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anti-D130043K22Rik antibody :: Goat mKIAA0319 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS422150
Western Blot (WB)
Unit / Price
0.1 mg  /  $300 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

mKIAA0319 (D130043K22Rik), Polyclonal Antibody

★Popular Item★
 Also Known As   

Goat anti-mKIAA0319 (mouse) Antibody

 Product Synonym Names    mKIAA0319; similar to KIAA0319 gene product; 4930451E12Rik; KIAA0319; mKIAA0319 antibody; similar to KIAA0319 gene product antibody; 4930451E12Rik antibody; KIAA0319 antibody; mKIAA0319 (mouse)
 Product Gene Name   

anti-D130043K22Rik antibody

[Similar Products]
 Product Synonym Gene Name    mKIAA0319 [Similar Products]
 Antibody/Peptide Pairs    mKIAA0319 peptide (MBS426999) is used for blocking the activity of mKIAA0319 antibody (MBS422150)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    QGKIKQENKP TLH
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 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Tested: Mouse; Expected from sequence similarity: Mouse, Rat
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 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
 Concentration    100ug specific antibody in 200ul (lot specific)
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 Immunogen    Peptide with sequence C-QGKIKQENKPTLH, from the internal region of the protein sequence according to NP_001074520.1.
 Epitope    Internal region
 Note    The variants XP_341528.2 and XP_001070349.1 represent identical protein. This antibody is expected to cross-react with mouse KIAA0319 isoform 1 (NP_001074520.1), isoform 2 (XP_994023.1) and isoform 4 (XP_913491.1).
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 Preparation and Storage    Aliquot and store at -20 degree C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-D130043K22Rik antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-D130043K22Rik antibody   

Peptide ELISA (EIA), Western Blot (WB)

 Application Notes for anti-D130043K22Rik antibody    Peptide ELISA: Antibody detection limit dilution 1: 128000.
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 Western Blot (WB) of anti-D130043K22Rik antibody    (0.5ug/ml) staining of Mouse Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
anti-D130043K22Rik antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for D130043K22Rik. It may not necessarily be applicable to this product.
 NCBI GI #    124486676
 NCBI GeneID    210108
 NCBI Accession #    NP_001074520.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001081051.2 [Other Products]
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 UniProt Secondary Accession #    Q14BF3; Q80U39 [Other Products]
 UniProt Related Accession #    Q5SZV5 [Other Products]
 Molecular Weight    117,988 Da
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 NCBI Official Full Name    dyslexia-associated protein KIAA0319 homolog
 NCBI Official Synonym Full Names    RIKEN cDNA D130043K22 gene
 NCBI Official Symbol    D130043K22Rik [Similar Products]
 NCBI Official Synonym Symbols   
Kiaa0319; 4930451E12Rik
[Similar Products]
 NCBI Protein Information    dyslexia-associated protein KIAA0319 homolog
 UniProt Protein Name    Dyslexia-associated protein KIAA0319 homolog
 UniProt Gene Name    Kiaa0319 [Similar Products]
 UniProt Entry Name    K0319_MOUSE
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 NCBI Summary for D130043K22Rik    This gene encodes a transmembrane protein that contains a large extracellular domain with multiple polycystic kidney disease (PKD) domains. The encoded protein may play a role in the development of the cerebral cortex by regulating neuronal migration and cell adhesion. Single nucleotide polymorphisms in a similar gene in human are associated with dyslexia. Alternatively spliced transcript variants have been identifed. [provided by RefSeq, May 2015]
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 UniProt Comments for D130043K22Rik    KIAA0319: Involved in neuronal migration during development of the cerebral neocortex. May function in a cell autonomous and a non- cell autonomous manner and play a role in appropriate adhesion between migrating neurons and radial glial fibers. May also regulate growth and differentiation of dendrites. Defects in KIAA0319 may be a cause of susceptibility to dyslexia type 2 (DYX2); also known as specific reading disability type 2. Dyslexia is a relatively common, complex cognitive disorder that affects 5% to 10% of school-aged children. The disorder is characterized by an impairment of reading performance despite adequate motivational, educational and intellectual opportunities and in the absence of sensory or neurological disability. A lower expression is associated with the risk haplotype. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Cellular Component: early endosome; endosome; integral to membrane; membrane; plasma membrane

Biological Process: multicellular organismal development; nervous system development; neuron migration
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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