NP_001007721.1
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NCBI GenBank Nucleotide #
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UniProt Related Accession #
NCBI Official Full Name
Golgi reassembly-stacking protein 2
NCBI Official Synonym Full Names
golgi reassembly stacking protein 2
NCBI Protein Information
Golgi reassembly-stacking protein 2; golgi reassembly-stacking protein of 55 kDa
UniProt Protein Name
Golgi reassembly-stacking protein 2
UniProt Synonym Protein Names
Golgi reassembly-stacking protein of 55 kDa; GRASP55
UniProt Synonym Gene Names
UniProt Entry Name
GORS2_RAT
NCBI Summary for Gorasp2
functions in the stacking of Golgi cisternae [RGD, Feb 2006]
UniProt Comments for Gorasp2
GRASP55: a golgi reassembly-stacking protein (GRASP) protein involved in the stacking of Golgi cisternae. May be involved in the process by which Golgi stacks reform after mitotic breakdown. May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as the TGF-alpha receptor. Oligomerization of its N-terminal GRASP domain regulates the formation of Golgi stacks, a process that is regulated by phosphorylation within the C-terminal Ser/Pro-rich domain. Forms a RAB2 effector complex with BLZF1 in the medial Golgi. Interacts with members of the p24 cargo receptors. Interacts with CNIH and the cytoplasmic domain of the TGF-alpha receptor, prior its transit in the trans-Golgi. Two alternatively spliced isoforms have been described.
Protein type: Motility/polarity/chemotaxis; Vesicle
Cellular Component: Golgi apparatus; plasma membrane; Golgi medial cisterna
Molecular Function: protein binding
Biological Process: organelle organization and biogenesis; Golgi organization and biogenesis
Research Articles on Gorasp2
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Organs/Tissues associated with anti-Gorasp2 antibody
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