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anti-p47-phox antibody :: Rabbit anti-Human p47 phox Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9503394
Unit / Price
0.05 mg  /  $225 +1 FREE 8GB USB
0.1 mg  /  $310 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

p47 phox (p47-phox), Polyclonal Antibody

★Popular Item★
 Also Known As   

p47 phox (Phospho-Ser345) Antibody

 Product Synonym Names    47 kDa autosomal chronic granulomatous disease protein; 47 kDa neutrophil oxidase factor; NCF-1; NCF-47K; NCF1; Neutrophil cytosol factor 1; Neutrophil cytosolic factor 1; Neutrophil NADPH oxidase factor 1; P47 phox
 Product Gene Name   

anti-p47-phox antibody

[Similar Products]
 Product Synonym Gene Name    NCF1 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    M25665 mRNA
 3D Structure    ModBase 3D Structure for P14598
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    p47 phox (Phospho-Ser345) Antibody detects endogenous levels of p47 phox only when phosphorylated at Ser345.
 Purity/Purification    Purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
 Form/Format    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
 Concentration    1 mg/ml (lot specific)
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 Target Modification    Phospho
 Modification Sites    H:S345
 Immunogen    The antiserum was produced against synthesized peptide derived from human p47 phox around the phosphorylation site of Ser345.
 Immunogen Range    311-360
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 Preparation and Storage    Stable at -20 degree C for at least 1 year.
 Other Notes    Small volumes of anti-p47-phox antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-p47-phox antibody   

Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)

 Application Notes for anti-p47-phox antibody    WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:1000
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 Immunohistochemistry (IHC) of anti-p47-phox antibody    Immunohistochemistry analysis of paraffin-embedded human brain, using p47 phox (Phospho-Ser345) Antibody. The picture on the right is blocked with the phospho peptide.
anti-p47-phox antibody Immunohistochemistry (IHC) (IHC) image
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 Western Blot (WB) of anti-p47-phox antibody    Western blot analysis of lysates from HepG2 cells treated with TNF 20ng/ml 5', using p47 phox (Phospho-Ser345) Antibody. The lane on the right is blocked with the phospho peptide.
anti-p47-phox antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for p47-phox. It may not necessarily be applicable to this product.
 NCBI GI #    528078313
 NCBI GeneID    653361
 NCBI Accession #    NP_000256.4 [Other Products]
 NCBI GenBank Nucleotide #    NM_000265.5 [Other Products]
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 UniProt Primary Accession #    P14598 [Other Products]
 UniProt Secondary Accession #    O43842; Q2PP07; Q53FR5; Q9BU90; Q9BXI7; Q9BXI8; Q9UDV9; Q9UMU2; A6NEH2; A8K7S9 [Other Products]
 UniProt Related Accession #    P14598 [Other Products]
 Molecular Weight    44 kDa
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 NCBI Official Full Name    neutrophil cytosol factor 1
 NCBI Official Synonym Full Names    neutrophil cytosolic factor 1
 NCBI Official Symbol    NCF1 [Similar Products]
 NCBI Official Synonym Symbols   
NCF1A; NOXO2; p47phox; SH3PXD1A
[Similar Products]
 NCBI Protein Information    neutrophil cytosol factor 1
 UniProt Protein Name    Neutrophil cytosol factor 1
 UniProt Synonym Protein Names   
47 kDa autosomal chronic granulomatous disease protein; 47 kDa neutrophil oxidase factor; NCF-47K; Neutrophil NADPH oxidase factor 1; Nox organizer 2; Nox-organizing protein 2; SH3 and PX domain-containing protein 1A; p47-phox
 UniProt Gene Name    NCF1 [Similar Products]
 UniProt Synonym Gene Names    NOXO2; SH3PXD1A; NCF-1 [Similar Products]
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 NCBI Summary for p47-phox    The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease. [provided by RefSeq, Jul 2008]
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 UniProt Comments for p47-phox    NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).
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 Research Articles on p47-phox    1. Decreased and increased copy numbers of NCF1 predispose to and protect against SLE.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-p47-phox antibodyDiseases associated with anti-p47-phox antibody
 Products by Pathway  Pathway Diagram
 AGE/RAGE Pathway antibodies  AGE/RAGE Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Antigen Processing-Cross Presentation Pathway antibodies  Antigen Processing-Cross Presentation Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class I MHC Mediated Antigen Processing & Presentation Pathway antibodies  Class I MHC Mediated Antigen Processing & Presentation Pathway Diagram
 Cross-presentation Of Particulate Exogenous Antigens (phagosomes) Pathway antibodies  Cross-presentation Of Particulate Exogenous Antigens (phagosomes) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Fc Gamma R-mediated Phagocytosis Pathway antibodies  Fc Gamma R-mediated Phagocytosis Pathway Diagram
 Fc Gamma R-mediated Phagocytosis Pathway antibodies  Fc Gamma R-mediated Phagocytosis Pathway Diagram
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >47 publications with p47-phox and Inflammation
 Disease Models, Animal Antibodies  >40 publications with p47-phox and Disease Models, Animal
 Arthritis, Rheumatoid Antibodies  >24 publications with p47-phox and Arthritis, Rheumatoid
 Cardiovascular Diseases Antibodies  >11 publications with p47-phox and Cardiovascular Diseases
 Heart Diseases Antibodies  >8 publications with p47-phox and Heart Diseases
 Necrosis Antibodies  >7 publications with p47-phox and Necrosis
 Hypertension Antibodies  >5 publications with p47-phox and Hypertension
 Liver Diseases Antibodies  >3 publications with p47-phox and Liver Diseases
 Diabetes Mellitus, Experimental Antibodies  >3 publications with p47-phox and Diabetes Mellitus, Experimental
 Atherosclerosis Antibodies  >2 publications with p47-phox and Atherosclerosis
Organs/Tissues associated with anti-p47-phox antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >51 publications with p47-phox and Blood
 Lung Antibodies  >10 publications with p47-phox and Lung
 Lymph Antibodies  >7 publications with p47-phox and Lymph
 Lymph Node Antibodies  >7 publications with p47-phox and Lymph Node
 Spleen Antibodies  >6 publications with p47-phox and Spleen
 Brain Antibodies  >4 publications with p47-phox and Brain
 Skin Antibodies  >4 publications with p47-phox and Skin
 Kidney Antibodies  >3 publications with p47-phox and Kidney
 Connective Tissue Antibodies  >2 publications with p47-phox and Connective Tissue
 Placenta Antibodies  >1 publications with p47-phox and Placenta
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