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anti-ITGB6 antibody :: Rabbit anti-Human integrin, beta 6 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS712187 anti-ITGB6 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

integrin, beta 6 (ITGB6), Polyclonal Antibody

 Also Known As   

Rabbit anti-human integrin, beta 6 polyclonal Antibody

 Product Synonym Names    integrin; beta 6;
 Product Gene Name   

anti-ITGB6 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    147558
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human ITGB6-Specific
 Storage Buffer    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-6633 / sc-6632 / sc-15329
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-ITGB6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-ITGB6 antibody   

ELISA (EIA), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for ITGB6. It may not necessarily be applicable to this product.
 NCBI GI #    111306467
 NCBI GeneID    3694
 NCBI Accession #    AAI21179.1 [Other Products]
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 UniProt Secondary Accession #    Q0VA95; Q16500; Q53RG5; Q53RR6; B2R9W5; C9JA97 [Other Products]
 UniProt Related Accession #    P18564 [Other Products]
 Molecular Weight    74,958 Da [Similar Products]
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 NCBI Official Full Name    Integrin, beta 6
 NCBI Official Synonym Full Names    integrin, beta 6
 NCBI Official Symbol    ITGB6 [Similar Products]
 NCBI Protein Information    integrin beta-6
 UniProt Protein Name    Integrin beta-6
 Protein Family    Integrin
 UniProt Gene Name    ITGB6 [Similar Products]
 UniProt Entry Name    ITB6_HUMAN
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 NCBI Summary for ITGB6    This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms a dimer with an alpha v chain and this heterodimer can bind to ligands like fibronectin and transforming growth factor beta 1. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
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 UniProt Comments for ITGB6    ITGB6: Integrin alpha-V/beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. Belongs to the integrin beta chain family.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Cell adhesion

Chromosomal Location of Human Ortholog: 2q24.2

Cellular Component: plasma membrane; integrin complex; receptor complex; external side of plasma membrane

Molecular Function: integrin binding; viral receptor activity

Biological Process: integrin-mediated signaling pathway; extracellular matrix organization and biogenesis; entry of virus into host cell; multicellular organismal development; cell-matrix adhesion; inflammatory response; cell adhesion

Disease: Amelogenesis Imperfecta, Type Ih
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 Research Articles on ITGB6    1. upregulation of alphavbeta6 on myoepithelial cells generates a tumor promoter function through TGFbeta upregulation of MMP-9. These data suggest that expression of alphavbeta6 may be used to stratify patients with DCIS.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ITGB6 antibodyPathways associated with anti-ITGB6 antibody
 Reference Product  PubMed Publications
 ITGAV antibody  >5 publications with ITGB6 and ITGAV
 FBN1 antibody  >1 publications with ITGB6 and FBN1
 Products by Pathway  Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
 Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies  Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
 Dilated Cardiomyopathy Pathway antibodies  Dilated Cardiomyopathy Pathway Diagram
 Dilated Cardiomyopathy Pathway antibodies  Dilated Cardiomyopathy Pathway Diagram
 ECM Proteoglycans Pathway antibodies  ECM Proteoglycans Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 Elastic Fibre Formation Pathway antibodies  Elastic Fibre Formation Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
Diseases associated with anti-ITGB6 antibodyOrgans/Tissues associated with anti-ITGB6 antibody
 Disease Name  Pubmed Publications
 Lung Diseases Antibodies  >9 publications with ITGB6 and Lung Diseases
 Inflammation Antibodies  >5 publications with ITGB6 and Inflammation
 Fibrosis Antibodies  >5 publications with ITGB6 and Fibrosis
 Disease Models, Animal Antibodies  >4 publications with ITGB6 and Disease Models, Animal
 Pulmonary Emphysema Antibodies  >4 publications with ITGB6 and Pulmonary Emphysema
 Congenital Abnormalities Antibodies  >3 publications with ITGB6 and Congenital Abnormalities
 Nervous System Diseases Antibodies  >2 publications with ITGB6 and Nervous System Diseases
 Kidney Diseases Antibodies  >1 publications with ITGB6 and Kidney Diseases
 Breast Neoplasms Antibodies  >1 publications with ITGB6 and Breast Neoplasms
 Carcinoma, Hepatocellular Antibodies  >1 publications with ITGB6 and Carcinoma, Hepatocellular
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >9 publications with ITGB6 and Lung
 Mouth Antibodies  >4 publications with ITGB6 and Mouth
 Brain Antibodies  >4 publications with ITGB6 and Brain
 Skin Antibodies  >3 publications with ITGB6 and Skin
 Kidney Antibodies  >2 publications with ITGB6 and Kidney
 Nerve Antibodies  >1 publications with ITGB6 and Nerve
 Heart Antibodies  >1 publications with ITGB6 and Heart
 Prostate Antibodies  >1 publications with ITGB6 and Prostate
 Placenta Antibodies  >1 publications with ITGB6 and Placenta
 Uterus Antibodies  >1 publications with ITGB6 and Uterus
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