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anti-GSTM5 antibody :: Rabbit glutathione S-transferase mu 5 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS712299 anti-GSTM5 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

glutathione S-transferase mu 5 (GSTM5), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-human glutathione S-transferase mu 5 polyclonal Antibody

 Product Synonym Names    glutathione S-transferase mu 5; GSTM5; GSTM5-5; GTM5
 Product Gene Name   

anti-GSTM5 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    138385
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human GSTM5
 Storage Buffer    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-GSTM5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-GSTM5 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

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NCBI/Uniprot data below describe general gene information for GSTM5. It may not necessarily be applicable to this product.
 NCBI GI #    23065563
 NCBI GeneID    2949
 NCBI Accession #    NP_000842.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000851.3 [Other Products]
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 UniProt Secondary Accession #    Q6PD78; A8K0V8 [Other Products]
 UniProt Related Accession #    P46439 [Other Products]
 Molecular Weight    25,675 Da [Similar Products]
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 NCBI Official Full Name    glutathione S-transferase Mu 5
 NCBI Official Synonym Full Names    glutathione S-transferase mu 5
 NCBI Official Symbol    GSTM5 [Similar Products]
 NCBI Official Synonym Symbols   
GTM5; GSTM5-5
[Similar Products]
 NCBI Protein Information    glutathione S-transferase Mu 5; GST class-mu 5; glutathione S-transferase M5; glutathione S-aryltransferase M5; glutathione S-alkyltransferase M5; glutathione S-aralkyltransferase M5; S-(hydroxyalkyl)glutathione lyase M5
 UniProt Protein Name    Glutathione S-transferase Mu 5
 UniProt Synonym Protein Names   
GST class-mu 5; GSTM5-5
 Protein Family    Glutathione S-transferase
 UniProt Gene Name    GSTM5 [Similar Products]
 UniProt Entry Name    GSTM5_HUMAN
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 NCBI Summary for GSTM5    Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. [provided by RefSeq, Jul 2008]
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 UniProt Comments for GSTM5    GSTM5: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Belongs to the GST superfamily. Mu family.

Protein type: EC 2.5.1.18; Other Amino Acids Metabolism - glutathione; Transferase; Xenobiotic Metabolism - metabolism by cytochrome P450; Xenobiotic Metabolism - drug metabolism - cytochrome P450

Chromosomal Location of Human Ortholog: 1p13.3

Cellular Component: cytosol

Molecular Function: glutathione transferase activity

Biological Process: glutathione metabolic process; xenobiotic metabolic process
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 Research Articles on GSTM5    1. The evidence presented suggests that GSTM1 and GSTM5 undergo epigenetic repression in AMD RPE/choroid, which may increase susceptibility to oxidative stress in AMD retinas.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-GSTM5 antibodyPathways associated with anti-GSTM5 antibody
 Reference Product  PubMed Publications
 GSTZ1 antibody  >4 publications with GSTM5 and GSTZ1
 GSTO1 antibody  >3 publications with GSTM5 and GSTO1
 GSTO2 antibody  >2 publications with GSTM5 and GSTO2
 GSTK1 antibody  >2 publications with GSTM5 and GSTK1
 GPX3 antibody  >1 publications with GSTM5 and GPX3
 MGST2 antibody  >1 publications with GSTM5 and MGST2
 MGST1 antibody  >1 publications with GSTM5 and MGST1
 GPX7 antibody  >1 publications with GSTM5 and GPX7
 Products by Pathway  Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Drug Metabolism - Cytochrome P450 Pathway antibodies  Drug Metabolism - Cytochrome P450 Pathway Diagram
 Drug Metabolism - Cytochrome P450 Pathway antibodies  Drug Metabolism - Cytochrome P450 Pathway Diagram
 Glutathione Conjugation Pathway antibodies  Glutathione Conjugation Pathway Diagram
 Glutathione Metabolism Pathway antibodies  Glutathione Metabolism Pathway Diagram
 Glutathione Metabolism Pathway antibodies  Glutathione Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Xenobiotics By Cytochrome P450 Pathway antibodies  Metabolism Of Xenobiotics By Cytochrome P450 Pathway Diagram
Diseases associated with anti-GSTM5 antibodyOrgans/Tissues associated with anti-GSTM5 antibody
 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >5 publications with GSTM5 and Adenocarcinoma
 Cardiovascular Diseases Antibodies  >3 publications with GSTM5 and Cardiovascular Diseases
 Fatty Liver Antibodies  >3 publications with GSTM5 and Fatty Liver
 Prenatal Exposure Delayed Effects Antibodies  >2 publications with GSTM5 and Prenatal Exposure Delayed Effects
 Kidney Diseases Antibodies  >2 publications with GSTM5 and Kidney Diseases
 Liver Diseases Antibodies  >2 publications with GSTM5 and Liver Diseases
 Hypertension Antibodies  >2 publications with GSTM5 and Hypertension
 Cell Transformation, Neoplastic Antibodies  >1 publications with GSTM5 and Cell Transformation, Neoplastic
 Urinary Bladder Neoplasms Antibodies  >1 publications with GSTM5 and Urinary Bladder Neoplasms
 Breast Neoplasms Antibodies  >1 publications with GSTM5 and Breast Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >7 publications with GSTM5 and Brain
 Lung Antibodies  >5 publications with GSTM5 and Lung
 Testis Antibodies  >5 publications with GSTM5 and Testis
 Heart Antibodies  >3 publications with GSTM5 and Heart
 Uterus Antibodies  >2 publications with GSTM5 and Uterus
 Muscle Antibodies  >1 publications with GSTM5 and Muscle
 Prostate Antibodies  >1 publications with GSTM5 and Prostate
 Eye Antibodies  >1 publications with GSTM5 and Eye
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