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anti-HSD17B7 antibody :: Rabbit hydroxysteroid (17-beta) dehydrogenase 7 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS714476 anti-HSD17B7 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

hydroxysteroid (17-beta) dehydrogenase 7 (HSD17B7), Polyclonal Antibody

 Also Known As   

Rabbit anti-human hydroxysteroid (17-beta) dehydrogenase 7 polyclonal Antibody

 Product Synonym Names    hydroxysteroid (17-beta) dehydrogenase 7 pseudogene 2; HSD17B7P2; FLJ40773; HSD17B7; Hsd17b_2; MGC88684; bA291L22.1
 Product Gene Name   

anti-HSD17B7 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    606756
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human HSD17B7P2
 Storage Buffer    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-160117
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-HSD17B7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-HSD17B7 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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NCBI/Uniprot data below describe general gene information for HSD17B7. It may not necessarily be applicable to this product.
 NCBI GI #    40807207
 NCBI GeneID    51478
 NCBI Accession #    AAH65246.1 [Other Products]
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 UniProt Secondary Accession #    Q5T246; Q7Z4V9; Q8WWS2; Q9UF00 [Other Products]
 UniProt Related Accession #    P56937 [Other Products]
 Molecular Weight    34,476 Da [Similar Products]
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 NCBI Official Full Name    Hydroxysteroid (17-beta) dehydrogenase 7
 NCBI Official Synonym Full Names    hydroxysteroid (17-beta) dehydrogenase 7
 NCBI Official Symbol    HSD17B7 [Similar Products]
 NCBI Official Synonym Symbols   
PRAP; SDR37C1
[Similar Products]
 NCBI Protein Information    3-keto-steroid reductase; 17-beta-HSD 7; estradiol 17-beta-dehydrogenase 7; 17beta hydroxysteroid dehydrogenase; 17-beta-hydroxysteroid dehydrogenase 7; 17 beta-hydroxysteroid dehydrogenase type VII; short chain dehydrogenase/reductase family 37C, member 1
 UniProt Protein Name    3-keto-steroid reductase
 UniProt Synonym Protein Names   
17-beta-hydroxysteroid dehydrogenase 7; 17-beta-HSD 7; Estradiol 17-beta-dehydrogenase 7 (EC:1.1.1.62)
 UniProt Gene Name    HSD17B7 [Similar Products]
 UniProt Synonym Gene Names    17-beta-HSD 7 [Similar Products]
 UniProt Entry Name    DHB7_HUMAN
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 NCBI Summary for HSD17B7    HSD17B7 encodes an enzyme that functions both as a 17-beta-hydroxysteroid dehydrogenase (EC 1.1.1.62) in the biosynthesis of sex steroids and as a 3-ketosteroid reductase (EC 1.1.1.270) in the biosynthesis of cholesterol (Marijanovic et al., 2003 [PubMed 12829805]).[supplied by OMIM, May 2010]
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 UniProt Comments for HSD17B7    HSD17B7: Responsible for the reduction of the keto group on the C-3 of sterols. Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Oxidoreductase; EC 1.1.1.62; Membrane protein, integral; Lipid Metabolism - androgen and estrogen; Lipid Metabolism - steroid biosynthesis; Endoplasmic reticulum; EC 1.1.1.270

Chromosomal Location of Human Ortholog: 1q23

Cellular Component: endoplasmic reticulum membrane; plasma membrane; integral to membrane

Molecular Function: estradiol 17-beta-dehydrogenase activity; prolactin receptor binding; 3-keto sterol reductase activity

Biological Process: estrogen biosynthetic process; cholesterol biosynthetic process
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 Research Articles on HSD17B7    1. The transcriptional activity of the HSD17B7 gene containing the G allele is higher than that of the C allele. This difference in HSD17B7 expression may regulate the risk of peripheral edema as an adverse reaction induced by estramustine phosphate sodium
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-HSD17B7 antibodyPathways associated with anti-HSD17B7 antibody
 Reference Product  PubMed Publications
 HSD17B1 antibody  >6 publications with HSD17B7 and HSD17B1
 NSDHL antibody  >2 publications with HSD17B7 and NSDHL
 LSS antibody  >2 publications with HSD17B7 and LSS
 SQLE antibody  >2 publications with HSD17B7 and SQLE
 FDFT1 antibody  >1 publications with HSD17B7 and FDFT1
 SC4MOL antibody  >1 publications with HSD17B7 and SC4MOL
 Products by Pathway  Pathway Diagram
 Cholesterol Biosynthesis Pathway antibodies  Cholesterol Biosynthesis Pathway Diagram
 Cholesterol Biosynthesis, Squalene 2,3-epoxide => Cholesterol Pathway antibodies  Cholesterol Biosynthesis, Squalene 2,3-epoxide => Cholesterol Pathway Diagram
 Cholesterol Biosynthesis, Squalene 2,3-epoxide => Cholesterol Pathway antibodies  Cholesterol Biosynthesis, Squalene 2,3-epoxide => Cholesterol Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Ovarian Steroidogenesis Pathway antibodies  Ovarian Steroidogenesis Pathway Diagram
 Ovarian Steroidogenesis Pathway antibodies  Ovarian Steroidogenesis Pathway Diagram
 Prostate Cancer Pathway antibodies  Prostate Cancer Pathway Diagram
 Steroid Biosynthesis Pathway antibodies  Steroid Biosynthesis Pathway Diagram
Diseases associated with anti-HSD17B7 antibodyOrgans/Tissues associated with anti-HSD17B7 antibody
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >5 publications with HSD17B7 and Breast Neoplasms
 Adenocarcinoma Antibodies  >3 publications with HSD17B7 and Adenocarcinoma
 Carcinoma, Hepatocellular Antibodies  >2 publications with HSD17B7 and Carcinoma, Hepatocellular
 Neoplasms, Experimental Antibodies  >2 publications with HSD17B7 and Neoplasms, Experimental
 Liver Neoplasms Antibodies  >2 publications with HSD17B7 and Liver Neoplasms
 Liver Diseases Antibodies  >2 publications with HSD17B7 and Liver Diseases
 Ovarian Diseases Antibodies  >1 publications with HSD17B7 and Ovarian Diseases
 Hypertrophy Antibodies  >1 publications with HSD17B7 and Hypertrophy
 Edema Antibodies  >1 publications with HSD17B7 and Edema
 Mammary Neoplasms, Animal Antibodies  >1 publications with HSD17B7 and Mammary Neoplasms, Animal
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >8 publications with HSD17B7 and Liver
 Ovary Antibodies  >7 publications with HSD17B7 and Ovary
 Blood Antibodies  >5 publications with HSD17B7 and Blood
 Brain Antibodies  >4 publications with HSD17B7 and Brain
 Mammary Gland Antibodies  >3 publications with HSD17B7 and Mammary Gland
 Embryonic Tissue Antibodies  >3 publications with HSD17B7 and Embryonic Tissue
 Heart Antibodies  >3 publications with HSD17B7 and Heart
 Testis Antibodies  >2 publications with HSD17B7 and Testis
 Muscle Antibodies  >2 publications with HSD17B7 and Muscle
 Placenta Antibodies  >2 publications with HSD17B7 and Placenta
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