AAH36086.1
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Glycine receptor, alpha 3
NCBI Official Synonym Full Names
glycine receptor, alpha 3
NCBI Protein Information
glycine receptor subunit alpha-3; ligand gated ion channel; glycine receptor, alpha-3 polypeptide
UniProt Protein Name
Glycine receptor subunit alpha-3
UniProt Entry Name
GLRA3_HUMAN
NCBI Summary for GLRA3
This gene encodes a member of the ligand-gated ion channel protein family. The encoded protein is a member of the glycine receptor subfamily. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]
UniProt Comments for GLRA3
GLRA3: The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing). Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA3 sub- subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transporter, ion channel; Membrane protein, integral; Membrane protein, multi-pass; Transporter
Chromosomal Location of Human Ortholog: 4q34.1
Cellular Component: postsynaptic membrane; integral to plasma membrane; plasma membrane; cell junction
Molecular Function: transmitter-gated ion channel activity; extracellular-glycine-gated chloride channel activity; glycine binding
Biological Process: transmembrane transport
Research Articles on GLRA3
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Products associated with anti-GLRA3 antibody
Pathways associated with anti-GLRA3 antibody
Diseases associated with anti-GLRA3 antibody
Organs/Tissues associated with anti-GLRA3 antibody
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