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anti-PAFAH2 antibody :: Rabbit platelet-activating factor acetylhydrolase 2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS714725 anti-PAFAH2 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

platelet-activating factor acetylhydrolase 2 (PAFAH2), Polyclonal Antibody

 Also Known As   

Rabbit anti-human platelet-activating factor acetylhydrolase 2, 40kDa polyclonal Antibody

 Product Synonym Names    platelet-activating factor acetylhydrolase 2; 40kDa; PAFAH2; FLJ26025; HSD-PLA2
 Product Gene Name   

anti-PAFAH2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    602344
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human PAFAH2
 Storage Buffer    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-161983
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-PAFAH2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-PAFAH2 antibody   

ELISA (EIA), Immunohistochemistry (IHC)

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NCBI/Uniprot data below describe general gene information for PAFAH2. It may not necessarily be applicable to this product.
 NCBI GI #    1765864
 NCBI GeneID    5051
 NCBI Accession #    BAA13468.1 [Other Products]
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 UniProt Secondary Accession #    O15458; Q5SY02; D3DPK1 [Other Products]
 UniProt Related Accession #    Q99487 [Other Products]
 Molecular Weight    44,036 Da [Similar Products]
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 NCBI Official Full Name    platelet-activating factor acetylhydrolase 2
 NCBI Official Synonym Full Names    platelet-activating factor acetylhydrolase 2, 40kDa
 NCBI Official Symbol    PAFAH2 [Similar Products]
 NCBI Official Synonym Symbols   
HSD-PLA2
[Similar Products]
 NCBI Protein Information    platelet-activating factor acetylhydrolase 2, cytoplasmic; SD-PLA2; serine-dependent phospholipase A2
 UniProt Protein Name    Platelet-activating factor acetylhydrolase 2, cytoplasmic
 UniProt Synonym Protein Names   
Serine-dependent phospholipase A2; SD-PLA2; hSD-PLA2
 Protein Family    Platelet-activating factor acetylhydrolase
 UniProt Gene Name    PAFAH2 [Similar Products]
 UniProt Synonym Gene Names    SD-PLA2; hSD-PLA2 [Similar Products]
 UniProt Entry Name    PAFA2_HUMAN
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 NCBI Summary for PAFAH2    This gene encodes platelet-activating factor acetylhydrolase isoform 2, a single-subunit intracellular enzyme that catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). However, this lipase exhibits a broader substrate specificity than simply platelet activating factor. Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist, and both are multi-subunit enzymes. Additionally, there is a single-subunit serum isoform of this enzyme. [provided by RefSeq, Jul 2008]
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 UniProt Comments for PAFAH2    PAFAH2: Has a marked selectivity for phospholipids with short acyl chains at the sn-2 position. May share a common physiologic function with the plasma-type enzyme. Belongs to the serine esterase family.

Protein type: Lipid-binding; Hydrolase; Lipid Metabolism - ether lipid; EC 3.1.1.47

Chromosomal Location of Human Ortholog: 1p36

Cellular Component: cytoplasm

Molecular Function: phospholipid binding; 1-alkyl-2-acetylglycerophosphocholine esterase activity

Biological Process: lipid metabolic process; lipid catabolic process; negative regulation of apoptosis
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 Research Articles on PAFAH2    1. Observational study of gene-disease association. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-PAFAH2 antibodyDiseases associated with anti-PAFAH2 antibody
 Products by Pathway  Pathway Diagram
 Ether Lipid Metabolism Pathway antibodies  Ether Lipid Metabolism Pathway Diagram
 Ether Lipid Metabolism Pathway antibodies  Ether Lipid Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1 publications with PAFAH2 and Inflammation
 Fatty Liver Antibodies  >1 publications with PAFAH2 and Fatty Liver
 Necrosis Antibodies  >1 publications with PAFAH2 and Necrosis
 Drug-Induced Liver Injury Antibodies  >1 publications with PAFAH2 and Drug-Induced Liver Injury
Organs/Tissues associated with anti-PAFAH2 antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >5 publications with PAFAH2 and Brain
 Blood Antibodies  >3 publications with PAFAH2 and Blood
 Heart Antibodies  >1 publications with PAFAH2 and Heart
 Uncharacterized Tissue Antibodies  >1 publications with PAFAH2 and Uncharacterized Tissue
 Muscle Antibodies  >1 publications with PAFAH2 and Muscle
 Embryonic Tissue Antibodies  >1 publications with PAFAH2 and Embryonic Tissue
 Kidney Antibodies  >1 publications with PAFAH2 and Kidney
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