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anti-NGB antibody :: Rabbit neuroglobin Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS713752 anti-NGB antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

neuroglobin (NGB), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-human neuroglobin polyclonal Antibody

 Product Synonym Names    neuroglobin;
 Product Gene Name   

anti-NGB antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    605304
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human NGB
 Storage Buffer    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-22001 / sc-30144
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-NGB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-NGB antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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NCBI/Uniprot data below describe general gene information for NGB. It may not necessarily be applicable to this product.
 NCBI GI #    10864065
 NCBI GeneID    58157
 NCBI Accession #    NP_067080.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_021257.3 [Other Products]
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 UniProt Related Accession #    Q9NPG2 [Other Products]
 Molecular Weight    16,933 Da [Similar Products]
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 NCBI Official Full Name    neuroglobin
 NCBI Official Synonym Full Names    neuroglobin
 NCBI Official Symbol    NGB [Similar Products]
 NCBI Protein Information    neuroglobin
 UniProt Protein Name    Neuroglobin
 Protein Family    Neuroglobin
 UniProt Gene Name    NGB [Similar Products]
 UniProt Entry Name    NGB_HUMAN
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 NCBI Summary for NGB    This gene encodes an oxygen-binding protein that is distantly related to members of the globin gene family. It is highly conserved among other vertebrates. It is expressed in the central and peripheral nervous system where it may be involved in increasing oxygen availability and providing protection under hypoxic/ischemic conditions. [provided by RefSeq, Jul 2008]
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 UniProt Comments for NGB    NGB: Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative stress. May exert its anti-apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis. Belongs to the globin family.

Chromosomal Location of Human Ortholog: 14q24.3

Cellular Component: mitochondrion; perikaryon

Molecular Function: iron ion binding; heme binding; oxygen binding; oxygen transporter activity

Biological Process: oxygen transport; apoptosis
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 Research Articles on NGB    1. analysis of single nucleotide polymorphisms in neuroglobin that affect transcription and possibly Alzheimer's Disease
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-NGB antibodyDiseases associated with anti-NGB antibody
 Reference Product  PubMed Publications
 RAC1 antibody  >1 publications with NGB and RAC1
 AHSP antibody  >1 publications with NGB and AHSP
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >55 publications with NGB and Nervous System Diseases
 Brain Diseases Antibodies  >43 publications with NGB and Brain Diseases
 Cardiovascular Diseases Antibodies  >24 publications with NGB and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >18 publications with NGB and Disease Models, Animal
 Neurodegenerative Diseases Antibodies  >16 publications with NGB and Neurodegenerative Diseases
 Urinary Bladder Diseases Antibodies  >11 publications with NGB and Urinary Bladder Diseases
 Hypertension Antibodies  >6 publications with NGB and Hypertension
 Alzheimer Disease Antibodies  >5 publications with NGB and Alzheimer Disease
 Immune System Diseases Antibodies  >4 publications with NGB and Immune System Diseases
 Congenital Abnormalities Antibodies  >4 publications with NGB and Congenital Abnormalities
Organs/Tissues associated with anti-NGB antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >136 publications with NGB and Brain
 Eye Antibodies  >17 publications with NGB and Eye
 Embryonic Tissue Antibodies  >5 publications with NGB and Embryonic Tissue
 Lung Antibodies  >5 publications with NGB and Lung
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