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anti-IL1RL1 antibody :: Rabbit interleukin 1 receptor-like 1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS714523 anti-IL1RL1 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

interleukin 1 receptor-like 1 (IL1RL1), Polyclonal Antibody

 Also Known As   

Rabbit anti-human interleukin 1 receptor-like 1 polyclonal Antibody

 Product Synonym Names    interleukin 1 receptor-like 1; IL1RL1; DER4; FIT-1; MGC32623; ST2; ST2L; ST2V; T1
 Product Gene Name   

anti-IL1RL1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    601203
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human IL1RL1
 Storage Buffer    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-18687
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-IL1RL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-IL1RL1 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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NCBI/Uniprot data below describe general gene information for IL1RL1. It may not necessarily be applicable to this product.
 NCBI GI #    27894324
 NCBI GeneID    9173
 NCBI Accession #    NP_057316.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_016232.4 [Other Products]
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 UniProt Secondary Accession #    Q53TU7; Q8NEJ3; Q9ULV7; Q9UQ44; A8K6B3; B4E0I3 [Other Products]
 UniProt Related Accession #    Q01638 [Other Products]
 Molecular Weight    23,723 Da [Similar Products]
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 NCBI Official Full Name    interleukin-1 receptor-like 1 isoform 1
 NCBI Official Synonym Full Names    interleukin 1 receptor-like 1
 NCBI Official Symbol    IL1RL1 [Similar Products]
 NCBI Official Synonym Symbols   
T1; ST2; DER4; ST2L; ST2V; FIT-1; IL33R
[Similar Products]
 NCBI Protein Information    interleukin-1 receptor-like 1; growth stimulation-expressed; interleukin 1 receptor-related protein; homolog of mouse growth stimulation-expressed
 UniProt Protein Name    Interleukin-1 receptor-like 1
 UniProt Synonym Protein Names   
Protein ST2
 Protein Family    Interleukin-1 receptor
 UniProt Gene Name    IL1RL1 [Similar Products]
 UniProt Synonym Gene Names    DER4; ST2; T1 [Similar Products]
 UniProt Entry Name    ILRL1_HUMAN
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 NCBI Summary for IL1RL1    The protein encoded by this gene is a member of the interleukin 1 receptor family. Studies of the similar gene in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) and interleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
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 UniProt Comments for IL1RL1    IL1RL1: receptor for IL33. Its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of ERK1 and/or ERK2, p38-alpha, and JNK1. Apparently promotes the activation and differentiation of T-helper 2 cells. Belongs to the interleukin-1 receptor family. Highly expressed in kidney, lung, placenta, stomach, skeletal muscle, colon and small intestine. Three isoforms of the human protein are produced by alternative splicing. Isoform A is prevalently expressed in the lung, testis, placenta, stomach and colon. Isoform B is more abundant in the brain, kidney and the liver. Isoform C is not detected in brain, heart, liver, kidney and skeletal muscle.

Protein type: Receptor, cytokine; Membrane protein, integral

Chromosomal Location of Human Ortholog: 2q12

Cellular Component: extracellular matrix; integral to membrane; extracellular region; external side of plasma membrane

Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; protein binding; receptor signaling protein activity; interleukin-1 receptor activity

Biological Process: negative regulation of T-helper 1 type immune response; negative regulation of interferon-gamma production; immune response; negative regulation of I-kappaB kinase/NF-kappaB cascade; signal transduction; positive regulation of interleukin-5 production; positive regulation of macrophage activation; positive regulation of inflammatory response
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 Research Articles on IL1RL1    1. IL-33/ST2 and traditional cytokines were involved in decline of cardiac function of end stage heart failure patients as well as in hemodynamic recovery induced by LVAD.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-IL1RL1 antibodyDiseases associated with anti-IL1RL1 antibody
 Reference Product  PubMed Publications
 IL33 antibody  >147 publications with IL1RL1 and IL33
 MYD88 antibody  >18 publications with IL1RL1 and MYD88
 IL1RAP antibody  >9 publications with IL1RL1 and IL1RAP
 ORMDL3 antibody  >8 publications with IL1RL1 and ORMDL3
 TIRAP antibody  >3 publications with IL1RL1 and TIRAP
 TRAF6 antibody  >3 publications with IL1RL1 and TRAF6
 IRAK4 antibody  >2 publications with IL1RL1 and IRAK4
 NCF1 antibody  >1 publications with IL1RL1 and NCF1
 TMED1 antibody  >1 publications with IL1RL1 and TMED1
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >164 publications with IL1RL1 and Inflammation
 Cardiovascular Diseases Antibodies  >114 publications with IL1RL1 and Cardiovascular Diseases
 Heart Diseases Antibodies  >99 publications with IL1RL1 and Heart Diseases
 Lung Diseases Antibodies  >89 publications with IL1RL1 and Lung Diseases
 Asthma Antibodies  >80 publications with IL1RL1 and Asthma
 Necrosis Antibodies  >44 publications with IL1RL1 and Necrosis
 Disease Models, Animal Antibodies  >40 publications with IL1RL1 and Disease Models, Animal
 Fibrosis Antibodies  >20 publications with IL1RL1 and Fibrosis
 Pneumonia Antibodies  >14 publications with IL1RL1 and Pneumonia
 Hypertension Antibodies  >12 publications with IL1RL1 and Hypertension
Organs/Tissues associated with anti-IL1RL1 antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >293 publications with IL1RL1 and Blood
 Heart Antibodies  >117 publications with IL1RL1 and Heart
 Lung Antibodies  >68 publications with IL1RL1 and Lung
 Brain Antibodies  >46 publications with IL1RL1 and Brain
 Vascular Antibodies  >27 publications with IL1RL1 and Vascular
 Liver Antibodies  >20 publications with IL1RL1 and Liver
 Kidney Antibodies  >8 publications with IL1RL1 and Kidney
 Placenta Antibodies  >6 publications with IL1RL1 and Placenta
 Thymus Antibodies  >3 publications with IL1RL1 and Thymus
 Nerve Antibodies  >3 publications with IL1RL1 and Nerve
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