EAX08719.1
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
nuclear fragile X mental retardation protein interacting protein 1
NCBI Official Synonym Full Names
nuclear fragile X mental retardation protein interacting protein 1
NCBI Protein Information
nuclear fragile X mental retardation-interacting protein 1; nuclear FMRP-interacting protein 1
UniProt Protein Name
Nuclear fragile X mental retardation-interacting protein 1
UniProt Synonym Protein Names
Nuclear FMRP-interacting protein 1
UniProt Entry Name
NUFP1_HUMAN
NCBI Summary for NUFIP1
This gene encodes a nuclear RNA binding protein that contains a C2H2 zinc finger motif and a nuclear localization signal. This protein is associated with the nuclear matrix in perichromatin fibrils and, in neurons, localizes to the cytoplasm in association with endoplasmic reticulum ribosomes. This protein interacts with the fragile X mental retardation protein (FMRP), the tumor suppressor protein BRCA1, upregulates RNA polymerase II transcription, and is involved in box C/D snoRNP biogenesis. A pseudogene of this gene resides on chromosome 6q12. [provided by RefSeq, Feb 2012]
UniProt Comments for NUFIP1
NUFIP1: Binds RNA.
Protein type: Transcription initiation complex; C2H2-type zinc finger protein
Chromosomal Location of Human Ortholog: 13q14
Cellular Component: nucleoplasm; transcription elongation factor complex; protein complex; nuclear matrix; perichromatin fibrils; nucleolus; presynaptic active zone; nucleus
Molecular Function: protein binding, bridging; snoRNA binding; identical protein binding; protein binding; DNA binding; RNA binding; metal ion binding
Biological Process: RNA processing; box C/D snoRNP assembly; positive regulation of transcription from RNA polymerase II promoter
Research Articles on NUFIP1
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Products associated with anti-NUFIP1 antibody
Diseases associated with anti-NUFIP1 antibody
Organs/Tissues associated with anti-NUFIP1 antibody
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