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anti-IL17RB antibody :: Rabbit anti-Human interleukin 17 receptor B Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS714260 anti-IL17RB antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

interleukin 17 receptor B (IL17RB), Polyclonal Antibody

 Also Known As   

Rabbit anti-human interleukin 17 receptor B polyclonal Antibody

 Product Synonym Names    interleukin 17 receptor B; IL17RB; CRL4; EVI27; IL17BR; IL17RH1; MGC5245
 Product Gene Name   

anti-IL17RB antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    605458
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human IL17RB
 Storage Buffer    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-11754
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-IL17RB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-IL17RB antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

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NCBI/Uniprot data below describe general gene information for IL17RB. It may not necessarily be applicable to this product.
 NCBI GI #    27477074
 NCBI GeneID    55540
 NCBI Accession #    NP_061195.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_018725.3 [Other Products]
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 UniProt Secondary Accession #    Q9BPZ0; Q9NRL4; Q9NRM5 [Other Products]
 UniProt Related Accession #    Q9NRM6 [Other Products]
 Molecular Weight    31,773 Da [Similar Products]
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 NCBI Official Full Name    interleukin-17 receptor B
 NCBI Official Synonym Full Names    interleukin 17 receptor B
 NCBI Official Symbol    IL17RB [Similar Products]
 NCBI Official Synonym Symbols   
CRL4; EVI27; IL17BR; IL17RH1
[Similar Products]
 NCBI Protein Information    interleukin-17 receptor B; IL-17RB; IL-17Rh1; IL-17B receptor; IL-17 receptor B; cytokine receptor CRL4; IL-17 receptor homolog 1; cytokine receptor-like 4; interleukin 17B receptor; interleukin-17B receptor; interleukin 17 receptor homolog 1
 UniProt Protein Name    Interleukin-17 receptor B
 UniProt Synonym Protein Names   
Cytokine receptor-like 4; IL-17 receptor homolog 1; IL-17Rh1; IL17Rh1; Interleukin-17B receptor; IL-17B receptor
 Protein Family    Interleukin-17 receptor
 UniProt Gene Name    IL17RB [Similar Products]
 UniProt Synonym Gene Names    CRL4; EVI27; IL17BR; IL-17 receptor B; IL-17RB; IL-17Rh1; IL17Rh1; IL-17B receptor [Similar Products]
 UniProt Entry Name    I17RB_HUMAN
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 NCBI Summary for IL17RB    The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. [provided by RefSeq, Jul 2008]
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 UniProt Comments for IL17RB    IL17RB: Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 3p21.1

Cellular Component: cell surface; membrane; integral to plasma membrane; cytoplasm; extracellular region

Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; interleukin-17 receptor activity

Biological Process: cytokine and chemokine mediated signaling pathway; defense response; regulation of cell growth
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 Research Articles on IL17RB    1. Results show that amplified signaling of interleukin-17 receptor B (IL-17RB) and its ligand IL-17B promot tumorigenicity in breast cancer cells and impeded acinus formation in immortalized normal mammary epithelial cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-IL17RB antibodyPathways associated with anti-IL17RB antibody
 Reference Product  PubMed Publications
 IL17A antibody  >19 publications with IL17RB and IL17A
 IL17C antibody  >19 publications with IL17RB and IL17C
 IL25 antibody  >3 publications with IL17RB and IL25
 CHDH antibody  >2 publications with IL17RB and CHDH
 DAZAP2 antibody  >1 publications with IL17RB and DAZAP2
 IL17RE antibody  >1 publications with IL17RB and IL17RE
 TRAF6 antibody  >1 publications with IL17RB and TRAF6
 IL17RC antibody  >1 publications with IL17RB and IL17RC
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 IL17 Signaling Pathway antibodies  IL17 Signaling Pathway Diagram
Diseases associated with anti-IL17RB antibodyOrgans/Tissues associated with anti-IL17RB antibody
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >17 publications with IL17RB and Breast Neoplasms
 Inflammation Antibodies  >15 publications with IL17RB and Inflammation
 Neoplasms, Experimental Antibodies  >6 publications with IL17RB and Neoplasms, Experimental
 Necrosis Antibodies  >3 publications with IL17RB and Necrosis
 Nervous System Diseases Antibodies  >1 publications with IL17RB and Nervous System Diseases
 Renal Insufficiency Antibodies  >1 publications with IL17RB and Renal Insufficiency
 Congenital Abnormalities Antibodies  >1 publications with IL17RB and Congenital Abnormalities
 Fibrosis Antibodies  >1 publications with IL17RB and Fibrosis
 Neoplasm Metastasis Antibodies  >1 publications with IL17RB and Neoplasm Metastasis
 Kidney Diseases Antibodies  >1 publications with IL17RB and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >9 publications with IL17RB and Lung
 Lymph Node Antibodies  >3 publications with IL17RB and Lymph Node
 Kidney Antibodies  >2 publications with IL17RB and Kidney
 Testis Antibodies  >1 publications with IL17RB and Testis
 Heart Antibodies  >1 publications with IL17RB and Heart
 Muscle Antibodies  >1 publications with IL17RB and Muscle
 Liver Antibodies  >1 publications with IL17RB and Liver
 Placenta Antibodies  >1 publications with IL17RB and Placenta
 Uterus Antibodies  >1 publications with IL17RB and Uterus
 Brain Antibodies  >1 publications with IL17RB and Brain
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