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anti-MRI1 antibody :: Rabbit methylthioribose-1-phosphate isomerase homolog Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS716417 anti-MRI1 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

methylthioribose-1-phosphate isomerase homolog (MRI1), Polyclonal Antibody

 Also Known As   

Rabbit anti-human methylthioribose-1-phosphate isomerase homolog (S. cerevisiae) polyclonal Antibody

 Product Synonym Names    methylthioribose-1-phosphate isomerase homolog (S. cerevisiae); MRI1; MGC3207; MTNA; Ypr118wM1Pi; MRDI
 Product Gene Name   

anti-MRI1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    615105
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human MRI1
 Storage Buffer    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-240704
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-MRI1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-MRI1 antibody   

ELISA (EIA), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for MRI1. It may not necessarily be applicable to this product.
 NCBI GI #    72534748
 NCBI GeneID    84245
 NCBI Accession #    NP_001026897.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001031727.2 [Other Products]
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 UniProt Secondary Accession #    Q8NDC9 [Other Products]
 UniProt Related Accession #    Q9BV20 [Other Products]
 Molecular Weight    34,529 Da [Similar Products]
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 NCBI Official Full Name    methylthioribose-1-phosphate isomerase isoform 1
 NCBI Official Synonym Full Names    methylthioribose-1-phosphate isomerase 1
 NCBI Official Symbol    MRI1 [Similar Products]
 NCBI Official Synonym Symbols   
MRDI; MTNA; Ypr118w
[Similar Products]
 NCBI Protein Information    methylthioribose-1-phosphate isomerase; M1Pi; MRI1; MTR-1-P isomerase; mediator of RhoA-dependent invasion; S-methyl-5-thioribose-1-phosphate isomerase 1; methylthioribose-1-phosphate isomerase homolog; translation initiation factor eIF-2B subunit alpha/beta/delta-like protein
 UniProt Protein Name    Methylthioribose-1-phosphate isomerase
 UniProt Synonym Protein Names   
Mediator of RhoA-dependent invasionS-methyl-5-thioribose-1-phosphate isomerase; Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein
 Protein Family    Methylthioribose-1-phosphate isomerase
 UniProt Gene Name    MRI1 [Similar Products]
 UniProt Synonym Gene Names    M1Pi; MTR-1-P isomerase [Similar Products]
 UniProt Entry Name    MTNA_HUMAN
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 UniProt Comments for MRI1    MRI1: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover. Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 5.3.1.23; Isomerase

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: cell projection; cytoplasm; nucleolus; cytosol

Molecular Function: identical protein binding; S-methyl-5-thioribose-1-phosphate isomerase activity

Biological Process: methionine salvage; sulfur amino acid metabolic process; methionine biosynthetic process from S-adenosylmethionine; polyamine metabolic process
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 Research Articles on MRI1    1. Data indicate that the structural elements in MRDI distal from the MTR-1-P catalytic site are responsible for the invasion phenotype.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-MRI1 antibodyDiseases associated with anti-MRI1 antibody
 Products by Pathway  Pathway Diagram
 Cysteine And Methionine Metabolism Pathway antibodies  Cysteine And Methionine Metabolism Pathway Diagram
 Cysteine And Methionine Metabolism Pathway antibodies  Cysteine And Methionine Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram
 Metabolism Of Polyamines Pathway antibodies  Metabolism Of Polyamines Pathway Diagram
 Methionine Salvage Pathway antibodies  Methionine Salvage Pathway Diagram
 Methionine Salvage Pathway antibodies  Methionine Salvage Pathway Diagram
 Methionine Salvage Pathway antibodies  Methionine Salvage Pathway Diagram
 S-methyl-5-thio-alpha-D-ribose 1-phosphate Degradation Pathway antibodies  S-methyl-5-thio-alpha-D-ribose 1-phosphate Degradation Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >5 publications with MRI1 and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >4 publications with MRI1 and Cardiovascular Diseases
 Immune System Diseases Antibodies  >2 publications with MRI1 and Immune System Diseases
 Pancreatic Neoplasms Antibodies  >1 publications with MRI1 and Pancreatic Neoplasms
 Leukemia Antibodies  >1 publications with MRI1 and Leukemia
 Carcinoma Antibodies  >1 publications with MRI1 and Carcinoma
 Breast Neoplasms Antibodies  >1 publications with MRI1 and Breast Neoplasms
 Necrosis Antibodies  >1 publications with MRI1 and Necrosis
Organs/Tissues associated with anti-MRI1 antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >6 publications with MRI1 and Brain
 Blood Antibodies  >4 publications with MRI1 and Blood
 Bone Antibodies  >2 publications with MRI1 and Bone
 Eye Antibodies  >1 publications with MRI1 and Eye
 Connective Tissue Antibodies  >1 publications with MRI1 and Connective Tissue
 Skin Antibodies  >1 publications with MRI1 and Skin
 Testis Antibodies  >1 publications with MRI1 and Testis
 Intestine Antibodies  >1 publications with MRI1 and Intestine
 Lung Antibodies  >1 publications with MRI1 and Lung
 Placenta Antibodies  >1 publications with MRI1 and Placenta
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