NP_000611.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 120 kDa Predicted: 161 kDa
NCBI Official Full Name
nitric oxide synthase, brain isoform 1
NCBI Official Synonym Full Names
nitric oxide synthase 1
NCBI Official Synonym Symbols
NOS; bNOS; nNOS; IHPS1; N-NOS; NC-NOS [Similar Products]
NCBI Protein Information
nitric oxide synthase, brain
UniProt Protein Name
Nitric oxide synthase, brain
UniProt Synonym Protein Names
Constitutive NOS; NC-NOS; NOS type I; Neuronal NOS; N-NOS; nNOS; Peptidyl-cysteine S-nitrosylase NOS1; bNOS
UniProt Synonym Gene Names
NCBI Summary for nNOS
The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.[provided by RefSeq, Feb 2011]
UniProt Comments for nNOS
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.
Research Articles on nNOS
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Products associated with anti-nNOS antibody
Pathways associated with anti-nNOS antibody
Diseases associated with anti-nNOS antibody
Organs/Tissues associated with anti-nNOS antibody
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