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anti-p23 antibody :: Rabbit p23 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2535608
Western Blot (WB)
Unit / Price
0.02 mL  /  $110 +1 FREE 8GB USB
0.06 mL  /  $150 +1 FREE 8GB USB
0.12 mL  /  $225 +1 FREE 8GB USB
0.2 mL  /  $360 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

p23, Polyclonal Antibody

★Popular Item★
 Also Known As   

p23 Polyclonal Antibody

 Product Synonym Names    PTGES3; P23; TEBP; Prostaglandin E synthase 3; Cytosolic prostaglandin E2 synthase; cPGES; Hsp90 co-chaperone; Progesterone receptor complex p23; Telomerase-binding protein p23
 Product Gene Name   

anti-p23 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    607061
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
 Concentration    1 mg/ml (lot specific)
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 Immunogen    Synthesized peptide derived from human p23 around the non-phosphorylation site of S113.
 Buffer    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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 Preparation and Storage    Store at -20 degree C. Avoid freeze / thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-p23 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-p23 antibody    Cancer
 Applications Tested/Suitable for anti-p23 antibody   

Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)

 Application Notes for anti-p23 antibody    WB: 1:500-1:2000, IHC: 1:50-1:200, ELISA: 1:5000-1:20000
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 Western Blot (WB) of anti-p23 antibody    Western Blot analysis of various cells using p23 Polyclonal Antibody at dilution of 1:2000.
anti-p23 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for p23. It may not necessarily be applicable to this product.
 NCBI GI #    438652
 NCBI GeneID    10728
 NCBI Accession #    AAA18537.1 [Other Products]
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 UniProt Secondary Accession #    Q8WU70; A8K7D0; B4DHP2; B4DP11; B4DP21 [Other Products]
 UniProt Related Accession #    Q15185 [Other Products]
 Molecular Weight    Calculated MW: 19
Observed MW: 24
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 NCBI Official Full Name    p23
 NCBI Official Synonym Full Names    prostaglandin E synthase 3
 NCBI Official Symbol    PTGES3 [Similar Products]
 NCBI Official Synonym Symbols   
P23; TEBP; cPGES
[Similar Products]
 NCBI Protein Information    prostaglandin E synthase 3
 UniProt Protein Name    Prostaglandin E synthase 3
 UniProt Synonym Protein Names   
Cytosolic prostaglandin E2 synthase; cPGES; Hsp90 co-chaperone; Progesterone receptor complex p23; Telomerase-binding protein p23
 UniProt Gene Name    PTGES3 [Similar Products]
 UniProt Synonym Gene Names    P23; TEBP; cPGES [Similar Products]
 UniProt Entry Name    TEBP_HUMAN
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 NCBI Summary for p23    This gene encodes an enzyme that converts prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). This protein functions as a co-chaperone with heat shock protein 90 (HSP90), localizing to response elements in DNA and disrupting transcriptional activation complexes. Alternative splicing results in multiple transcript variants. There are multiple pseudogenes of this gene on several different chromosomes. [provided by RefSeq, Feb 2016]
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 UniProt Comments for p23    TEBP: Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor- mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Belongs to the p23/wos2 family.

Protein type: EC 5.3.99.3; Nuclear receptor co-regulator; Isomerase; Transferase; Chaperone

Chromosomal Location of Human Ortholog: 12q13.3|12

Cellular Component: chromosome, telomeric region; cytoplasm; cytosol; nucleoplasm; nucleus; telomerase holoenzyme complex

Molecular Function: prostaglandin-E synthase activity; protein binding; telomerase activity; unfolded protein binding

Biological Process: arachidonic acid metabolic process; cyclooxygenase pathway; prostaglandin biosynthetic process; RNA-dependent DNA replication; signal transduction; telomere maintenance
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 Research Articles on p23    1. increased p23 expression may allow cells to acquire a more aggressive phenotype, contributing to disease progression
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-p23 antibodyPathways associated with anti-p23 antibody
 Reference Product  PubMed Publications
 PTGS2 antibody  >8 publications with p23 and PTGS2
 PTGES2 antibody  >8 publications with p23 and PTGES2
 PTGS1 antibody  >4 publications with p23 and PTGS1
 STIP1 antibody  >3 publications with p23 and STIP1
 HSP90AA1 antibody  >3 publications with p23 and HSP90AA1
 FKBP4 antibody  >2 publications with p23 and FKBP4
 TERT antibody  >1 publications with p23 and TERT
 Products by Pathway  Pathway Diagram
 AhR Pathway antibodies  AhR Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Attenuation Phase Pathway antibodies  Attenuation Phase Pathway Diagram
 C20 Prostanoid Biosynthesis Pathway antibodies  C20 Prostanoid Biosynthesis Pathway Diagram
 C20 Prostanoid Biosynthesis Pathway antibodies  C20 Prostanoid Biosynthesis Pathway Diagram
 Cellular Response To Heat Stress Pathway antibodies  Cellular Response To Heat Stress Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 HSF1 Activation Pathway antibodies  HSF1 Activation Pathway Diagram
Diseases associated with anti-p23 antibodyOrgans/Tissues associated with anti-p23 antibody
 Disease Name  Pubmed Publications
 Chromosome Aberrations Antibodies  >2 publications with p23 and Chromosome Aberrations
 Lung Diseases Antibodies  >2 publications with p23 and Lung Diseases
 Carcinoma Antibodies  >2 publications with p23 and Carcinoma
 Cardiomegaly Antibodies  >1 publications with p23 and Cardiomegaly
 Lung Neoplasms Antibodies  >1 publications with p23 and Lung Neoplasms
 Neoplasm Metastasis Antibodies  >1 publications with p23 and Neoplasm Metastasis
 Liver Neoplasms Antibodies  >1 publications with p23 and Liver Neoplasms
 Immune System Diseases Antibodies  >1 publications with p23 and Immune System Diseases
 Heart Diseases Antibodies  >1 publications with p23 and Heart Diseases
 Vascular Diseases Antibodies  >1 publications with p23 and Vascular Diseases
 Organ/Tissue Name  Pubmed Publications
 Uterus Antibodies  >3 publications with p23 and Uterus
 Vascular Antibodies  >2 publications with p23 and Vascular
 Ovary Antibodies  >2 publications with p23 and Ovary
 Lung Antibodies  >2 publications with p23 and Lung
 Brain Antibodies  >2 publications with p23 and Brain
 Heart Antibodies  >1 publications with p23 and Heart
 Muscle Antibodies  >1 publications with p23 and Muscle
 Liver Antibodies  >1 publications with p23 and Liver
 Embryonic Tissue Antibodies  >1 publications with p23 and Embryonic Tissue
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