Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow GUCY1B3 rightarrow Polyclonal GUCY1B3  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • OASIS - CREB3L1 Peptide
 • Golgi Protein 73 (GP73) ELISA Kit
 • Monocyclic monoterpene ketone monooxygenase (MMKMO) Recombinant Protein
 • MAP-2 (2a + 2b) Microtubule Associated Protein 2 (MAP2) Antibody
 • CXCL6 Antibody
 • Immunoglobulin G (IgG) ELISA Kit
 • DEFbeta2-DEFB2 ELISA Kit
 • GP IIb-IIIa Antibody
 • Versican (VCAN) ELISA Kit
 • SLC4A8 Antibody
 • L-Selectin (L-Sel) ELISA Kit
 • Norrin (Ndp) ELISA Kit
 • Mouse IgG2a Isotype Control Isotype Control
 • Antigen KI-67 (MKI67) Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-GUCY1B3 antibody :: Rabbit guanylate cyclase 1, soluble, beta 3 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS711140 anti-GUCY1B3 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

guanylate cyclase 1, soluble, beta 3 (GUCY1B3), Polyclonal Antibody

 Also Known As   

Rabbit anti-human guanylate cyclase 1, soluble, beta 3 polyclonal Antibody

 Product Synonym Names    guanylate cyclase 1; soluble; beta 3; GUCY1B3; GC-S-beta-1; GC-SB3; GUC1B3; GUCB3; GUCSB3; GUCY1B1
 Product Gene Name   

anti-GUCY1B3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    139397
Section Bar
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
Section Bar
 Purity/Purification    Antigen Affinity Purified
Section Bar
 Immunogen    Human GUCY1B3
 Storage Buffer    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-21309 / sc-21310 / sc-34431 / sc-34432 / sc-34430 / sc-20955
Section Bar
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-GUCY1B3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 Applications Tested/Suitable for anti-GUCY1B3 antibody   

ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)

Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for GUCY1B3. It may not necessarily be applicable to this product.
 NCBI GI #    37589942
 NCBI GeneID    2983
 NCBI Accession #    AAH47620.2 [Other Products]
Section Bar
 UniProt Secondary Accession #    Q86WY5; B7Z426 [Other Products]
 UniProt Related Accession #    Q02153 [Other Products]
 Molecular Weight    68,165 Da [Similar Products]
Table BarTOPTable Bar
 NCBI Official Full Name    Guanylate cyclase 1, soluble, beta 3
 NCBI Official Synonym Full Names    guanylate cyclase 1, soluble, beta 3
 NCBI Official Symbol    GUCY1B3 [Similar Products]
 NCBI Official Synonym Symbols   
GUCB3; GC-SB3; GUC1B3; GUCSB3; GUCY1B1; GC-S-beta-1
[Similar Products]
 NCBI Protein Information    guanylate cyclase soluble subunit beta-1; GCS-beta-1; GCS-beta-3; soluble guanylate cyclase small subunit; guanylate cyclase soluble subunit beta-3
 UniProt Protein Name    Guanylate cyclase soluble subunit beta-1
 UniProt Synonym Protein Names   
Guanylate cyclase soluble subunit beta-3; GCS-beta-3; Soluble guanylate cyclase small subunit
 Protein Family    Guanylate cyclase soluble
 UniProt Gene Name    GUCY1B3 [Similar Products]
 UniProt Synonym Gene Names    GUC1B3; GUCSB3; GUCY1B1; GCS-beta-1; GCS-beta-3 [Similar Products]
 UniProt Entry Name    GCYB1_HUMAN
Section Bar
 NCBI Summary for GUCY1B3    This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Section Bar
 UniProt Comments for GUCY1B3    GUCY1B3: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. Heterodimer of an alpha and a beta chain. 2 isoforms of the human protein are produced by alternative splicing

Protein type: Lyase; EC 4.6.1.2; Nucleotide Metabolism - purine; Guanylyl cyclase; Receptor, misc.

Chromosomal Location of Human Ortholog: 4q31.3-q33

Cellular Component: guanylate cyclase complex, soluble; intracellular membrane-bound organelle; cytoplasm

Molecular Function: guanylate cyclase activity; GTP binding; protein heterodimerization activity; metal ion binding; heme binding; receptor activity; Hsp90 protein binding

Biological Process: cGMP biosynthetic process; blood circulation; blood coagulation; nitric oxide mediated signal transduction
Table BarTOPTable Bar
 Research Articles on GUCY1B3    1. Dynamic interplay between hsp90, apo-sGC-beta1, and sGC-alpha1 in response to NO is unprecedented and represent new steps by which cells can modulate the heme content and activity of sGC for signaling cascades.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-GUCY1B3 antibodyPathways associated with anti-GUCY1B3 antibody
 Reference Product  PubMed Publications
 GUCY1A3 antibody  >5 publications with GUCY1B3 and GUCY1A3
 Products by Pathway  Pathway Diagram
 Circadian Entrainment Pathway antibodies  Circadian Entrainment Pathway Diagram
 Circadian Entrainment Pathway antibodies  Circadian Entrainment Pathway Diagram
 Gap Junction Pathway antibodies  Gap Junction Pathway Diagram
 Gap Junction Pathway antibodies  Gap Junction Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Long-term Depression Pathway antibodies  Long-term Depression Pathway Diagram
 Long-term Depression Pathway antibodies  Long-term Depression Pathway Diagram
 Nitric Oxide Stimulates Guanylate Cyclase Pathway antibodies  Nitric Oxide Stimulates Guanylate Cyclase Pathway Diagram
 Oxytocin Signaling Pathway antibodies  Oxytocin Signaling Pathway Diagram
 Oxytocin Signaling Pathway antibodies  Oxytocin Signaling Pathway Diagram
Diseases associated with anti-GUCY1B3 antibodyOrgans/Tissues associated with anti-GUCY1B3 antibody
 Disease Name  Pubmed Publications
 Heart Diseases Antibodies  >1 publications with GUCY1B3 and Heart Diseases
 Nervous System Diseases Antibodies  >1 publications with GUCY1B3 and Nervous System Diseases
 Brain Diseases Antibodies  >1 publications with GUCY1B3 and Brain Diseases
 Hypertension Antibodies  >1 publications with GUCY1B3 and Hypertension
 Cardiovascular Diseases Antibodies  >1 publications with GUCY1B3 and Cardiovascular Diseases
 Kidney Diseases Antibodies  >1 publications with GUCY1B3 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >6 publications with GUCY1B3 and Vascular
 Embryonic Tissue Antibodies  >3 publications with GUCY1B3 and Embryonic Tissue
 Muscle Antibodies  >2 publications with GUCY1B3 and Muscle
 Heart Antibodies  >2 publications with GUCY1B3 and Heart
 Ovary Antibodies  >2 publications with GUCY1B3 and Ovary
 Placenta Antibodies  >2 publications with GUCY1B3 and Placenta
 Brain Antibodies  >2 publications with GUCY1B3 and Brain
 Stomach Antibodies  >1 publications with GUCY1B3 and Stomach
 Uterus Antibodies  >1 publications with GUCY1B3 and Uterus
 Kidney Antibodies  >1 publications with GUCY1B3 and Kidney
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions