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anti-p73 antibody :: Rabbit anti-Human p73 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2534636
Unit / Price
0.02 mL  /  $110 +1 FREE 8GB USB
0.06 mL  /  $150 +1 FREE 8GB USB
0.12 mL  /  $225 +1 FREE 8GB USB
0.2 mL  /  $360 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

p73, Polyclonal Antibody

★Popular Item★
 Also Known As   

p73 Polyclonal Antibody

 Product Synonym Names    TP73; P73; Tumor protein p73; p53-like transcription factor; p53-related protein
 Product Gene Name   

anti-p73 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    601990
 3D Structure    ModBase 3D Structure for O15350
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Antigen Affinity Purified
 Concentration    1 mg/ml (lot specific)
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 Immunogen    Synthesized peptide derived from human p73 around the non-acetylation site of K321.
 Buffer    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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 Preparation and Storage    Store at -20 degree C. Avoid freeze / thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-p73 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-p73 antibody    Cancer; Cell biology; Epigenetics
 Applications Tested/Suitable for anti-p73 antibody   

Western Blot (WB), ELISA (EIA)

 Application Notes for anti-p73 antibody    WB: 1:500-1:2000, ELISA: 1:5000-1:20000
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 Western Blot (WB) of anti-p73 antibody    Western Blot analysis of Jurkat cells with p73 Polyclonal Antibody.
anti-p73 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-p73 antibody    Immunohistochemistry of paraffin-embedded Human lymph gland tissue using p73 Polyclonal Antibody at dilution of 1:100.
anti-p73 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for p73. It may not necessarily be applicable to this product.
 NCBI GI #    2370178
 NCBI GeneID    7161
 NCBI Accession #    CAA72221.1 [Other Products]
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 UniProt Primary Accession #    O15350 [Other Products]
 UniProt Secondary Accession #    O15351; Q17RN8; Q5TBV5; Q5TBV6; Q8NHW9; Q8TDY5; Q8TDY6; B7Z7J4; B7Z8Z1; B7Z9C1; C9J521 [Other Products]
 UniProt Related Accession #    O15350 [Other Products]
 Molecular Weight    Calculated MW: 70
Observed MW: 70
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 NCBI Official Full Name    P73
 NCBI Official Synonym Full Names    tumor protein p73
 NCBI Official Symbol    TP73 [Similar Products]
 NCBI Official Synonym Symbols   
P73
[Similar Products]
 NCBI Protein Information    tumor protein p73
 UniProt Protein Name    Tumor protein p73
 UniProt Synonym Protein Names   
p53-like transcription factor; p53-related protein
 UniProt Gene Name    TP73 [Similar Products]
 UniProt Synonym Gene Names    P73 [Similar Products]
 UniProt Entry Name    P73_HUMAN
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 NCBI Summary for p73    This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined. [provided by RefSeq, Feb 2011]
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 UniProt Comments for p73    Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
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 Research Articles on p73    1. data support the hypothesis that the DeltaNp73/TAp73 ratio is an important determinant of clinical response in APL and may offer a therapeutic target for enhancing chemosensitivity in blast cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-p73 antibodyPathways associated with anti-p73 antibody
 Reference Product  PubMed Publications
 E2F1 antibody  >7 publications with p73 and E2F1
 MDM2 antibody  >6 publications with p73 and MDM2
 MYC antibody  >4 publications with p73 and MYC
 YAP1 antibody  >1 publications with p73 and YAP1
 Products by Pathway  Pathway Diagram
 Alpha6-Beta4 Integrin Signaling Pathway antibodies  Alpha6-Beta4 Integrin Signaling Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 DNA Damage Response (only ATM Dependent) Pathway antibodies  DNA Damage Response (only ATM Dependent) Pathway Diagram
 Direct P53 Effectors Pathway antibodies  Direct P53 Effectors Pathway Diagram
 E2F Transcription Factor Network Pathway antibodies  E2F Transcription Factor Network Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Measles Pathway antibodies  Measles Pathway Diagram
 Measles Pathway antibodies  Measles Pathway Diagram
 Neurotrophin Signaling Pathway antibodies  Neurotrophin Signaling Pathway Diagram
Diseases associated with anti-p73 antibody
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >52 publications with p73 and Carcinoma
 Carcinoma, Squamous Cell Antibodies  >16 publications with p73 and Carcinoma, Squamous Cell
 Chromosome Aberrations Antibodies  >16 publications with p73 and Chromosome Aberrations
 Cell Transformation, Neoplastic Antibodies  >15 publications with p73 and Cell Transformation, Neoplastic
 Head and Neck Neoplasms Antibodies  >15 publications with p73 and Head and Neck Neoplasms
 Neoplasms, Experimental Antibodies  >15 publications with p73 and Neoplasms, Experimental
 Colorectal Neoplasms Antibodies  >13 publications with p73 and Colorectal Neoplasms
 Breast Neoplasms Antibodies  >12 publications with p73 and Breast Neoplasms
 Leukemia Antibodies  >10 publications with p73 and Leukemia
 Lung Neoplasms Antibodies  >8 publications with p73 and Lung Neoplasms
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