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anti-KLHL3 antibody :: Rabbit kelch-like 3 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS711933 anti-KLHL3 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

kelch-like 3 (KLHL3), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-human kelch-like 3 (Drosophila) polyclonal Antibody

 Product Synonym Names    kelch-like 3 (Drosophila); KLHL3; FLJ40871; KIAA1129; MGC44594
 Product Gene Name   

anti-KLHL3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human,Mouse,Rat?Other species are not tested. Please decide the specificity by homology.
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 Purity/Purification    Antigen Affinity Purified
 Form/Format    Liquid
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 Immunogen    Human KLHL3
 Storage Buffer    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-133714
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-KLHL3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-KLHL3 antibody

   Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of ion transport in the distal nephron. The BCR(KLHL3) complex acts by mediating ubiquitination of WNK4, an inhibitor of potassium channel KCNJ1, leading to WNK4 degradation.
 Applications Tested/Suitable for anti-KLHL3 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-KLHL3 antibody    ELISA: Use at an assay dependent dilution.
WB: 1:200-1:2000
IHC: 1:50-1:200(Recommender dilutions)

Positive WB detected in: HepG2 cells, HL-60 cells, human liver tissue, Jurkat cells, mouse liver tissue, mouse thymus tissue, rat liver tissue
Positive IP detected in : HepG2 cells
Positive IHC detected in: Human liver tissue,human tonsillitis tissue
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NCBI/Uniprot data below describe general gene information for KLHL3. It may not necessarily be applicable to this product.
 NCBI GI #    197097330
 NCBI GeneID    100174246
 NCBI Accession #    NP_001127192.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001133720.1 [Other Products]
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 UniProt Related Accession #    Q5REP9 [Other Products]
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 NCBI Official Full Name    kelch-like protein 3
 NCBI Official Symbol    KLHL3 [Similar Products]
 NCBI Protein Information    kelch-like protein 3; kelch-like 3
 UniProt Protein Name    Kelch-like protein 3
 Protein Family    Kelch-like protein
 UniProt Gene Name    KLHL3 [Similar Products]
 UniProt Entry Name    KLHL3_PONAB
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 UniProt Comments for KLHL3    Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of ion transport in the distal nephron. The BCR(KLHL3) complex acts by mediating ubiquitination of WNK4, an inhibitor of potassium channel KCNJ1, leading to WNK4 degradation ().
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-KLHL3 antibodyOrgans/Tissues associated with anti-KLHL3 antibody
 Disease Name  Pubmed Publications
 Pseudohypoaldosteronism Antibodies  >20 publications with KLHL3 and Pseudohypoaldosteronism
 Cardiovascular Abnormalities Antibodies  >2 publications with KLHL3 and Cardiovascular Abnormalities
 Inflammation Antibodies  >1 publications with KLHL3 and Inflammation
 Disorders of Sex Development Antibodies  >1 publications with KLHL3 and Disorders of Sex Development
 Fibrosis Antibodies  >1 publications with KLHL3 and Fibrosis
 Congenital Abnormalities Antibodies  >1 publications with KLHL3 and Congenital Abnormalities
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >13 publications with KLHL3 and Kidney
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