Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow IL18 rightarrow Polyclonal IL18  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • OLFM4 - Olfactomedin 4 Antibody
 • C3 Antibody
 • HPSE cDNA Clone
 • a1-Acid Glycoprotein (Orm1) Antibody
 • RAC-alpha serine-threonine-protein kinase Antibody
 • Acetylcholinesterase (ACHE) ELISA Kit
 • HSP90 alpha Recombinant Protein
 • Interleukin-17 A-F (rIL 17 A-F) Recombinant Protein
 • ADAM metallopeptidase domain 29 (ADAM29) ELISA Kit
 • Casein Kinase 2, beta (CSNK2B) ELISA Kit
 • CD34 Antibody
 • Interferon alpha-beta receptor 2 (Ifnar2) ELISA Kit
 • SEMA3A ELISA Kit
 • dickkopf homolog 4 (Xenopus laevis) (DKK4) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-IL18 antibody :: Rabbit anti-Human interleukin 18 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS710140 anti-IL18 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

interleukin 18 (IL18), Polyclonal Antibody

 Also Known As   

Rabbit anti-human interleukin 18 (interferon-gamma-inducing factor) polyclonal Antibody

 Product Synonym Names    interleukin 18 (interferon-gamma-inducing factor); IL18; IGIF; IL-18; IL-1g; IL1F4; MGC12320
 Product Gene Name   

anti-IL18 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    600953
Section Bar
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
Section Bar
 Purity/Purification    Antigen Affinity Purified
Section Bar
 Immunogen    Human Pre-IL18
 Storage Buffer    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-7954
Section Bar
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-IL18 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 Applications Tested/Suitable for anti-IL18 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for IL18. It may not necessarily be applicable to this product.
 NCBI GI #    4504653
 NCBI GeneID    3606
 NCBI Accession #    NP_001553.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001562.3 [Other Products]
Section Bar
 UniProt Secondary Accession #    O75599; Q6FGY3; Q6WWJ7 [Other Products]
 UniProt Related Accession #    Q14116 [Other Products]
 Molecular Weight    21,896 Da [Similar Products]
Table BarTOPTable Bar
 NCBI Official Full Name    interleukin-18 isoform 1 proprotein
 NCBI Official Synonym Full Names    interleukin 18
 NCBI Official Symbol    IL18 [Similar Products]
 NCBI Official Synonym Symbols   
IGIF; IL-18; IL-1g; IL1F4
[Similar Products]
 NCBI Protein Information    interleukin-18; IL-1 gamma; iboctadekin; interleukin-1 gamma; IFN-gamma-inducing factor; interleukin 18 (interferon-gamma-inducing factor)
 UniProt Protein Name    Interleukin-18
 UniProt Synonym Protein Names   
Iboctadekin; Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; IL-1 gamma
 Protein Family    Interleukin
 UniProt Gene Name    IL18 [Similar Products]
 UniProt Synonym Gene Names    IGIF; IL1F4; IL-18; IFN-gamma-inducing factor; IL-1 gamma [Similar Products]
 UniProt Entry Name    IL18_HUMAN
Section Bar
 NCBI Summary for IL18    The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity in spleen cells, and stimulates interferon gamma production in T-helper type I cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011]
Section Bar
 UniProt Comments for IL18    IL18: Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells. Belongs to the IL-1 family.

Protein type: Cytokine

Chromosomal Location of Human Ortholog: 11q22.2-q22.3

Cellular Component: extracellular space; extracellular region; cytosol

Molecular Function: protein binding; cytokine activity

Biological Process: positive regulation of granulocyte macrophage colony-stimulating factor production; positive regulation of NK T cell proliferation; natural killer cell activation; positive regulation of NF-kappaB import into nucleus; positive regulation of activated T cell proliferation; chemokine biosynthetic process; cell-cell signaling; lipopolysaccharide-mediated signaling pathway; granulocyte macrophage colony-stimulating factor biosynthetic process; angiogenesis; inflammatory response; regulation of cell adhesion; positive regulation of interleukin-17 production; T-helper 1 type immune response; positive regulation of natural killer cell proliferation; interleukin-2 biosynthetic process; T-helper 2 type immune response; MAPKKK cascade; interleukin-13 biosynthetic process; sleep; positive regulation of interferon-gamma production; positive regulation of tissue remodeling; interferon-gamma biosynthetic process; immune response; negative regulation of myoblast differentiation; positive regulation of inflammatory response
Table BarTOPTable Bar
 Research Articles on IL18    1. THP-1 monocyte-secreted IL-1beta/IL-18 promotes vascular smooth muscle cell proliferation.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-IL18 antibodyPathways associated with anti-IL18 antibody
 Reference Product  PubMed Publications
 CASP1 antibody  >520 publications with IL18 and CASP1
 IL10 antibody  >297 publications with IL18 and IL10
 IL18R1 antibody  >220 publications with IL18 and IL18R1
 IL13 antibody  >90 publications with IL18 and IL13
 IL6 antibody  >72 publications with IL18 and IL6
 IL18RAP antibody  >35 publications with IL18 and IL18RAP
 IL1B antibody  >30 publications with IL18 and IL1B
 IFNG antibody  >23 publications with IL18 and IFNG
 IL18BP antibody  >19 publications with IL18 and IL18BP
 CCR5 antibody  >18 publications with IL18 and CCR5
 Products by Pathway  Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 Cellular Roles Of Anthrax Toxin Pathway antibodies  Cellular Roles Of Anthrax Toxin Pathway Diagram
 Corticotropin-releasing Hormone Pathway antibodies  Corticotropin-releasing Hormone Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Hypertrophy Model Pathway antibodies  Hypertrophy Model Pathway Diagram
Diseases associated with anti-IL18 antibodyOrgans/Tissues associated with anti-IL18 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1203 publications with IL18 and Inflammation
 Necrosis Antibodies  >798 publications with IL18 and Necrosis
 Cardiovascular Diseases Antibodies  >434 publications with IL18 and Cardiovascular Diseases
 Lung Diseases Antibodies  >328 publications with IL18 and Lung Diseases
 Kidney Diseases Antibodies  >307 publications with IL18 and Kidney Diseases
 Hypersensitivity Antibodies  >266 publications with IL18 and Hypersensitivity
 Liver Diseases Antibodies  >238 publications with IL18 and Liver Diseases
 Arthritis, Rheumatoid Antibodies  >221 publications with IL18 and Arthritis, Rheumatoid
 Heart Diseases Antibodies  >204 publications with IL18 and Heart Diseases
 Hypersensitivity, Immediate Antibodies  >188 publications with IL18 and Hypersensitivity, Immediate
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >406 publications with IL18 and Liver
 Lung Antibodies  >316 publications with IL18 and Lung
 Heart Antibodies  >217 publications with IL18 and Heart
 Bone Antibodies  >215 publications with IL18 and Bone
 Brain Antibodies  >212 publications with IL18 and Brain
 Skin Antibodies  >212 publications with IL18 and Skin
 Intestine Antibodies  >157 publications with IL18 and Intestine
 Bone Marrow Antibodies  >144 publications with IL18 and Bone Marrow
 Muscle Antibodies  >133 publications with IL18 and Muscle
 Connective Tissue Antibodies  >74 publications with IL18 and Connective Tissue
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions