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anti-MECR antibody :: Rabbit mitochondrial trans-2-enoyl-CoA reductase Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS714294 anti-MECR antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

mitochondrial trans-2-enoyl-CoA reductase (MECR), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-human mitochondrial trans-2-enoyl-CoA reductase polyclonal Antibody

 Product Synonym Names    mitochondrial trans-2-enoyl-CoA reductase; MECR; CGI-63; FASN2B; NRBF1
 Product Gene Name   

anti-MECR antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    608205
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human MECR
 Storage Buffer    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-160510
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-MECR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-MECR antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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NCBI/Uniprot data below describe general gene information for MECR. It may not necessarily be applicable to this product.
 NCBI GI #    12655133
 NCBI GeneID    51102
 NCBI Accession #    AAH01419.1 [Other Products]
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 UniProt Secondary Accession #    Q5SYU0; Q5SYU1; Q5SYU2; Q6IBU9; Q9Y373; B3KT72 [Other Products]
 UniProt Related Accession #    Q9BV79 [Other Products]
 Molecular Weight    32,228 Da [Similar Products]
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 NCBI Official Full Name    Mitochondrial trans-2-enoyl-CoA reductase
 NCBI Official Synonym Full Names    mitochondrial trans-2-enoyl-CoA reductase
 NCBI Official Symbol    MECR [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    trans-2-enoyl-CoA reductase, mitochondrial; nuclear receptor binding factor 1; mitochondrial 2-enoyl thioester reductase; homolog of yeast 2-enoyl thioester reductase
 UniProt Protein Name    Trans-2-enoyl-CoA reductase, mitochondrial
 UniProt Synonym Protein Names   
Nuclear receptor-binding factor 1; HsNrbf-1; NRBF-1
 UniProt Gene Name    MECR [Similar Products]
 UniProt Synonym Gene Names    NBRF1; HsNrbf-1; NRBF-1 [Similar Products]
 UniProt Entry Name    MECR_HUMAN
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 UniProt Comments for MECR    MECR: Catalyzes the reduction of trans-2-enoyl-CoA to acyl-CoA with chain length from C6 to C16 in an NADPH-dependent manner with preference to medium chain length substrate. May have a role in the mitochondrial synthesis of fatty acids. Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC; Oxidoreductase; Lipid Metabolism - fatty acid elongation in mitochondria

Chromosomal Location of Human Ortholog: 1p35.3

Cellular Component: mitochondrion; nucleus

Molecular Function: zinc ion binding; trans-2-enoyl-CoA reductase (NADPH) activity

Biological Process: fatty acid metabolic process; fatty acid biosynthetic process
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 Research Articles on MECR    1. overexpression of MECR, the last step in the mitochondrial fatty acid synthesis (mtFASII) pathway, causes modulation of gene expression through the PPAR pathway.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-MECR antibodyDiseases associated with anti-MECR antibody
 Products by Pathway  Pathway Diagram
 Fatty Acid Biosynthesis Pathway antibodies  Fatty Acid Biosynthesis Pathway Diagram
 Fatty Acid Biosynthesis, Elongation, Mitochondria Pathway antibodies  Fatty Acid Biosynthesis, Elongation, Mitochondria Pathway Diagram
 Fatty Acid Biosynthesis, Elongation, Mitochondria Pathway antibodies  Fatty Acid Biosynthesis, Elongation, Mitochondria Pathway Diagram
 Fatty Acid Elongation Pathway antibodies  Fatty Acid Elongation Pathway Diagram
 Fatty Acid Elongation Pathway antibodies  Fatty Acid Elongation Pathway Diagram
 Fatty Acid Metabolism Pathway antibodies  Fatty Acid Metabolism Pathway Diagram
 Fatty Acid Metabolism Pathway antibodies  Fatty Acid Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >1 publications with MECR and Carcinoma
 Cardiovascular Diseases Antibodies  >1 publications with MECR and Cardiovascular Diseases
 Weight Loss Antibodies  >1 publications with MECR and Weight Loss
Organs/Tissues associated with anti-MECR antibody
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >3 publications with MECR and Kidney
 Liver Antibodies  >1 publications with MECR and Liver
 Muscle Antibodies  >1 publications with MECR and Muscle
 Blood Antibodies  >1 publications with MECR and Blood
 Brain Antibodies  >1 publications with MECR and Brain
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