NP_060243.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
lymphocyte transmembrane adapter 1 isoform a
NCBI Official Synonym Full Names
lymphocyte transmembrane adaptor 1
NCBI Official Synonym Symbols
NCBI Protein Information
lymphocyte transmembrane adapter 1; linker for activation of x cells; LAT-like membrane associated protein; membrane-associated adapter protein LAX
UniProt Protein Name
Lymphocyte transmembrane adapter 1
UniProt Synonym Protein Names
Linker for activation of X cells; Membrane-associated adapter protein LAX
UniProt Synonym Gene Names
UniProt Entry Name
LAX1_HUMAN
UniProt Comments for LAX1
LAX1: Negatively regulates TCR (T-cell antigen receptor)- mediated signaling in T-cells and BCR (B-cell antigen receptor)- mediated signaling in B-cells. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Adaptor/scaffold; Membrane protein, integral
Chromosomal Location of Human Ortholog: 1q32.1
Cellular Component: Golgi apparatus; membrane; cytoplasm; plasma membrane; integral to membrane; lipid raft
Molecular Function: protein binding; SH2 domain binding; protein kinase binding
Biological Process: antigen receptor-mediated signaling pathway; B cell activation; immunoglobulin secretion; immune response; negative regulation of T cell activation; inactivation of MAPK activity
Research Articles on LAX1
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Products associated with anti-LAX1 antibody
Diseases associated with anti-LAX1 antibody
Organs/Tissues associated with anti-LAX1 antibody
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