Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow POLR2D rightarrow Polyclonal POLR2D  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Taurine (Pse7367_2220) ELISA Kit
 • Caspase 3 (CASP3) Recombinant Protein
 • Glycogen debranching enzyme (AGL) Recombinant Protein
 • Pregnancy Zone Protein (PZP) ELISA Kit
 • TLR6 Antibody
 • HSV1 Antibody
 • Dual specificity protein phosphatase 7 (DUSP7) Antibody
 • Insulin, peptide Protein
 • Interleukin 1A (IL-1A) ELISA Kit
 • WAP four-disulfide core domain protein 12 (WFDC12) Recombinant Protein
 • pancreatic lipase-related protein 2 (PNLIPRP2) ELISA Kit
 • Oligodendrocytes and Myelin (CNS) Antibody
 • Calsequestrin-2 (CASQ2) ELISA Kit
 • TPS ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-POLR2D antibody :: Rabbit polymerase (RNA) II (DNA directed) polypeptide D Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS714990 anti-POLR2D antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

polymerase (RNA) II (DNA directed) polypeptide D (POLR2D), Polyclonal Antibody

 Also Known As   

Rabbit anti-human polymerase (RNA) II (DNA directed) polypeptide D polyclonal Antibody

 Product Synonym Names    polymerase (RNA) II (DNA directed) polypeptide D; POLR2D; HSRBP4; HSRPB4; RBP4
 Product Gene Name   

anti-POLR2D antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    606017
Section Bar
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
Section Bar
 Purity/Purification    Antigen Affinity Purified
Section Bar
 Immunogen    Human POLR2D
 Storage Buffer    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Section Bar
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-POLR2D antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 Applications Tested/Suitable for anti-POLR2D antibody   

ELISA (EIA), Western Blot (WB)

Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for POLR2D. It may not necessarily be applicable to this product.
 NCBI GI #    16877972
 NCBI GeneID    5433
 NCBI Accession #    AAH17205.1 [Other Products]
Section Bar
 UniProt Secondary Accession #    Q52LT4 [Other Products]
 UniProt Related Accession #    O15514 [Other Products]
 Molecular Weight    16,311 Da [Similar Products]
Table BarTOPTable Bar
 NCBI Official Full Name    Polymerase (RNA) II (DNA directed) polypeptide D
 NCBI Official Synonym Full Names    polymerase (RNA) II (DNA directed) polypeptide D
 NCBI Official Symbol    POLR2D [Similar Products]
 NCBI Official Synonym Symbols   
RBP4; RPB16; HSRBP4; HSRPB4
[Similar Products]
 NCBI Protein Information    DNA-directed RNA polymerase II subunit RPB4; RNA polymerase II subunit B4; RNA polymerase II 16 kDa subunit; RNA polymerase II subunit hsRBP4; DNA-directed RNA polymerase II subunit D; DNA-directed RNA polymerase II 16 kDa polypeptide
 UniProt Protein Name    DNA-directed RNA polymerase II subunit RPB4
 UniProt Synonym Protein Names   
DNA-directed RNA polymerase II subunit D; RNA polymerase II 16 kDa subunit; RPB16
 UniProt Gene Name    POLR2D [Similar Products]
 UniProt Synonym Gene Names    RNA polymerase II subunit B4; RPB16 [Similar Products]
 UniProt Entry Name    RPB4_HUMAN
Section Bar
 NCBI Summary for POLR2D    This gene encodes the fourth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. In yeast, this polymerase subunit is associated with the polymerase under suboptimal growth conditions and may have a stress protective role. A sequence for a ribosomal pseudogene is contained within the 3' untranslated region of the transcript from this gene. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for POLR2D    POLR2D: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB4 is part of a subcomplex with RPB7 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA. Belongs to the eukaryotic RPB4 RNA polymerase subunit family.

Protein type: Transferase; Nucleotide Metabolism - pyrimidine; Transcription initiation complex; RNA processing; Nucleotide Metabolism - purine; EC 2.7.7.6

Chromosomal Location of Human Ortholog: 2q21

Cellular Component: nucleoplasm; DNA-directed RNA polymerase II, core complex; nucleus

Molecular Function: single-stranded RNA binding; translation initiation factor binding; DNA-directed RNA polymerase activity; nucleotide binding; single-stranded DNA binding

Biological Process: transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; viral reproduction; positive regulation of viral transcription; somatic stem cell maintenance; RNA splicing; DNA repair; nuclear mRNA splicing, via spliceosome; positive regulation of translational initiation; mRNA export from nucleus during heat stress; mRNA capping; nucleotide-excision repair; transcription-coupled nucleotide-excision repair; RNA elongation from RNA polymerase II promoter; gene expression; mRNA catabolic process, deadenylation-dependent decay
Table BarTOPTable Bar
 Research Articles on POLR2D    1. Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-POLR2D antibodyPathways associated with anti-POLR2D antibody
 Reference Product  PubMed Publications
 POLR2G antibody  >2 publications with POLR2D and POLR2G
 Products by Pathway  Pathway Diagram
 Abortive Elongation Of HIV-1 Transcript In The Absence Of Tat Pathway antibodies  Abortive Elongation Of HIV-1 Transcript In The Absence Of Tat Pathway Diagram
 DNA Repair Pathway antibodies  DNA Repair Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Dual Incision Reaction In TC-NER Pathway antibodies  Dual Incision Reaction In TC-NER Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Formation Of HIV Elongation Complex In The Absence Of HIV Tat Pathway antibodies  Formation Of HIV Elongation Complex In The Absence Of HIV Tat Pathway Diagram
 Formation Of HIV-1 Elongation Complex Containing HIV-1 Tat Pathway antibodies  Formation Of HIV-1 Elongation Complex Containing HIV-1 Tat Pathway Diagram
 Formation Of RNA Pol II Elongation Complex Pathway antibodies  Formation Of RNA Pol II Elongation Complex Pathway Diagram
 Formation Of The Early Elongation Complex Pathway antibodies  Formation Of The Early Elongation Complex Pathway Diagram
Diseases associated with anti-POLR2D antibodyOrgans/Tissues associated with anti-POLR2D antibody
 Disease Name  Pubmed Publications
 Weight Loss Antibodies  >1 publications with POLR2D and Weight Loss
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >1 publications with POLR2D and Liver
 Blood Antibodies  >1 publications with POLR2D and Blood
 Muscle Antibodies  >1 publications with POLR2D and Muscle
 Intestine Antibodies  >1 publications with POLR2D and Intestine
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions