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anti-LAX1 antibody :: Rabbit lymphocyte transmembrane adaptor 1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS712178 anti-LAX1 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

lymphocyte transmembrane adaptor 1 (LAX1), Polyclonal Antibody

 Also Known As   

Rabbit anti-human lymphocyte transmembrane adaptor 1 polyclonal Antibody

 Product Synonym Names    lymphocyte transmembrane adaptor 1; LAX1; FLJ20340; LAX
 Product Gene Name   

anti-LAX1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human LAX1
 Storage Buffer    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-161789
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-LAX1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-LAX1 antibody   

ELISA (EIA), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for LAX1. It may not necessarily be applicable to this product.
 NCBI GI #    63003901
 NCBI GeneID    54900
 NCBI Accession #    NP_060243.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_017773.3 [Other Products]
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 UniProt Secondary Accession #    Q6NSZ6; Q9NXB4; B7Z744; J3KP69 [Other Products]
 UniProt Related Accession #    Q8IWV1 [Other Products]
 Molecular Weight    42,491 Da [Similar Products]
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 NCBI Official Full Name    lymphocyte transmembrane adapter 1 isoform a
 NCBI Official Synonym Full Names    lymphocyte transmembrane adaptor 1
 NCBI Official Symbol    LAX1 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    lymphocyte transmembrane adapter 1; linker for activation of x cells; LAT-like membrane associated protein; membrane-associated adapter protein LAX
 UniProt Protein Name    Lymphocyte transmembrane adapter 1
 UniProt Synonym Protein Names   
Linker for activation of X cells; Membrane-associated adapter protein LAX
 Protein Family    Lymphocyte transmembrane adapter
 UniProt Gene Name    LAX1 [Similar Products]
 UniProt Synonym Gene Names    LAX [Similar Products]
 UniProt Entry Name    LAX1_HUMAN
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 UniProt Comments for LAX1    LAX1: Negatively regulates TCR (T-cell antigen receptor)- mediated signaling in T-cells and BCR (B-cell antigen receptor)- mediated signaling in B-cells. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q32.1

Cellular Component: Golgi apparatus; membrane; cytoplasm; plasma membrane; integral to membrane; lipid raft

Molecular Function: protein binding; SH2 domain binding; protein kinase binding

Biological Process: antigen receptor-mediated signaling pathway; B cell activation; immunoglobulin secretion; immune response; negative regulation of T cell activation; inactivation of MAPK activity
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 Research Articles on LAX1    1. TRIM required LAX for binding to Rab8 in a complex, a novel CTLA-4/TRIM/LAX/Rab8 effector complex in the transport of CTLA-4 to the surfaces of T cells
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-LAX1 antibodyDiseases associated with anti-LAX1 antibody
 Reference Product  PubMed Publications
 GRB2 antibody  >3 publications with LAX1 and GRB2
 LCK antibody  >2 publications with LAX1 and LCK
 HSH2D antibody  >2 publications with LAX1 and HSH2D
 SYK antibody  >1 publications with LAX1 and SYK
 Disease Name  Pubmed Publications
 Lung Neoplasms Antibodies  >1 publications with LAX1 and Lung Neoplasms
Organs/Tissues associated with anti-LAX1 antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >9 publications with LAX1 and Blood
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