AAH24648.1
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Phosphohistidine phosphatase 1
NCBI Official Synonym Full Names
phosphohistidine phosphatase 1
NCBI Official Synonym Symbols
PHP14; CGI-202; HSPC141; HEL-S-132P [Similar Products]
NCBI Protein Information
14 kDa phosphohistidine phosphatase; protein janus-A homolog; sex-regulated protein janus-a; epididymis secretory sperm binding protein Li 132P
UniProt Protein Name
14 kDa phosphohistidine phosphatase
UniProt Synonym Protein Names
Phosphohistidine phosphatase 1; Protein janus-A homolog
UniProt Synonym Gene Names
UniProt Entry Name
PHP14_HUMAN
NCBI Summary for PHPT1
This gene encodes an enzyme that catalyzes the reversible dephosphorylation of histidine residues in proteins. It may be involved in the dephosphorylation of G-beta and ATP citrate lyase and in negatively regulating CD4 T lymphocytes by dephosphorylation and inhibition of KCa3.1 channels. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
UniProt Comments for PHPT1
PHPT1: a phosphohistidine phosphatase. Present preferentially in heart and skeletal muscle. Insensitive to inhibition by okadaic acid and EDTA.
Protein type: Carbohydrate Metabolism - fructose and mannose; Phosphatase; Motility/polarity/chemotaxis; Cofactor and Vitamin Metabolism - thiamine; EC 3.1.3.-; Cofactor and Vitamin Metabolism - riboflavin
Chromosomal Location of Human Ortholog: 9q34.3
Cellular Component: cytosol
Molecular Function: calcium channel inhibitor activity; phosphohistidine phosphatase activity; phosphoprotein phosphatase activity
Biological Process: negative regulation of T cell receptor signaling pathway; negative regulation of lyase activity; protein amino acid dephosphorylation
Research Articles on PHPT1
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Products associated with anti-PHPT1 antibody
Pathways associated with anti-PHPT1 antibody
Diseases associated with anti-PHPT1 antibody
Organs/Tissues associated with anti-PHPT1 antibody
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