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anti-LPCAT4 antibody :: Rabbit lysophosphatidylcholine acyltransferase 4 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS711981 anti-LPCAT4 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

lysophosphatidylcholine acyltransferase 4 (LPCAT4), Polyclonal Antibody

 Also Known As   

Rabbit anti-human lysophosphatidylcholine acyltransferase 4 polyclonal Antibody

 Product Synonym Names    lysophosphatidylcholine acyltransferase 4; LPCAT4; AGPAT7; AYTL3; FLJ10257; LPAAT-eta; LPEAT2
 Product Gene Name   

anti-LPCAT4 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    612039
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human LPCAT4
 Storage Buffer    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-LPCAT4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-LPCAT4 antibody   

ELISA (EIA), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for LPCAT4. It may not necessarily be applicable to this product.
 NCBI GI #    62203469
 NCBI GeneID    254531
 NCBI Accession #    AAH92463.1 [Other Products]
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 UniProt Secondary Accession #    O43412; Q7Z4P4; Q8IUL7; Q8TB38; A8K2K8 [Other Products]
 UniProt Related Accession #    Q643R3 [Other Products]
 Molecular Weight    57,219 Da [Similar Products]
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 NCBI Official Full Name    Lysophosphatidylcholine acyltransferase 4
 NCBI Official Synonym Full Names    lysophosphatidylcholine acyltransferase 4
 NCBI Official Symbol    LPCAT4 [Similar Products]
 NCBI Official Synonym Symbols   
AYTL3; AGPAT7; LPEAT2; LPAAT-eta
[Similar Products]
 NCBI Protein Information    lysophospholipid acyltransferase LPCAT4; 1-AGPAT 7; plasmalogen synthase; acyltransferase like 3; acyltransferase-like 3; 1-AGP acyltransferase 7; PLSC domain containing protein; 1-acylglycerophosphoserine O-acyltransferase; 1-acylglycerophosphocholine O-acyltransferase; lysophosphatidylethanolamine acyltransferase 2; 1-alkylglycerophosphocholine O-acetyltransferase; 1-alkenylglycerophosphoethanolamine O-acyltransferase; acyl-CoA:lysophosphatidylethanolamine acyltransferase 2; 1-acylglycerol-3-phosphate O-acyltransferase 7 (lysophosphatidic acid acyltransferase, eta)
 UniProt Protein Name    Lysophospholipid acyltransferase LPCAT4
 UniProt Synonym Protein Names   
1-acylglycerol-3-phosphate O-acyltransferase 7; 1-AGP acyltransferase 7; 1-AGPAT 7; 1-acylglycerophosphocholine O-acyltransferase (EC:2.3.1.23); 1-acylglycerophosphoserine O-acyltransferase (EC:2.3.1.n6); 1-alkenylglycerophosphoethanolamine O-acyltransferase (EC:2.3.1.121); 1-alkylglycerophosphocholine O-acetyltransferase (EC:2.3.1.67); Acyltransferase-like 3; Lysophosphatidylcholine acyltransferase 4; Lysophosphatidylethanolamine acyltransferase 2 (EC:2.3.1.n7); Plasmalogen synthase
 Protein Family    Lysophospholipid acyltransferase
 UniProt Gene Name    LPCAT4 [Similar Products]
 UniProt Synonym Gene Names    AGPAT7; AYTL3; LPEAT2; 1-AGP acyltransferase 7; 1-AGPAT 7 [Similar Products]
 UniProt Entry Name    LPCT4_HUMAN
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 NCBI Summary for LPCAT4    Members of the 1-acylglycerol-3-phosphate O-acyltransferase (EC 2.3.1.51) family, such as AGPAT7, catalyze the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA), a precursor in the biosynthesis of all glycerolipids. Both LPA and PA are involved in signal transduction (Ye et al., 2005 [PubMed 16243729]).[supplied by OMIM, May 2008]
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 UniProt Comments for LPCAT4    AGPAT7: Displays acyl-CoA-dependent lysophospholipid acyltransferase activity with a subset of lysophospholipids as substrates; converts lysophosphatidylethanolamine to phosphatidylethanolamine, lysophosphatidylcholine to phosphatidycholine, 1-alkenyl-lysophatidylethanolamine to 1- alkenyl-phosphatidylethanolamine, lysophosphatidylglycerol and alkyl-lysophosphatidylcholine to phosphatidylglycerol and alkyl- phosphatidylcholine, respectively. In contrast, has no lysophosphatidylinositol, glycerol-3-phosphate, diacylglycerol or lysophosphatidic acid acyltransferase activity. Prefers long chain acyl-CoAs (C16, C18) as acyl donors. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

