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| Product Name
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interleukin 18 (IL18), Polyclonal Antibody
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| Also Known As
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Rabbit anti-human interleukin 18 (interferon-gamma-inducing factor) polyclonal Antibody
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| Product Synonym Names
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interleukin 18 (interferon-gamma-inducing factor); IL18; IGIF; IL-18; IL-1g; IL1F4; MGC12320
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| Product Gene Name
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[Similar Products]
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| Research Use Only
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For Research Use Only. Not for use in diagnostic procedures.
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 TOP
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| OMIM
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600953
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| Clonality
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Polyclonal
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| Isotype
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IgG
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| Host
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Rabbit
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| Species Reactivity
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Human
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| Purity/Purification
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Antigen Affinity Purified
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| Immunogen
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Human Pre-IL18
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| Storage Buffer
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PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
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| Santa Cruz Alternative
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Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-7954
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| ISO Certification
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Manufactured in an ISO 9001:2008 Certified Laboratory.
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| Other Notes
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Small volumes of anti-IL18 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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TOP
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| Applications Tested/Suitable for anti-IL18 antibody
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ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
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TOP
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| NCBI/Uniprot data below describe general gene information for IL18. It may not necessarily be applicable to this product. |
| NCBI GI #
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4504653
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| NCBI GeneID
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3606
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| NCBI Accession #
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NP_001553.1
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[Other Products]
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| NCBI GenBank Nucleotide #
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NM_001562.3
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[Other Products]
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| UniProt Secondary Accession #
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O75599; Q6FGY3; Q6WWJ7
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[Other Products]
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| UniProt Related Accession #
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Q14116
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[Other Products]
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| Molecular Weight
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21,896 Da
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[Similar Products]
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TOP
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| NCBI Official Full Name
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interleukin-18 isoform 1 proprotein
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| NCBI Official Synonym Full Names
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interleukin 18
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| NCBI Official Symbol
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IL18
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[Similar Products]
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| NCBI Official Synonym Symbols
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IGIF; IL-18; IL-1g; IL1F4
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[Similar Products]
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| NCBI Protein Information
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interleukin-18; IL-1 gamma; iboctadekin; interleukin-1 gamma; IFN-gamma-inducing factor; interleukin 18 (interferon-gamma-inducing factor)
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| UniProt Protein Name
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Interleukin-18
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| UniProt Synonym Protein Names
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Iboctadekin; Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; IL-1 gamma
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| Protein Family
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Interleukin
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| UniProt Gene Name
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IL18
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[Similar Products]
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| UniProt Synonym Gene Names
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IGIF; IL1F4; IL-18; IFN-gamma-inducing factor; IL-1 gamma
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[Similar Products]
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| UniProt Entry Name
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IL18_HUMAN
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| NCBI Summary for IL18
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The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity in spleen cells, and stimulates interferon gamma production in T-helper type I cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011]
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| UniProt Comments for IL18
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IL18: Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells. Belongs to the IL-1 family.
Protein type: Cytokine
Chromosomal Location of Human Ortholog: 11q22.2-q22.3
Cellular Component: extracellular space; extracellular region; cytosol
Molecular Function: protein binding; cytokine activity
Biological Process: positive regulation of granulocyte macrophage colony-stimulating factor production; positive regulation of NK T cell proliferation; natural killer cell activation; positive regulation of NF-kappaB import into nucleus; positive regulation of activated T cell proliferation; chemokine biosynthetic process; cell-cell signaling; lipopolysaccharide-mediated signaling pathway; granulocyte macrophage colony-stimulating factor biosynthetic process; angiogenesis; inflammatory response; regulation of cell adhesion; positive regulation of interleukin-17 production; T-helper 1 type immune response; positive regulation of natural killer cell proliferation; interleukin-2 biosynthetic process; T-helper 2 type immune response; MAPKKK cascade; interleukin-13 biosynthetic process; sleep; positive regulation of interferon-gamma production; positive regulation of tissue remodeling; interferon-gamma biosynthetic process; immune response; negative regulation of myoblast differentiation; positive regulation of inflammatory response
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TOP
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| Research Articles on IL18
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1. THP-1 monocyte-secreted IL-1beta/IL-18 promotes vascular smooth muscle cell proliferation.
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| Precautions
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All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
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| Disclaimer
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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| Products associated with anti-IL18 antibody | Pathways associated with anti-IL18 antibody |
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| Diseases associated with anti-IL18 antibody | Organs/Tissues associated with anti-IL18 antibody |
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TOP
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Antibody 
