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anti-MID2 antibody :: Rabbit midline 2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS713249 anti-MID2 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

midline 2 (MID2), Polyclonal Antibody

 Also Known As   

Rabbit anti-human midline 2 polyclonal Antibody

 Product Synonym Names    midline 2; MID2; FLJ37715; FLJ41813; FXY2; RNF60; TRIM1
 Product Gene Name   

anti-MID2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    300204
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human MID2
 Storage Buffer    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-55129 / sc-55130
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-MID2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-MID2 antibody   

ELISA (EIA), Immunohistochemistry (IHC)

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NCBI/Uniprot data below describe general gene information for MID2. It may not necessarily be applicable to this product.
 NCBI GI #    17389319
 NCBI GeneID    11043
 NCBI Accession #    AAH17707.1 [Other Products]
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 UniProt Secondary Accession #    Q5JYF5; Q8WWK1; Q9UJR9; A6NEL8; A6PVI5 [Other Products]
 UniProt Related Accession #    Q9UJV3 [Other Products]
 Molecular Weight    79,865 Da [Similar Products]
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 NCBI Official Full Name    Midline 2
 NCBI Official Synonym Full Names    midline 2
 NCBI Official Symbol    MID2 [Similar Products]
 NCBI Official Synonym Symbols   
FXY2; RNF60; TRIM1; MRX101
[Similar Products]
 NCBI Protein Information    probable E3 ubiquitin-protein ligase MID2; midin 2; midin-2; midline-2; midline defect 2; RING finger protein 60; tripartite motif protein 1; tripartite motif-containing protein 1
 UniProt Protein Name    Probable E3 ubiquitin-protein ligase MID2
 UniProt Synonym Protein Names   
Midin-2; Midline defect 2; Midline-2; RING finger protein 60; Tripartite motif-containing protein 1
 Protein Family    Cell wall integrity sensor
 UniProt Gene Name    MID2 [Similar Products]
 UniProt Synonym Gene Names    FXY2; RNF60; TRIM1 [Similar Products]
 UniProt Entry Name    TRIM1_HUMAN
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 NCBI Summary for MID2    The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to microtubular structures in the cytoplasm. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Feb 2009]
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 UniProt Comments for MID2    MID2: is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to microtubular structures in the cytoplasm. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Feb 2009]

Protein type: EC 6.3.2.-; Microtubule-binding; Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: Xq22.3

Cellular Component: microtubule; cytoplasm

Molecular Function: protein homodimerization activity; zinc ion binding; protein heterodimerization activity; microtubule binding; phosphoprotein binding; ligase activity

Biological Process: negative regulation of viral transcription; positive regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of virion penetration into host cell; innate immune response; protein ubiquitination; positive regulation of transcription factor activity; activation of NF-kappaB transcription factor

Disease: Mental Retardation, X-linked 101
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 Research Articles on MID2    1. A novel missense mutation (c.1040G>A, p.Arg347Gln) was reported in MID2, which encodes ubiquitin ligase E3, as the likely cause of X-linked mental retardation in a large kindred.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-MID2 antibodyDiseases associated with anti-MID2 antibody
 Reference Product  PubMed Publications
 MID1 antibody  >13 publications with MID2 and MID1
 Disease Name  Pubmed Publications
 Metabolic Diseases Antibodies  >4 publications with MID2 and Metabolic Diseases
 Nervous System Diseases Antibodies  >2 publications with MID2 and Nervous System Diseases
 Lung Diseases Antibodies  >2 publications with MID2 and Lung Diseases
 Heart Diseases Antibodies  >1 publications with MID2 and Heart Diseases
 Urogenital Abnormalities Antibodies  >1 publications with MID2 and Urogenital Abnormalities
 Ovarian Neoplasms Antibodies  >1 publications with MID2 and Ovarian Neoplasms
 Mental Disorders Antibodies  >1 publications with MID2 and Mental Disorders
 Eye Diseases Antibodies  >1 publications with MID2 and Eye Diseases
 Fibrosis Antibodies  >1 publications with MID2 and Fibrosis
Organs/Tissues associated with anti-MID2 antibody
 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >3 publications with MID2 and Embryonic Tissue
 Eye Antibodies  >1 publications with MID2 and Eye
 Lung Antibodies  >1 publications with MID2 and Lung
 Muscle Antibodies  >1 publications with MID2 and Muscle
 Brain Antibodies  >1 publications with MID2 and Brain
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