synonym Symbols   
GST2; GTH1; GSTA1-1
[Similar Products]
 NCBI Protein Information    glutathione S-transferase A1; GST-epsilon; GST HA subunit 1; GST, class alpha, 1; GST class-alpha member 1; glutathione S-transferase 2; glutathione S-aryltransferase A1; glutathione S-alkyltransferase A1; S-(hydroxyalkyl)glutathione lyase A1; glutathione S-transferase Ha subunit 1
 UniProt Protein Name    Glutathione S-transferase A1
 UniProt Synonym Protein Names   
GST HA subunit 1; GST class-alpha member 1; GST-epsilon; GSTA1-1; GTH1Cleaved into the following chain:Glutathione S-transferase A1, N-terminally processed
 Protein Family    Glutathione S-transferase
 UniProt Gene Name    GSTA1 [Similar Products]
 UniProt Entry Name    GSTA1_HUMAN
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 NCBI Summary for GSTA1    Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation. [provided by RefSeq, Jul 2008]
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 UniProt Comments for GSTA1    GSTA1: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Belongs to the GST superfamily. Alpha family.

Protein type: Other Amino Acids Metabolism - glutathione; EC 2.5.1.18; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Xenobiotic Metabolism - metabolism by cytochrome P450; Transferase

Chromosomal Location of Human Ortholog: 6p12.1

Cellular Component: cytosol

Molecular Function: glutathione transferase activity

Biological Process: glutathione metabolic process; epithelial cell differentiation; metabolic process; xenobiotic metabolic process
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 Research Articles on GSTA1    1. Combined GSTM1*0/GSTA1*A genotypes might be considered as genetic markers for cardiovascular death risk in ESRD patients, which may permit targeting of preventive and early intervention.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-GSTA1 antibodyPathways associated with anti-GSTA1 antibody
 Reference Product  PubMed Publications
 GSTA2 antibody  >48 publications with GSTA1 and GSTA2
 CYP2B6 antibody  >16 publications with GSTA1 and CYP2B6
 CYP3A4 antibody  >14 publications with GSTA1 and CYP3A4
 CYP1B1 antibody  >12 publications with GSTA1 and CYP1B1
 GPX1 antibody  >5 publications with GSTA1 and GPX1
 GSR antibody  >2 publications with GSTA1 and GSR
 Products by Pathway  Pathway Diagram
 4-hydroxy-2-nonenal Detoxification Pathway antibodies  4-hydroxy-2-nonenal Detoxification Pathway Diagram
 4-hydroxy-2-nonenal Detoxification Pathway antibodies  4-hydroxy-2-nonenal Detoxification Pathway Diagram
 AhR Pathway antibodies  AhR Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Drug Metabolism - Cytochrome P450 Pathway antibodies  Drug Metabolism - Cytochrome P450 Pathway Diagram
 Drug Metabolism - Cytochrome P450 Pathway antibodies  Drug Metabolism - Cytochrome P450 Pathway Diagram
 Glutathione Conjugation Pathway antibodies  Glutathione Conjugation Pathway Diagram
 Glutathione Metabolism Pathway antibodies  Glutathione Metabolism Pathway Diagram
Diseases associated with anti-GSTA1 antibodyOrgans/Tissues associated with anti-GSTA1 antibody
 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >31 publications with GSTA1 and Liver Diseases
 Breast Neoplasms Antibodies  >24 publications with GSTA1 and Breast Neoplasms
 Inflammation Antibodies  >21 publications with GSTA1 and Inflammation
 Liver Neoplasms Antibodies  >17 publications with GSTA1 and Liver Neoplasms
 Cardiovascular Diseases Antibodies  >12 publications with GSTA1 and Cardiovascular Diseases
 Urinary Bladder Neoplasms Antibodies  >10 publications with GSTA1 and Urinary Bladder Neoplasms
 Necrosis Antibodies  >9 publications with GSTA1 and Necrosis
 Carcinoma, Hepatocellular Antibodies  >9 publications with GSTA1 and Carcinoma, Hepatocellular
 Lung Neoplasms Antibodies  >9 publications with GSTA1 and Lung Neoplasms
 Neoplasms, Experimental Antibodies  >8 publications with GSTA1 and Neoplasms, Experimental
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >115 publications with GSTA1 and Liver
 Lung Antibodies  >32 publications with GSTA1 and Lung
 Kidney Antibodies  >26 publications with GSTA1 and Kidney
 Intestine Antibodies  >22 publications with GSTA1 and Intestine
 Heart Antibodies  >16 publications with GSTA1 and Heart
 Bladder Antibodies  >10 publications with GSTA1 and Bladder
 Prostate Antibodies  >9 publications with GSTA1 and Prostate
 Ovary Antibodies  >7 publications with GSTA1 and Ovary
 Brain Antibodies  >6 publications with GSTA1 and Brain
 Embryonic Tissue Antibodies  >5 publications with GSTA1 and Embryonic Tissue
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