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anti-IFITM3 antibody :: Rabbit interferon induced transmembrane protein 3 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS714813 anti-IFITM3 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

interferon induced transmembrane protein 3 (IFITM3), Polyclonal Antibody

 Also Known As   

Rabbit anti-human interferon induced transmembrane protein 3 (1-8U) polyclonal Antibody

 Product Synonym Names    interferon induced transmembrane protein 3 (1-8U); IFITM3; 1-8U; IP15
 Product Gene Name   

anti-IFITM3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    gene 614680
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human IFITM3
 Storage Buffer    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-130785
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-IFITM3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-IFITM3 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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NCBI/Uniprot data below describe general gene information for IFITM3. It may not necessarily be applicable to this product.
 NCBI GI #    148612842
 NCBI GeneID    10410
 NCBI Accession #    NP_066362.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_021034.2 [Other Products]
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 UniProt Secondary Accession #    Q53Y76; Q96HK8; Q96J15 [Other Products]
 UniProt Related Accession #    Q01628 [Other Products]
 Molecular Weight    14,632 Da [Similar Products]
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 NCBI Official Full Name    interferon-induced transmembrane protein 3
 NCBI Official Synonym Full Names    interferon induced transmembrane protein 3
 NCBI Official Symbol    IFITM3 [Similar Products]
 NCBI Official Synonym Symbols   
1-8U; IP15; DSPA2b
[Similar Products]
 NCBI Protein Information    interferon-induced transmembrane protein 3; dispanin subfamily A member 2b; interferon-inducible protein 1-8U
 UniProt Protein Name    Interferon-induced transmembrane protein 3
 UniProt Synonym Protein Names   
Dispanin subfamily A member 2b; DSPA2b; Interferon-inducible protein 1-8U
 Protein Family    Interferon-induced transmembrane protein
 UniProt Gene Name    IFITM3 [Similar Products]
 UniProt Synonym Gene Names    DSPA2b [Similar Products]
 UniProt Entry Name    IFM3_HUMAN
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 NCBI Summary for IFITM3    The protein encoded by this gene is an interferon-induced membrane protein that helps confer immunity to influenza A H1N1 virus, West Nile virus, and dengue virus. Two transcript variants, only one of them protein-coding, have been found for this gene. Another variant encoding an N-terminally truncated isoform has been reported, but the full-length nature of this variant has not been determined. [provided by RefSeq, May 2012]
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 UniProt Comments for IFITM3    IFITM3: IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus (WNV), and dengue virus (WNV), by inhibiting the early step(s) of replication. Interacts with SPP1; the interaction reduces OPN expression. By IFN-alpha and IFNG/IFN-gamma. Belongs to the CD225/Dispanin family.

Protein type: Cell surface; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: lysosomal membrane; late endosome membrane; integral to membrane; plasma membrane

Molecular Function: protein binding

Biological Process: negative regulation of viral transcription; negative regulation of viral genome replication; negative regulation of virion penetration into host cell; cytokine and chemokine mediated signaling pathway; response to virus; immune response; defense response to virus

Disease: Influenza, Severe, Susceptibility To
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 Research Articles on IFITM3    1. Authors found evidence of an association between rs12252 rare allele homozygotes and susceptibility to mild influenza (in patients attending primary care).
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-IFITM3 antibodyPathways associated with anti-IFITM3 antibody
 Reference Product  PubMed Publications
 IFITM1 antibody  >28 publications with IFITM3 and IFITM1
 IFITM2 antibody  >25 publications with IFITM3 and IFITM2
 IFNA17 antibody  >14 publications with IFITM3 and IFNA17
 NAMPT antibody  >1 publications with IFITM3 and NAMPT
 SPP1 antibody  >1 publications with IFITM3 and SPP1
 Products by Pathway  Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Interferon Signaling Pathway antibodies  Interferon Signaling Pathway Diagram
 Interferon Alpha/beta Signaling Pathway antibodies  Interferon Alpha/beta Signaling Pathway Diagram
Diseases associated with anti-IFITM3 antibodyOrgans/Tissues associated with anti-IFITM3 antibody
 Disease Name  Pubmed Publications
 Influenza, Human Antibodies  >25 publications with IFITM3 and Influenza, Human
 Carcinoma Antibodies  >8 publications with IFITM3 and Carcinoma
 Inflammation Antibodies  >7 publications with IFITM3 and Inflammation
 Brain Diseases Antibodies  >4 publications with IFITM3 and Brain Diseases
 Lung Diseases Antibodies  >4 publications with IFITM3 and Lung Diseases
 Nervous System Diseases Antibodies  >4 publications with IFITM3 and Nervous System Diseases
 Adenocarcinoma Antibodies  >4 publications with IFITM3 and Adenocarcinoma
 Neoplasms, Experimental Antibodies  >3 publications with IFITM3 and Neoplasms, Experimental
 Disease Models, Animal Antibodies  >3 publications with IFITM3 and Disease Models, Animal
 Necrosis Antibodies  >3 publications with IFITM3 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >10 publications with IFITM3 and Lung
 Blood Antibodies  >10 publications with IFITM3 and Blood
 Brain Antibodies  >10 publications with IFITM3 and Brain
 Embryonic Tissue Antibodies  >5 publications with IFITM3 and Embryonic Tissue
 Heart Antibodies  >4 publications with IFITM3 and Heart
 Intestine Antibodies  >4 publications with IFITM3 and Intestine
 Bone Antibodies  >4 publications with IFITM3 and Bone
 Liver Antibodies  >3 publications with IFITM3 and Liver
 Vascular Antibodies  >3 publications with IFITM3 and Vascular
 Uterus Antibodies  >3 publications with IFITM3 and Uterus
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