Protein type: EC 2.3.1.23; Transferase; EC 2.3.1.n6; EC 2.3.1.n7; Membrane protein, multi-pass; Membrane protein, integral; EC 2.3.1.67; EC 2.3.1.121

Chromosomal Location of Human Ortholog: 15q14

Cellular Component: endoplasmic reticulum membrane; membrane; endoplasmic reticulum; integral to membrane

Molecular Function: 1-alkylglycerophosphocholine O-acetyltransferase activity; 1-acylglycerophosphocholine O-acyltransferase activity; 1-alkenylglycerophosphoethanolamine O-acyltransferase activity

Biological Process: phospholipid metabolic process; glycerophospholipid biosynthetic process; phosphatidic acid biosynthetic process; triacylglycerol biosynthetic process; cellular lipid metabolic process
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 Research Articles on LPCAT4    1. LPCAT4 is overexpressed and involved in the deregulation of PC(16:0/16:1) in colorectal cancer.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-LPCAT4 antibodyPathways associated with anti-LPCAT4 antibody
 Reference Product  PubMed Publications
 LPCAT1 antibody  >2 publications with LPCAT4 and LPCAT1
 LPCAT2 antibody  >1 publications with LPCAT4 and LPCAT2
 Products by Pathway  Pathway Diagram
 Acyl Chain Remodelling Of PC Pathway antibodies  Acyl Chain Remodelling Of PC Pathway Diagram
 Acyl Chain Remodelling Of PE Pathway antibodies  Acyl Chain Remodelling Of PE Pathway Diagram
 Acyl Chain Remodelling Of PG Pathway antibodies  Acyl Chain Remodelling Of PG Pathway Diagram
 Acyl Chain Remodelling Of PS Pathway antibodies  Acyl Chain Remodelling Of PS Pathway Diagram
 CDP-diacylglycerol Biosynthesis I Pathway antibodies  CDP-diacylglycerol Biosynthesis I Pathway Diagram
 Ether Lipid Metabolism Pathway antibodies  Ether Lipid Metabolism Pathway Diagram
 Ether Lipid Metabolism Pathway antibodies  Ether Lipid Metabolism Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Glycerophospholipid Biosynthesis Pathway antibodies  Glycerophospholipid Biosynthesis Pathway Diagram
 Glycerophospholipid Metabolism Pathway antibodies  Glycerophospholipid Metabolism Pathway Diagram
Diseases associated with anti-LPCAT4 antibodyOrgans/Tissues associated with anti-LPCAT4 antibody
 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >2 publications with LPCAT4 and Fatty Liver
 Inflammation Antibodies  >1 publications with LPCAT4 and Inflammation
 Carcinoma, Hepatocellular Antibodies  >1 publications with LPCAT4 and Carcinoma, Hepatocellular
 Cholestasis Antibodies  >1 publications with LPCAT4 and Cholestasis
 Cholestasis, Intrahepatic Antibodies  >1 publications with LPCAT4 and Cholestasis, Intrahepatic
 Adenocarcinoma Antibodies  >1 publications with LPCAT4 and Adenocarcinoma
 Drug-Induced Liver Injury Antibodies  >1 publications with LPCAT4 and Drug-Induced Liver Injury
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >3 publications with LPCAT4 and Liver
 Nerve Antibodies  >1 publications with LPCAT4 and Nerve
 Muscle Antibodies  >1 publications with LPCAT4 and Muscle
 Pancreas Antibodies  >1 publications with LPCAT4 and Pancreas
 Thymus Antibodies  >1 publications with LPCAT4 and Thymus
 Kidney Antibodies  >1 publications with LPCAT4 and Kidney
 Uterus Antibodies  >1 publications with LPCAT4 and Uterus
 Lung Antibodies  >1 publications with LPCAT4 and Lung
 Stomach Antibodies  >1 publications with LPCAT4 and Stomach
 Intestine Antibodies  >1 publications with LPCAT4 and Intestine
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